16 של האיגוד הישראלי לפסיכיאטריה ביולוגית - ×”×›× ×¡ ×”×©× ×ª×™ ה 2012 20-22 ...

הכנס השנתי ה-‏‎16‎ של האיגוד הישראלי לפסיכיאטריה ביולוגיתהגושרים,‏20-22 במרץ 201220 במרץקבלת פנים,‏ הרשמה וחלוקת חדריםיום שלישי,‏12:30-14: 00אולם יסמין Symposium 3Marijuana: a therapeutic target to theeffects of traumaChair: Irit AkiravEndocannabinoids – "on demand"neuroprotective system in traumatic braininjuryShohami E. Hebrew University of JerusalemCannabinoids: a potential therapeutic targetfor the effects of stress and emotional traumaAkirav I. Haifa UniversityFrom cognitive deficits to neuroprotection:Behavioral and biochemical effects of ultralowdoses of tetrahydrocannabinol (THC)Sarne Y. Tel Aviv University14:00-15:30אולם אורן Symposium 2 2The 18 kDa Translocator Protein(TSPO) in neurological disordersChair: Moshe GavishPsychiatric Perspectives of the TSPOWeizman A. Tel Aviv UniversityTSPO and neurodegenerationVeenman L. Technion HaifaConsideration of TSPO as an influencer ofbrain tumor progressionBode J. University of Goettingen Germanyאולם אורן Symposium 1 1Advances in PsychiatricPharmacogenomicChairs: Beni Lerer and Alan ApterAntipsychotic drugs: Pharmacogenomicprediction of adverse effectsLerer B. Hadassah Medical Center and HebrewUniversity of JerusalemNovel insights on nicotine dependencegenetics: Focus on the role of the CHRNA5–A3–B4 gene clusterGreenbaum L. Hadassah Medical Center andHebrew University of JerusalemThe Pharmacogenetics of suicidal adversereactions to SSRI medications in Childrenand AdolescentsApter A. Schneider Children's Medical Center15:30-16:00 הפסקת קפה ותצוגת חברות בלובי1

אולם יסמין Symposium 6Unraveling the Stress Response:Understanding the Mechanisms of CopingChairs: Hagit Cohen and Alon ChenCRF receptors type 1 and 2 may mediate the"Incubation of fear" leading to post traumaticstress disorderElharrar E. Bar-Ilan UniversityDNA methyltransferase 3a in the prefrontal cortexregulates anxiety and fear extinctionElliott E. Weizmann Institute of Science and Bar-IlanUniversityMouse model of empathy reveals differences inneural activity underlying recollection ofpsychological vs. physical traumaFurman O. Weizmann Institute of Science, RehovotSusceptibility to PTSD-like behavior is mediatedby CRF receptor type 2 levels in the bed nucleus ofthe stria terminalisLebow M. Weizmann Institute of Science, RehovotBeyond the HPA-axis: the role of the gonadalsteroid hormone receptors in modulating stressrelatedresponses in an animal model of PTSDCohen H. Beer-Sheva Mental Health Center, Ben-Gurion University of the Negev16:00-17:30אולם אורן Symposium 5 2Changing Addictive BehaviorsChairs: Aron Weller & Abraham ZangenDifferent eating habits may lead toalterations in cocaine seeking behaviorBarnea R. Bar-Ilan UniversityCan lateral habenula stimulation be aneffective treatment for cocaine addiction?Lax E. Bar-Ilan UniversityThe bi-directional effects of depressionand drug-addiction: Enhancement ofaddictive behaviors following chronicstress in ratsZilkha N. Weizmann Institute of Science,RehovotCue-induced reinstatement of cocaineseeking in the rat ‘conflict model’ aftervarious periods of imposed abstinenceBarnea-Ygael N. Ben-Gurion University ofthe Negevאולם אורן Symposium 4 1Molecular and Cellular Approach inSchizophrenia TranslationalResearch: Innovative HorizonsChairs: Ilana Gozes & Beni LererTransplantation of human adult stem cellsprotects against social deficit exhibited bysub-chronically Phencyclidine treated miceBarzilay R. Tel