Surfactant replacement therapy in acute respiratory ... - RM Solutions

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Clinical trial in pediatrics• RCT6 ( 3 ALI/ARDS an 3 bronchiolitis)• Case report 20• Uncontrolled 7• Retrospective 3• Case control 1• Non randomized 1Duffett M, Choong K, Ng V, RandolphA,Cook DJ: Surfactant therapy for acuterespiratory failure in children: asystematic review and meta-analysis.Crit Care 2007.
Clinical trial in pediatrics ALI/ARDS• Improve gas exchange, reduce PIP and shorten CPPV and ICU stayLuchetti et al, Porcine-derived surfactanttreatment of severe bronchiolitis Scaactaaneasthesiol 1998 Aug;42(7):805-10.• Reduce PIP, , MV days p
Page 1 and 2: Surfactant Replacement Therapyin Ch
Page 3 and 4: Case 1• 2 yrs boy 50% flam burn ,
Page 5 and 6: Case 2• Preterm 24/52, CA 10 days
Page 8 and 9: Surfactant• Type II pneumocytes.
Page 10: Type of SurfactantPhLip SPA SPB SPC
Page 13: Clinical trial adult• 4 RCT• Fa
Page 17 and 18: Clinical trial in pediatrics• Pha
Page 19 and 20: Clinical trial in pediatrics• Tre
Page 21 and 22: Clinical trial in pediatrics• Sub
Page 23 and 24: Ventilator-free daysDuffett M, choo
Page 25 and 26: Duration PCCU stayDuffett M, choong
Page 27 and 28: Clinical trial in pediatricsInitial
Page 29 and 30: Summery• Surfactant not recommend

Surfactant replacement therapy in acute respiratory ... - RM Solutions

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