MADIT Randomized Trial to Reduce Inappropriate Therapy ... - 1

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FREQUENCY AND HAZARD RATIOS FOR INAPPROPRIATE THERAPY,DEATH, AND SYNCOPE BY TREATMENT GROUPTreatmentGroupsTreatment Group ComparisonsEvents # of patients B vs. A C vs. AA B Cn=514 n=500 n=486HazardRatioP-valueHazardRatioP-valueFirstInappropriateRx105 21 26 0.21
Arrhythmias Triggering FirstInappropriate TherapiesArrhythmiasTreatment t GroupA B C(# Pts. 1 st Inapp. Therapies)At Fib/Flut 24 11 5Regular SVT 78 9 17Other 3 1 4Note: marked reduction in patients with1 st inappropriate therapiesin High-rate (B) and Duration-delay (C) groups for At Fib/Flut andRegular SVT when compared to Conventional therapy (A).
Page 1 and 2: MADIT Randomized Trial to ReduceIna
Page 3 and 4: MADIT-RIT: BACKGROUND• ICD is hig
Page 5 and 6: MADIT-RIT: Three Treatment Arms*Ran
Page 7 and 8: MADIT-RIT: MADIT-RIT Prespecified P
Page 9 and 10: Baseline Demographic and ClinicalCh
Page 11: Figure 2.Cumulative Probability of
Page 15 and 16: MADIT-RIT: CONCLUSIONSImproved ICD

MADIT Randomized Trial to Reduce Inappropriate Therapy ... - 1

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