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Lecture Evolution of Immunity.pdf - School of Life Sciences

Lecture Evolution of Immunity.pdf - School of Life Sciences

Lecture Evolution of Immunity.pdf - School of Life Sciences

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INVERTEBRATE IMMUNITY: LATER DEVELOPMENTS1980s-onwardsBayne Smith RaftosLectins provide biochemicaldiversity for recognition <strong>of</strong> nonselfcarbohydrate moieties(Bayne)Protease cascades representprimitive forms <strong>of</strong> complement(Smith)Biochemical relationship <strong>of</strong> certain immune proteins to Ig Superfamilye.g. FREPS, hemolin (Adema, Faye)Inducible proteins (e.g. cecropins) confer adaptability oninvertebrates (Boman, Hultmark, H<strong>of</strong>fmann)Gene homologues to complement in invertebrates (Smith, Raftos)

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