Aviv UniversityInduced Ahi1 over-expression in the mousebrain affects neuronal migration in thedeveloping cortexSlonimsky A. Hadassah, Hebrew UniversityMedical Center, JerusalemNAP (davunetide) enhances cognitivebehavior and inhibits clozapine relatedimpairments in the STOP mouse - amicrotubule-deficient model ofschizophreniaMerenlender- Wagner A. Tel Aviv UniversityThe two member protein family of activitydependentneuroprotective protein (ADNP)and ADNP2 are deregulated in lymphocytesfrom schizophrenia patientsGozes I. Tel Aviv University17:30-18:00 הפסקת קפה ותצוגת חברות בלובי2

אולם אורן 18:00-19:30פרס האיגוד לעבודת מחקר בחסות חברת אלי לילידברי ברכה:‏ יו"ר האיגוד,‏ פרופ'‏ אריה שלופרסי האיגוד לעבודות מחקר :פרס על עבודה מצטיינת במסלול הקליני מוענק על ידי פרופ'‏ אבי ויצמןפרס על עבודה מצטיינת במסלול הבסיסי מוענק על ידי פרופ'‏ חגית כהןועדת השיפוט:‏ פרופ'‏ אבי ויצמן,‏ פרופ'‏ חיים בלמקר,‏ פרופ'‏ חגית כהן,‏ פרופ'‏ גל ריכטר-לויןOpening Keynote Speaker:Prof. Mark OplerDepartment of Psychiatry, New York University School of MedicineA Measure of Truth: Rating Scales in Clinical ResearchIntroduced by: Prof. Gil ZalsmanSponsored by Janssen19:30 ארוחת ערבאולם אורן 20:30-22:30Poster Session-I & Refreshmentsועדת השיפוט:‏פרופ'‏ דורית בן שחר,‏ פרופ'‏ אהרון וולר,‏ ד"ר תמר גרין,‏ ד"ר יובל בלוך,‏ ד"ר אבי אביטל23:00 נפגשים בפאב3

Emotion and Motivation I1. Polymorphisms in the serotonin transporter gene and empathic embarrassment tendencyAdler N. 1 , Perach- Blum N. 1 , Mayesless N. 1 , Shalev I. 2 , Uzefovsky F. 2 ,Ebstein R.P. 2 and Shamay- Tsoory S.G. 11 University of Haifa; 2 Hebrew University2. Effects of transcranial magnetic stimulation (TMS) on motivation processes in human prefrontal cortexAverkin A. 2 , Shahar H. 1 , Isserles M. 3 , Pell G.S. 4 and Zangen A. 11 Ben-Gurion University of the Negev, Faculty of Natural Sciences, Department of Life Sciences; 2 Department of Neurobiology, The Weizmann Institute of Science, Rehovot,Israel ; 3 Department of Psychiatry, Hadassah-Ein Kerem, Jerusalem, Israel ; 4 Brainsway, Jerusalem, Israel3. Sigma-1 agonist as a treatment for cocaine addictionBen-Moshe H. 1 , Maayan R. 2 , Weizman A. 2,3 and Yadid G. 11 Faculty of Life Sciences and the Leslie and Gonda Brain Research Center,Bar-Ilan University; 2 Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Tel AvivUniversity; 3 Geha Mental Health Center, Petah Tikva, Israel4. Modifications in sense of self are associated with rest-related prefrontal cortex functional connectivity: a combined deep-TMS - fMRI studyGruberger M. 1,2,3 , Levkovitz Y. 2,4 , Harel E.V. 2,4 , Harari H. 2,4 , Ben-Simon E. 1,4 , Sharon H. 1,4 , Hendler T. 1,3,4 and Zangen A. 51 Functional Brain Center, Wohl Institute for Advanced Imaging, Tel-Aviv Sourasky Medical Center; 2 The Emotion-Cognition Research Center, Shalvata Mental HealthCenter; 3 Department of Psychology, Tel-Aviv University; 4 Faculty of Medicine, Tel-Aviv University; 5 Department of Life Sciences, Ben-Gurion University5. Short- and long-term effects of sleep deprivation on attention and motor-abilities in ratsZubedat S. 1 , Freed Y. 3 , Eshed Y. 3 , Ritter A. 1 , Nachmani M. 1 , Harush R. 1 and Avital A. 1,21 Faculty of Medicine, Technion - Israel Institute of Technology, Haifa; 2 Emek Medical Center, Afula, Israel; 3 Freed Homeopathy Clinic, Hod HasharonChildren & Development I6. Neuroimmunological function in parents of children suffering from cancerBenaroya-Milshtein N. 1,2 , Apter A. 1 , Yaniv . 