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MADIT-RIT: BACKGROUND• ICD is highly effective in reducing mortality inhigh-risk cardiac pts.• Despite sophisticated device-detectionalgorithms, 8-40% of ICD therapies areinappropriate with adverse side effects• Question: can ICD devices be reprogrammedto safely reduce inappropriate therapies?

Serelaxin, A Novel Treatment for Acute Heart Failure- The RELAX - 1

Medical Faculty of Ruperto Carola University Heidelberg

Hartfalen: epidemiologie, risicofactoren en toekomst

DISCLOSURE INFORMATIONArthur J. Moss, MDCompanyBoston ScientificRelationshipResearch GrantHold no stock or stock options in anydevice company. Not a member of anycorporate advisory group or speakers’bureau.

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Page 5 and 6: MADIT-RIT: Three Treatment Arms*Ran
Page 7 and 8: MADIT-RIT: MADIT-RIT Prespecified P
Page 9 and 10: Baseline Demographic and ClinicalCh
Page 11 and 12: Figure 2.Cumulative Probability of
Page 13 and 14: Arrhythmias Triggering FirstInappro
Page 15 and 16: MADIT-RIT: CONCLUSIONSImproved ICD

MADIT Randomized Trial to Reduce Inappropriate Therapy ... - 1

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