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Rexam<br />

Phone: +33 1 58 47 56 82<br />

Fax: +33 1 58 47 56 24<br />

Email: laurence.quesdeville@rexam.com<br />

www.rexam.com/pharma<br />

<strong>PRESS</strong> <strong>KIT</strong><br />

<strong>PRESS</strong> <strong>KIT</strong><br />

March, 2008<br />

MDM East<br />

June 3-5, 2008<br />

Booth 1725 Rexam Pharma<br />

Press kit and high resolution images<br />

available at:<br />

http://www.rexam.com/tradeevents


I. Key product launches<br />

i. MLx rigid plastic multilayer technology<br />

combining drug protection with user<br />

safety<br />

ii. Rexam launches the Safe’n’Sound, a<br />

passive safety device for 1 ml long<br />

syringes<br />

iii. Secupharm / Evipharm: New integrated<br />

filled-in-line desiccant cap for bottles<br />

iv. Sof’bag: the airless package to dispense<br />

creams, lotions and gels<br />

v. Innovation in nasal sprays<br />

vi. Embedded RFID bottles support a “safe<br />

and secure” supply chain for the<br />

Pharmaceutical Industry<br />

II. Rexam strengthens position in healthcare<br />

packaging and medical devices<br />

III. Company profile<br />

Rexam<br />

Phone: +33 1 58 47 56 76<br />

Fax: +33 1 58 47 56 24<br />

Email: mailboxpharma@rexam.com<br />

www.rexam.com/pharma<br />

<strong>PRESS</strong> <strong>KIT</strong><br />

March, 2008


MLX Plastic Vials<br />

Rexam<br />

Phone: +33 1 58 47 56 90<br />

Fax: +33 1 58 47 58 24<br />

Email: isabelle.delcroix@rexam.com<br />

www.rexam.com/pharma<br />

PRODUCT NEWS<br />

March, 2008<br />

MLx rigid plastic multilayer technology<br />

combining drug protection with user<br />

safety<br />

MLx is a multi-layer, injection blow-molded technology<br />

designed to optimize barrier performance as well as<br />

strength, clarity and pharmaceuticals compatibility.<br />

Rexam’s MLx technology combines barrier properties<br />

to moisture, oxygen and vacuum resistance.<br />

Compared to glass, it brings compatibility with fragile<br />

formulations such as proteins and resistance to<br />

breakage to ensure user safety.<br />

The technology is especially suitable for biotech drugs<br />

that require the best protection and for products that<br />

could endanger users in case of accidental exposure.<br />

Since MLx packaging is shatter resistant, it allows<br />

automated handling of vials to improve productivity<br />

and better protection throughout the supply chain.<br />

Our proprietary multilayer technology can be adapted<br />

to our clients’needs with the full support of our<br />

Development Team and multilayer experts.


Passive Safety Device for Prefilled Syringes :<br />

Safe’n’Sound 1 ml long version<br />

Rexam<br />

Phone: +33 1 58 47 56 90<br />

Fax: +33 1 58 47 56 24<br />

Email: isabelle.delcroix@rexam.com<br />

www.rexam.com/pharma<br />

PRODUCT NEWS<br />

March, 2008<br />

Rexam launches the Safe’n’Sound,<br />

a passive safety device for 1 ml<br />

long syringes<br />

In response to the continued concern over<br />

unprotected needle exposures and the mandated<br />

Safety and Prevention regulations, Rexam has<br />

developed a fully passive safety device for<br />

prefilled syringes: the Safe’n’Sound.<br />

The Safe’n’Sound provides healthcare<br />

industries and patients with a full protection from<br />

needlesticks to avoid any contamination.<br />

Compared to a standard syringe, the<br />

Safe’n’Sound system guarantees passive<br />

protection as the syringe retracts automatically<br />

in the system after the injection without any<br />

action by the user.<br />

Compact, light and transparent, the<br />

Safe’n’Sound has only three components (a<br />

sleeve, a body and a spring).<br />

This new device is introduced after a standard<br />

version for syringes 1 ml short.


