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Community-Based Surveillance of Antimicrobial Use and ...

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<strong>Community</strong>-based surveillance <strong>of</strong> antimicrobial use<strong>and</strong> resistance in resource-constrained settingsprophylaxis policy for Pneumocystis jiroveci in HIV‐positive patients in the public sector. Asindividual patients would receive doses sufficient for use for a month, this would bereflected in the total DDDs prescribed.Table 6.6 (A-D): Monthly use <strong>of</strong> specific ABM from February 2003 to January 2004Percentage <strong>of</strong> prescriptions containing specific ABMNumber <strong>of</strong> DDDs <strong>of</strong> specific ABM per 100 patientsA1. CotrimoxazoleA2. Cotrimoxazole% prescriptions with ABM20151050Private pharmacyPublic PHCDispensing practitioner*AverageFeb Mar Apr May Jun Jul Aug Sep Oct Nov Dec JanNo.DDDs ABM / 100 patients100806040200Private PharmacyPublic PHCDispensing practitioner*AverageFeb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan% prescriptions with ABM20151050B1. PenicillinsPrivate PharmacyPublic PHCDispensing practitioner*AverageFeb Mar Apr May Jun Jul Aug Sep Oct Nov Dec JanNo.DDDs ABM / 100 patients100806040200B2. PenicillinsPrivate PharmacyPublic PHCDispensing practitioner*AverageFeb Mar Apr May Jun Jul Aug Sep Oct Nov Dec JanC1. QuinolonesC2. Quinolones% prescriptions with ABM20151050Private PharmacyPublic PHCDispensing practitioner*AverageFeb Mar Apr May Jun Jul Aug Sep Oct Nov Dec JanNo.DDDs ABM / 100 patients100806040200Private PharmacyPublic PHCDispensing practitioner*AverageFeb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan% prescriptions with ABM20151050D1. TetracyclinesPrivate PharmacyPublic PHCDispensing practitioner*AverageFeb Mar Apr May Jun Jul Aug Sep Oct Nov Dec JanNo.DDDs ABM / 100 patients100806040200D2. TetracyclinesPrivate PharmacyPublic PHCDispensing practitioner*AverageFeb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan* Private facility6.3.3 Effect <strong>of</strong> ABM on AMRIt was not expected that ABM use would be associated with any AMR changes over theperiod <strong>of</strong> the pilot study. Although based on scanty data, it was notable that AMR tocotrimoxazole appears to be high among both H. influenzae <strong>and</strong> S. pneumoniae isolates.76

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