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Life Sciences in the Netherlands - LIAA

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Centre for Society and Genomics (Nijmegen)www.society-genomics.nlNe<strong>the</strong>rlands Toxicogenomics Centre(Maastricht)www.toxicogenomics-centre.nlNe<strong>the</strong>rlands Bio<strong>in</strong>formatics Centre (Nijmegen)www.nbic.nlThe Ne<strong>the</strong>rlands Proteomics Centre (NPC)(Utrecht)www.ne<strong>the</strong>rlandsproteomicscentre.nlBioPartner CentersBPC Amsterdamwww.asp.nlBPC Gron<strong>in</strong>genSee: www.technopartner.nlBPC leidenwww.biopartnerleiden.nlBPC Maastrichtwww.bpcm.nlBPC UtrechtE-mail: g.vanstrien@hold<strong>in</strong>gs.uu.nlBPC Wagen<strong>in</strong>genwww.biopartnerwagen<strong>in</strong>gen.nl<strong>the</strong>rapy improvement <strong>in</strong> <strong>the</strong> com<strong>in</strong>g decade. For<strong>in</strong>stance, <strong>the</strong> genomics signature of <strong>the</strong> cancer and thatof <strong>the</strong> patient may serve <strong>in</strong> <strong>the</strong> near future as a basis onwhich to choose <strong>the</strong> most effective <strong>the</strong>rapy for <strong>the</strong><strong>in</strong>dividual patient (‘personalized medic<strong>in</strong>e’) toimprove cancer patients chances of recovery and <strong>the</strong>irquality of life.CSG’s mission is to be a lead<strong>in</strong>g centre forunderstand<strong>in</strong>g and stimulat<strong>in</strong>g <strong>the</strong> <strong>in</strong>teraction betweensociety and genomics, both nationally and<strong>in</strong>ternationally.It is <strong>the</strong> mission of <strong>the</strong> Ne<strong>the</strong>rlands ToxicogenomicsCentre that <strong>the</strong> toxicogenomics approach should beused to take <strong>the</strong> unique opportunity of develop<strong>in</strong>ghighly predictive screens based on gene expression orprote<strong>in</strong>/metabolite f<strong>in</strong>gerpr<strong>in</strong>ts, to be used for <strong>in</strong> dep<strong>the</strong>valuation of chemical safety for human health,<strong>the</strong>reby replac<strong>in</strong>g/reduc<strong>in</strong>g/ref<strong>in</strong><strong>in</strong>g animalexperiments, and improv<strong>in</strong>g <strong>the</strong> scientific basis ofchemical risk assessment.Foundation NBIC <strong>in</strong>itiates and coord<strong>in</strong>ates research,education and support activities to stimulate <strong>the</strong>development of <strong>the</strong> field of bio<strong>in</strong>formatics.Bio<strong>in</strong>formatics is a new discipl<strong>in</strong>e that comb<strong>in</strong>es<strong>in</strong>formatics and ma<strong>the</strong>matics with <strong>the</strong> life sciences. Itis closely related to genomics, which analyses genome<strong>in</strong>formation. The genome governs <strong>the</strong> function<strong>in</strong>g andbiological processes of <strong>the</strong> organism. These studiesgenerate enormous amounts of data and <strong>in</strong>formation,and huge computer capacities are needed for fur<strong>the</strong>rprocess<strong>in</strong>g and analysis. Bio<strong>in</strong>formatics provides <strong>the</strong>knowledge, applications and analytical tools to handlegenomics data, and is crucial to achieve results <strong>in</strong> <strong>the</strong>life sciences.The Ne<strong>the</strong>rlands Proteomics Centre (NPC) is astrategic collaboration of research groups from sixuniversities, three academic medical centres andseveral biotech companies.Initiated by <strong>the</strong> Municipality of Amsterdam, <strong>the</strong> Dutchorganization for Scientific Research (NWO), <strong>the</strong>Rabobank and <strong>the</strong> University of Amsterdam (UvA),ASP was founded <strong>in</strong> 1989 to promote transfer ofknowledge from educational <strong>in</strong>stitutions to small andmedium-sized bus<strong>in</strong>esses.In April 2001 BioPartner Center Leiden was <strong>the</strong> firstBioPartner Center <strong>in</strong> The Ne<strong>the</strong>rlands to locate biotechstart-ups. It resides <strong>in</strong> <strong>the</strong> BioScience Park <strong>in</strong> Leiden.BioPartner Center Maastricht offers bus<strong>in</strong>essaccommodation to life sciences start-ups. Its ma<strong>in</strong>mission is to <strong>in</strong>crease <strong>the</strong> chance of success for <strong>Life</strong><strong>Sciences</strong> start-ups. Through its three tissue <strong>in</strong>cubatorsand GMP cell <strong>the</strong>rapy clean rooms, <strong>the</strong> Center offers acomplete range of facilities from laboratory scale toGMP production for <strong>Life</strong> <strong>Sciences</strong> companies active <strong>in</strong><strong>the</strong> fields of cell <strong>the</strong>rapy and cell cultur<strong>in</strong>g.The bus<strong>in</strong>ess <strong>in</strong>cubator BioPartner Center Wagen<strong>in</strong>genoffers a unique environment for life sciences start-ups,a place where facilities and knowledge can be shared.<strong>Life</strong> <strong>Sciences</strong> <strong>in</strong> <strong>the</strong> Ne<strong>the</strong>rlands 17

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