Secupharm<br />

Evipharm<br />

Rexam<br />

Phone: +33 1 58 47 56 90<br />

Fax: +33 1 58 47 58 24<br />

Email: isabelle.delcroix@rexam.com<br />

www.rexam.com/pharma<br />

PRODUCT NEWS<br />

March, 2008<br />

Evipharm/ Secupharm: an innovative<br />

integrated filled-in-line desiccant cap for bottles<br />

The Rexam plant in Offranville, specialized in primary<br />

packaging, has developed an innovative process which<br />

includes injection of plastic parts, automated assembly and<br />

desiccant filling.<br />

From the quality standpoint, improved traceability and process<br />

control reinforce existing GMP compliance.<br />

Secupharm and Evipharm were developed with pharmacopoeia<br />

compliant materials. Both fit 32 mm-neck bottles from 20ml up to<br />

100ml, featuring thick HDPE walls to guarantee the best moisture<br />

barrier and ensure high rigidity.<br />

Regarding Supply Chain, a shorter production cycle with fewer<br />

parts to assemble leads to performance & improved reliability.<br />

These benefits come at a competitive cost thanks to a streamlined<br />

manufacturing process.<br />

Evipharm has a filled-in desiccant ranging from 0.6g to 3.4g and<br />

tamper evident features.<br />

Secupharm is the new reference in child-resistant “push-and-turn”<br />

closures, with the same tamper evident features as Evipharm.<br />

Rexam can provide pharmaceutical customers with a flexible<br />

filled-in-line desiccant cap manufactured in an integrated process<br />

for best traceability and best quality.


Sof’bag<br />

Rexam<br />

Phone: +33 1 58 47 56 81<br />

Fax: +33 1 58 47 58 24<br />

Email: julie.brun@rexam.com<br />

www.rexam.com/pharma<br />

PRODUCT NEWS<br />

March, 2008<br />

SOF’BAG: the airless package to dispense<br />

creams, lotions and gels<br />

Rexam Pharma presents a total packaging system for<br />

transdermal and topical application. The Sof’bag is<br />

easy-to-use for patients while keeping filling simple<br />

and logistics easy for drug manufacturers.<br />

Developed by Rexam Pharma to ensure that<br />

pharmaceutical formulations are delivered with<br />

extreme accuracy, the Sof’bag is delivered in two<br />

components: “a bag and bottle assembly” and “a<br />

pump and cap assembly”.<br />

The multilayer bag in the plastic bottle guarantees a<br />

maximum protection against contamination and<br />

oxidation.<br />

The metering pump dosing from 0.50 ml up to 1.50<br />

ml was developed especially for pharmaceutical use.<br />

All materials and performances are compliant with US<br />

and European regulatory requirements.<br />

The packaging, available in 100 ml, can also be used<br />

in all positions making it a smart choice for easing<br />

consumers’ lives.<br />

Rexam Pharma manufactures both components<br />

ensuring a perfect match for a better performance.<br />

The Sof’Bag is currently on the market both in the US<br />

and in Europe for hormonal treatments.


Snap-on: M17<br />

complete packaging<br />

Rexam<br />

Phone: +33 1 58 47 56 81<br />

Fax: +33 1 58 47 86 24<br />

Email: julie.brun@rexam.com<br />

www.rexam.com/pharma<br />

Innovation in nasal sprays<br />

<strong>PRESS</strong> <strong>KIT</strong><br />

March, 2008<br />

Rexam Pharma spray expertise is renowned. Tuned<br />

for consistency, our pumps are tested and<br />

guaranteed by our laboratory.<br />

Through digital simulation, we give our customers the<br />

best solutions to deliver their formulations. Our teams<br />

include an integrated innovation department, a fullyequipped<br />

laboratory, material and spray experts.<br />

We carry a vast range of pumps, valves, applicators,<br />

rigid bottles and squeezable sprays in all shapes and<br />

sizes to provide you a “One-Stop-Shop” solution.<br />

These pump, applicator and bottle packages are<br />

easy to use on filling lines. They guarantee increased<br />

productivity while ensuring safety thanks to the tight<br />

fit between the pump and the bottle.<br />

In addition, with the Rexam engineered snapon<br />

M17 neck, rubber sealing gaskets, a known<br />

source of compatibility problems are eliminated.<br />

Rexam can also supply snap-on pumps for standard<br />

20 mm necks which ensure an extensive choice of<br />

containers in plastics and in glass.