3 , Oded Y. 1 , Stern B. 1 ,Bengal Y. 3 , Kodman Y. 3 , Shemer E. 1 , Pick C.G. 2 , Buchwald I. 3 and Valevski A. 41 Department of Psychological Medicine, Schneider Children''s Medical Center of Israel, Petah Tikva; 2 Department of Anatomy, Sackler Faculty of Medicine, Tel AvivUniversity; 3 Department of Hemato-Oncology, Schneider Children''s Medical Center of Israel, Petah Tikva; 4 Geha Mental Health Center, Petah Tikva, Israel, affiliated to SacklerFaculty of Medicine, Tel Aviv7. Post-weaning short-term stress effects in the WKY rat model of depression and anxietyGutman A. 1,2 , Shbiro L. 1,3 , Weller A. 1,3 and Zalsman G. 4,51 Gonda Brain Research Center, Bar-Ilan University, Ramat-Gan, Israel; 2 Department of Psychology, Tel Aviv University, Tel Aviv, Israel; 3 Department of Psychology, Bar-IlanUniversity, Ramat-Gan, Israel; 4 Psychiatry Department, Sackler School of Medicine, Tel Aviv University; 5 Geha Mental Health Center, Petach Tikva, Israel8. A comparison of effects on mothers of constrained and continuous missile bombardment (Galilee, July-August 2006, vs Gaza surround, 2000-2008).Moshe S. 1 , Weintraub Z. 3 , Haskell E. 1 , Maayan-Metzger A. 4 , Mazal T. 1 , Mazor A. 1 , Sharabi A. 2 , Schulkin J. 2 , Wajc M. 1 , Guterman N., Harari O. 1 , ZangenS. 5 and Leshem M. 11 Department of Psychology, University of Haifa; 2 American College of Obstetricians and Gynecologists; 3 Neonatal Department, Western Galilee Medical Center; 4 NeonatalDepartment, Sheba Medical Center; 5 Neonatal Department, Barzilai Medical Center9. Transgenerational Effects: Lebanon War II – The Next GenerationShachar-Dadon A. 1 , Gini M. 2 , Weintraub Z. 3 , Maayan-Metzger A. 4 ,Haskell E. 1 , Paz R. 1 , Rahamim O, Wajc M. 1 , Schmeltzer M. 1 , Maman H. 1 , Mazal T. 1 , SchulkinJ. 5 and Leshem M. 11 Department of Psychology, University of Haifa; 2 Milman Center for Children with Communication and Developmental Disorders, Haifa; 3 Neonatal Department, Western GalileeMedical Center; 4 Neonatal Department, Sheba Medical Center; 5 American College of Obstetricians and Gynecologists4

Stress and trauma I10. Cannabinoids ameliorate impairments induced by chronic stress to synaptic plasticity and short-term memoryAbush H. and Akirav I.University of Haifa, Department of Psychology11. Re-experiencing, avoidance and hyper-arousal: a novel animal model for PTSDAga-Mizrachi S. 1 , Cymerblit-Sabba A. 1 , Zubedat S. 1 and Avital A. 1,21 Bruce and Ruth Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; 2 Emek Medical Center, Afula, Israel12. ''Juvenile stress'' exacerbates the impact of an exposure to an odor reminder of a traumatic experience in adulthoodArdi Z. 1,2.3 , Richter-Levin A. 2,3 and Richter-Levin G. 1,2,3,41 Neurobiology and Etiology Department, University of Haifa, Israel; 2 The Brain and Behavior Research Center, Israel; 3 The Institute for the Study of Affective Neuroscience(ISAN); 4 Psychology Department, University of Haifa, Israel13. Thalidomide analog, 3’6,dithiothalidomide, administration post minimal traumatic brain injury reduce TNF-? and improve cognitiveperformance in mice.Baratz R. 1 , Rubovitch V. 1 , Tweedie D. 2 , Greig N.H. 2 and Pick C.G. 11 Department of Anatomy and Anthropology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, ; 2 Laboratory of Neurosciences, Intramural Research Program, NationalInstitute on Aging, National Inst14. Post-exposure sleep deprivation facilitates correctly-timed interactions between glucocorticoid and adrenergic systems which attenuatetraumatic stress responsesCohen S. 1,2 , Kozlovsky N. 2 , Matar M.A. 2 , Kaplan Z. 2 , Zohar J. 3 and Cohen H. 1,21 Department of Psychology, Ben Gurion University, Beer Sheva, Israel; 2 Ministry of Health, Anxiety and Stress Research Unit, Ben-Gurion University, Beer Sheva, Israel; 3 The ChaimSheba Medical Center, Division of Psychiatry, Tel-Aviv University, Israel15. Alterations in gene expression in Dorsal / Ventral Hippocampus and the Amygdala in response to stress in Juvenility and Adulthood -Reflection of behavioral individual differencesHadad O. 1,2,3 and Richter-Levin G. 1,2,3,41 Neurobiology and Etiology Department, University of Haifa, Israel; 2 The Brain and Behavior Research Center, Israel; 3 The Institute for the Study of Affective Neuroscience(ISAN); 4 Psychology Department, University of Haifa, Israel16. Exposure to stress differentially affects behavior and brain activity in male and female ratsHorovitz O. 1,2 , Strominger I. 3 , Ashkenazi-Karni S. 1,3 and Richter-Levin G. 1,2,3,41 The Brain and Behavior Research Center, University of Haifa; 2 The Institute for the Study of Affective Neuroscience (ISAN); 3 Neurobiology and Ethology Department, University ofHaifa, Israel; 4 Psychology Department, University of Haifa, Israel17. Behavioral, molecular and morphological responses to continuous versus intermittent intense stress-exposure in an animal model of PTSDCohen H. 1 , Kozlovsky K. 1 , Matar M.A. 1 , Ostfeld . 2 and Kaplan Z. 11 Beer-Sheva Mental Health Center, Ben-Gurion University of the Negev; 2 IDF Southern Command, Medical CorpsAffective &Anxiety Disorders I18. Lithium attenuates depressive-like symptoms in the forced swim test in female offspring of dams that were exposed to early post-natal immunestimulationAlbelda N., Joel D. and Weiner I.Tel-Aviv University, Psychology Department, Tel-Aviv, Israel5

19. Modeling manic behavior in rats: implication of the gene-environmental interaction hypothesisAsor E. 1 , Klein E. 1 , Avital A. 2 and Ben shachar D. 11 Lab of Psychobiology, Dept of Psychiatry, B.Rappaport Faculty of Medicine, Technion, ITT and Rambam; 2 B.Rappaport Faculty of Medicine, Technion, ITT and Emek MedicalCenter20. Effects of 5HT2B serotonin receptor antagonist on conventional and herbal treatment for depressionBrener Y. 1 , Rehavi M. 2 and Doron R. 11 Department of Education and Psychology, The Open University, Israel; 2 Department of pharmacology, Tel-Aviv University, Tel-Aviv, Israel21. Neurochemical characterization of the SMIT1/IMPA1 knockout mice in search for common changes with lithium-treated WT miceDamri O., Agam G. and Belmaker R.Department of Clinical Biochemistry and Psychiatry Reaserch Unit, Faculty of Health Sciences, Ben-Gurion University of the Negev, and Mental Health Center of Beer Sheva, Israel22. Rasagiline (MAO-B inhibitor) prevents neurodegeneration in thiamine deficient rats-a longitudinal MRI and 1H-NMR studyDror V. 1 , Eliash S. 1 , Biton I. 2 and Rehavi M. 11 Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University; 2 Department of Chemical Research Support MR Center, The Weizmann Institute ofScience, Rehovot23. Adaptogens treatment for anxiety in comparison to SSRI: high efficacy with minimum side-effectsEinat N. 1 , Wiener A. 1 , Rehavi M. 2 and Doron R. 1,1 Dept. of Behavioral Science, The Academic Col. of Tel-Aviv Yaffo, Tel-Aviv Yaffo, Israel; 2 Dept. of pharmacology, Tel-Aviv University, Tel-Aviv, Israel; 3 The Open University, Ranna,Israel24. Incensole acetate's reduction of depressive-like behavior and corticosterone levels of submissive animals is accompanied by modulation of CRFand BDNF gene expressionGross M. 1,2,3 , Moussaieff A. 1 , Nesher E. 1,2 , Tikhonova T. 1 , Yadid G. 2 and Pinhasov A. 1,31 Ariel University Center of Samaria; 2 Bar Ilan University; 3 Samaria and Jordan Rift Research and Development Center25. Reduced expression levels of the Ahi1 gene are associated with decrease in state anxiety- threat detection behavior in mutant miceLifschytz T., Lotan A., Zozulinsky P., Greenbaum L. and Lerer BBiological Psychiatry Laboratory, Hadassah Ein Karem Medical Center, Jerusalem 91120, Israel26. A Novel Herbal Treatment for Depression and Anxiety DisordersLotan D. 1 , Yaffe R. 2 , Rehavi M. 3 and Doron R. 1, 21 The Open University, Ranna, Israel; 2 Dept. of Behavioral Science, The Academic Col. of Tel-Aviv Yaffo, Tel-Aviv Yaffo, Israel; 3 Dept. of pharmacology, Tel-Aviv University, Tel-Aviv,Israel27. The time-dependent effects of antidepressants on mRNA expression of the PACAP signaling systemNesher E. 1,2 and Pinhasov A. 11 Ariel University Center of Samaria, Ariel, Israel; 2 Bar Ilan University, Ramat Gan, Israel28. Geriatric Bipolar Disorder Patients'' Cognitive Functioning: Comparison with Unipolar Depressed Patients and Healthy ControlsOmer E. 1 , Ravona-Springer R. 2 , Gal G. 1 and Braw Y. 31 School of Behavioral Sciences, Tel Aviv-Yaffo Academic College, Tel Aviv, Israel.; 2 Tel-Hashomer Psychiatric Outpatient Clinics, Sheba Medical Center, Ramat Gan,Israel.; 3 Department of Behavioral Sciences, Ariel University Center of Samaria, Ariel, Israel6

Schizophrenia I29. Seeking schizophrenia causative variants in large multiply-affected Israeli familiesAlkelai A. 1,2 , Olender T. 1 , Ben-Asher E. 1 , Lancet D. 1 and Lerer B. 21 Dept. of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel; 2 Biological Psychiatry Laboratory, Dept. of Psychiatry, Hadassah - Hebrew University Medical Center30. High circulatory titers of Platelet associated Auto-Antibodies in childhood onset schizophreniaEbert T. 1,2 , Schechtman . 3 , Ram A. 1,2 , Kosov I. 1,2 , Saisky Y. 1,2 ,Weizman A. 2,4,5 , Spivak B. 1,2 and Shinitzky M. 31 Beer Yaakov - Ness-Ziona Mental Health Center; 2 Department of Psychiatry, Sackler Faculty of Medicine, Tel Aviv University; 3 Department of Biological Chemistry, The WeizmanInstitute of Science, Rehovot. ; 4 Geha Mental Health Center, Petah Tikva,; 5 5Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Beilinson Campus31. Evidence for alteration in behavioral parameters associated with decreased brain BDNF,GSK-3-beta and GAD67 expression in DISC1 mice, amouse model of SchizophreniaKaminitz A. 1 , Barzilay R. 2 , Taler M. 1 , Segal H. 2 , Gil-Ad I. 1 , Offen D. 2 and Weizman A. 1,31 Laboratory of Biological Psychiatry, Felsenstein Medical Research Center Tel-Aviv University; 2 Neuroscience Laboratory, Felsenstein Mediacal Research Center, Tel-Avivuniversity, Petah Tikva; 3 Research Unit, Geha Mental Health Center, Petah Tikva, Israel32. Diffusion Tensor Imaging for Catatonic and Non-Catatonic Schizophrenia PatientsKrivoy A. 1,2 , Hoffman C. 2,3 , Avrahami M. 1 , Fischel T. 1,2 , Last D. 4 ,Guez D. 4 and Mardor Y. 2,41 Geha Mental Health Center, 2 Sackler''s School of Medicine, Tel-Aviv University, 3 Radilogy Department, Sheba Medical Center; 4 Advanced Technology Center, Sheba Medical Center33. Adjunctive bexarotene versus placebo for schizophrenia and schizoaffective patients: a 6-week, randomized, placebo-controlled double-blind,multicenter trialLerner V. 1 , Miodownik C. 1 , Gibel A. 2 , Sirota P. 3 , Bush I. 1 , Elliot H. 3 ,Benatov R. 3 and Ritsner M.S. 2,41 Be''er Sheva Mental Health Center, Faculty of Health Sciences Ben-Gurion University of the Negev; 2 Sha’ar Menashe Mental Health Center, Hadera, Israel; 3 Abarbanel MentalHealth Center, Bat Yam, Israel; 4 Department of Psychiatry, the Rappaport Faculty of Medicine, Technion-Israel Institute of Technology34. Voluntary exercise restores the social recognition impairment in dominant-negative DISC1 mice: Implication for schizophreniaSegal H., Barzilay R. and Offen D.Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel-Aviv UniversityLearning and memory35. The role of the medial prefrontal cortex in consolidation of recent and remote extinction memories of conditioned odor aversion and fear conditioningAwad W., Ferreira G. and Maroun M.1 Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa 31905.; 2 Nutrition, Inflammation, Cognition - UMR INRA 1286 - CNRS 5226 - UniversityBordeaux 2, Bordeaux ; 3 Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa 3190536. Orienting bias moderates the association between reinforcement learning and DAT1 polymorphismsBraun Y.R. 1 , Edelman S. 2 , Ebstein R.P. 3, 4 , Gluck M.A. 5 and Tomer R. 11 Department of Psychology, University of Haifa, Israel; 2 Neurobiology Department, Hebrew University, Jerusalem, Israel; 3 Psychology Department, Hebrew University, Jerusalem,Israel; 4 Psychology Department, National University of Singapore, Singapore; 5 Center for Molecular and Behavioral Neuroscience, Rutgers University, USA37. Executive functioning among patients with Borderline Personality Disorder (BPD) and their relativesGvirts H.Z. 1,2 , Harari H. 1,2 , Braw Y. 1,3 , Shefet D. 1,2 , Shamay-Tsoory S.G. 4 and Levkovitz Y. 1,21 The Emotion-Cognition Research Center, Shalvata Mental Health Care Center, Hod-Hasharon, Israel, af; 2 Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv,Israel; 3 Department of Behavioural Sciences, Ariel University Center of Samaria, Israel; 4 Department of Psychology, University of Haifa, Haifa38. The Rational-Choice Theory of Neurosis: A Challenge to the Biological TheoryRofe Y Bar-Ilan university7

אולם יסמין Symposium 9Cellular plasticity in the treatment ofaffective disorders: new perspectivesand possible targetsChairs: Galila Agam & Haim EinatNeurogenesis is not required for lithium'smood stabilizing-like effects: implications forlithium’s therapeutic mechanism of actionKara N. Ben-Gurion University of the NegevBeclin-1 mediate autophagyPinkas-Kramarsky R. Tel-Aviv UniversityAutophagy enhancement: a possible new drugtarget for affective disordersEinat H. Tel Aviv-Yaffo College11:30-13:00אולם אורן Symposium 8 2Child psychiatry: advantages anddisadvantages of animal modelsChairs: Yuval Bloch & Dany SteinAnimal model in gene environment and timinginteraction in adolescent depressionZaltsman G. Tel Aviv University, Geha MHCThree stage model: from increased fear of lifeto increased attraction towards death toincreased suicidallity in female adolescenteating disorder inpatientsStein D. Tel Hashomer and Sackler Faculty ofMedicine, Tel Aviv UniversityEnvironmental Enrichment Preceding EarlyAdulthood Methylphenidate Treatment Leadsto Long Term Increase of Corticosterone andTestosterone in the RatAvital A. Rappaport Faculty of Medicine,Technion and