Professor Narinder Rawal, MD, PhD, FRCA (Hon) - AKUTNE.CZ

Romundstad L, Stubbhaug AIn summary, there is evidence that glucocorticoids alleviate acute andcontinued postoperative pain by suppressing inflammatory mediators, glialactivation, reducing neural activity, sympathetic sprouting, and centralneuroplastic changes such as central sensitization.…there is evidence supporting the perioperative use of glucocorticoids for therelief of acute and sustained postoperative pain. What we now need is properlysized studies investigating long-term effects of perioperative glucocorticoids onhuman postoperative pain