Rexam’s embedded RFID bottles support a “safe and secure”<br />

supply chain for the Pharmaceutical Industry<br />

Rexam announces new RFID enabled containers for the pharmaceutical industry that<br />

will bring a robust and reliable solution.<br />

Rexam has developed fully integrated Radio Frequency Identification enabled plastic<br />

pharmaceutical bottles that allow compliance with FDA recommendations. The tags (either<br />

HF or UHF) are encapsulated into discs and molded into containers combining fully<br />

traceable life cycle and counterfeiting prevention.<br />

Using a patented technology, these new bottles allow for greater robustness and reliability<br />

of RFID functions. The integration of the tag with the bottles enables traceability from the<br />

origin of the process and ensures 100% viable tags. Rexam’s RFID solution offers less<br />

damage of tags as molded-in integration protects tag and fewer null reads from tag-to-tag<br />

contact on conveyer lines.<br />

As a renowned supplier in packaging for prescription drugs, Rexam has a comprehensive<br />

range of bottles and closures with tamper evident and child resistant features that can be<br />

delivered with this new, fully industrial, embedded RFID tags.<br />

Rexam<br />

Phone: +33 1 58 47 56 90<br />

Fax: +33 1 58 47 58 24<br />

Email: isabelle.delcroix@rexam.com<br />

www.rexam.com/pharma<br />

<strong>PRESS</strong> <strong>KIT</strong><br />

March, 2008


<strong>PRESS</strong> RELEASE<br />

March, 2008<br />

Rexam strengthens position in healthcare packaging and<br />

medical devices<br />

Rexam completed the acquisition of O-I Plastics, a leading US manufacturer of rigid<br />

plastic healthcare packaging and plastic closure systems in August this year. The<br />

acquisition is consistent with Rexam’s strategy to strengthen its positions in growth areas<br />

and has transformed Rexam’s Plastic Packaging business, creating leading positions in<br />

two important plastic packaging segments: Healthcare Packaging and Closures.<br />

Rexam already had extensive operations in healthcare packaging through its Pharma<br />

business in Europe, the US and India. The acquisition is an excellent fit in terms of,<br />

technologies, innovation, end use applications and geography and will enable us to<br />

deliver even further value to our customers.<br />

Rexam<br />

Phone: +33 1 58 47 56 82<br />

Fax: +33 1 58 47 56 24<br />

Email: laurence.quesdeville@rexam.com<br />

www.rexam.com/pharma


Rexam<br />

Phone: +33 1 58 47 56 82<br />

Fax: +33 1 58 47 56 24<br />

Email: laurence.quesdeville@rexam.com<br />

www.rexam.com/pharma<br />

Company profile<br />

<strong>PRESS</strong> <strong>KIT</strong><br />

March, 2008<br />

Rexam is a leading global consumer packaging company<br />

and the largest beverage can maker in the world.<br />

With 23,500 people in more than 20 countries, Rexam’s<br />

sales from ongoing operations are approximately £3.7<br />

billion.<br />

Through the acquisition of O-I Plastics, Rexam has<br />

reinforced its leadership in healthcare packaging,<br />

drug delivery systems and medical devices.<br />

Rexam’s pharma organization has a strong focus on the<br />

pharmaceutical industry’ needs with comprehensive<br />

resources in innovation, development & industrialization<br />

and full GMP manufacturing.<br />

With global operations spanning across Europe, the USA<br />

and Asia, Rexam’s pharma organization has a recognized<br />

expertise in :<br />

-drug delivery and medical devices<br />

-metering pumps and valves<br />

-plastic primary packaging<br />

-diagnostic disposables<br />

For further information, visit Rexam’s website at<br />

www.rexam.com/pharma

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