Emek Medical CenterMethylphenidate causes a significant reductionin state anxiety during a continuousperformance test that typifies ADHD patientsfrom controlsBloch Y. Shalvata Mental Health Center, andSackler Faculty of Medicine, Tel Aviv Universityאורן Symposium 7 1The role of oxytocin and argininevasopressin in schizophreniaChairs: Ilana Kremer & Raz LevinOxytocin in the etiology and treatment ofschizophreniaKohn Y. Hadassah Hospital Ein Kerem,JerusalemThe association between oxytocin receptor(OXTR) and prepulse inhibition in healthysubjectsLevin R. Herzog Hospital JerusalemSex specific effect of intranasal oxytocinand vasopressin on emotional recognitionand perception in schizophrenia patientsBloch B. Ha'Emek Medical Center13:00-14:00 ארוחת צהריים בלובי ותצוגת חברות10

60. Cannabinoid receptor agonist administered in the aftermath of trauma followed by repeated exposure to situational reminders amelioratetraumatic fear retrievalWeinshtok N. and Akirav I.University of Haifa, Department of PsychologyAffective & Anxiety Disorders II61. Deep TMS for Treatment Resistant Depression: A 22-Week Add-on Safety and Feasibility StudyRabany L. 1,2,3 , Harel E. . 1 , Deutsch L. 4 , Bloch Y. 1,2 and Zangen A. 51 The Emotion-Cognition Research Center, Shalvata Mental Health Care Center, Hod-Hasharon, Israel; 2 Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel; 3 GordonFaculty of Social Sciences, Tel-Aviv University, Israel; 4 Biostats, Israel. ; 5 Department of Neurobiology, The Weitzman Institute of Science, Rehovot, Israel62. The Mesopontine Rostromedial Tegmentum (RMTg), a negative modulator of dopamine, as a novel target for intervention in depressive-like behaviorRedlus L. 1, 2 , Barnea R. 1, 2 , Fridman-Damti E. 2 , Marco A. 1, 2 , Weller A. 1, 3 and Yadid G. 1, 21 The Gonda Brain Research Center University of Bar-Ilan University Ramat-Gan, Israel; 2 The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University Ramat-GanIsrael; 3 Psychology Department, Bar-Ilan University Ramat-Gan Israel63. Behavioral effects and c-Fos expression patterns of exposure to reminder cue of traumatic experienceRitov G. 1 and Richter-Levin G. 1,21 The Institute for the Study of Affective Neuroscience (ISAN), University of Haifa; 2 The Brain and Behavior Research Center, University of Haifa64. The effect of Lithium on brain inositol turnoverSade Y. 1,2 , Belmaker R.H. 2 and Agam G. 1.21 Department of Clinical Biochemistry Faculty of Health Sciences, Ben-Gurion University of the Negev; 2 Psychiatry Research Unit Mental Health Center, Beersheva, Israel65. The potential role of cannabinoid receptor activation in treating stress-induced depression in adult ratsSharabi A. and Akirav I.Department of Psychology, University of Haifa66. Dissociation between the roles of BDNF in the antidepressant effects of electroconvulsive treatment and desipramineTaliaz D. 1 , Nagaraj V. 1 , Haramati S. 1 , Chen A. 1 and Zangen A. 21 Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel; 2 Department of Life Science, Ben Gurion University, Beer Sheva, Israel67. Effect of chronic lithium treatment on IMPA1 and BDNF short/long mRNA ratioToker L. 1,2 , Belmaker R. 2 and Agam G. 1,21 Department of Clinical Biochemistry, Ben-Gurion University of the Negev, Beer Sheva, Israel; 2 Psychiatry Research Unit and Mental Health Center, Ben-Gurion University, BeerSheva, Israel68. Differentiating between state and trait anxiety in a genetic mouse model with reduced Abelson Helper Integration Site 1 (AHI1) gene expressionZozulinsky P., Lotan A., Lifschytz T. and Lerer B.Biological Psychiatry Laboratory, Hadassah Ein Karem Medical Center, Jerusalem 91120, Israel.69. Comparison of cognitive function in bipolar depression versus major depressive disorderErez G. 1,2 , Braw Y. 1 , Bloch Y. 1,2 and Levkovitz Y. 1,21 The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon; 2 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel70. Prospective, systematic evaluation of the psychological effect of ICD implantationAmiaz R. 1,3 , Guy R. 2''3 , Elad A. 2,3 , Hava G. 2,3 , David L. 2''3 , David B. 2,3 , David G. 2,3 , Elena G. 1 , Mark W. 1''3 and Michael G. 2,31 Psychiatry Devision - The Chaim Sheba Medical Center ; 2 Sackler Faculty of Medicine, Tel Aviv University; 3 Leviev Heart Center – The Chaim Sheba Medical Center13

71. Studying the behavioral and biochemical effects of antibiotic treatment in a rat model of GAS-related neuropsychiatric disordersLotan D. and Joel D.Behavioral Neuroscience, Department of Psychology, Tel Aviv University,Tel Aviv, IsraelSchizophrenia II72. Irregularities of event-related magnetic fields in schizophrenia patients with predominant negative symptomsYefet K. 1 , Goldstein A. 2 , Rabany L. 1 and Levkovitz . 11 Cognitive and Emotional Laboratory, Shalvata Mental Health Center & Sackler Faculty of Medicine,; 2 Department of Psychology & Gonda Brain Research Center, Bar IlanUniversity, Ramat Gan, Israel73. Postmortem brain-donation for research and organ transplantation in schizophrenia: what about patient consent?Greenberg B., Bergman-Levy T. and Strous R.Beer Yaakov Mental Health Center, Beer Yaakov, Israel74. Anhedonia is an important factor of health related quality of life deficit in schizophrenia and schizoaffective disorderLisker A. 1 , Arbitman M. 1 and Ritsner M.S. 1,21 Sha''ar Menashe Mental Health Center; 2 Department of Psychiatry, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology75. Deep-TMS as a Novel Treatment for Negative and Cognitive Symptoms of SchizophreniaRabany -Bensky L. 1,2,3 , Levkovitz Y. 1,2 , Harel E.V. 1 and Zangen A. 41 The Emotion-Cognition Research Center, Shalvata Mental Health Center, Hod-Hasharon, Israel; 2 Sackler Faculty of Medicine, Tel-Aviv University, Israel; 3 Gordon Faculty of SocialSciences, Tel-Aviv University, Israel; 4 Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel76. Quality of life deficit in schizophrenia is associated with mental health needs: Findings from a 10-year follow up studyRitsner M.S.1 Department of Psychiatry, Rappaport Faculty of Medicine, Technion -Israel Institute of Technology; 2 Sha''''ar Menashe Mental Health Center, Israel77. Behavioral characterization of mice harboring a complete or targeted mutation of Erbb4 receptorShamir . 1,2 , Karavanov I. 1 , Vullhorst D. 1 and Buonanno A. 11 Section on Molecular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Hum; 2 The Neuroscience Research Lab, Mazra Mental Health Center, Akko78. Does the internet offer social opportunities for individuals with schizophrenia? A cross-sectional pilot studySpinzy Y. 1 , Nitzan U. 1,2 , Becker G. 1 , Bloch Y. 1,2 and Fennig S. 1,21 Shalvata mental health center, Hod-Hasharon, Israel; 2 Sackler School of Medicine, Tel-Aviv University, Israel79. Effect of novel L-DOPA and GABA conjugates on 6-OHDA induced toxicity in-vitro and on Haloperidol-induced catalepsy in-vivoMuravyov A. 1 , Rephaeli A. 2 , Taler M. 1 , Nudelman A. 3 , