Multimodal Preclinical Imaging Solutions

Bioscan Multimodality CombinationsSuperior alternatives to the standard trimodality solutionResearchers interested in pursuing both PET and SPECT imaging often consider purchasing a trimodalitysystem that combines PET, SPECT and X-Ray CT in a single cabinet. Bioscan has developed solutions for thesecustomers that rely on two or more discrete systems, because this approach offers significant advantages forsystem performance, research efficiency and workflow.Efficiency Without Performance Compromises• Better efficiency - Dual systems (e.g., PET/CT and SPECT/CT) enable acquisitions to be completed simultaneously,increasing throughput and improving study workflow• No performance compromises - Achieve industry-leadingperformance with each of the modalities you purchase• Small footprint - Two Bioscan systems can fit in less than 9m2,less than many trimodality systems• Upgradable - Bioscan’s modular architecture can enableyou to upgrade your systems to add new modalities or addthroughputF-18 and Tc-99mF-18 (FDG):Heart andBladder (Pink)Tc-99m: Thyroidand Stomach(Green)Research ApplicationsSmall animal imaging - Keys to successMolecular imaging has become a widely-established procedure for diagnosing various disease states andmonitoring the effects of therapeutic treatments in humans. In recent years, molecular imaging has alsobecome a valuable preclinical research tool for studying the development and progression of disease inmouse and rat models, as well as the efficacy of potential therapeutic treatments. Dedicated small animalimaging systems, which include MRI, PET, SPECT, Fluorescence/Bioluminescence, X-Ray CT, and Ultrasound,allow for the characterization of biological, molecular and cellular processes in vivo, with exceptional levels ofresolution and sensitivity.OncologyCNSCardiologyDisease BiologyADME/Tox• Tumor biology• Metastasis• Therapeutic effect• Receptor density• Occupancy studies• Functional studies• Stem cell repair• Metabolic function• Gene expression• Cell trafficking• Biodistribution• Time activity curves(TAC)Performance• Sensitivity• Resolution• UniformityFunctionality• Flexibility• Anatomical localization• Absolute quantificationProductivity• Ease of use• Quality Assurance• ThroughputCost• Standard Configurations• Optional features• Serviceability3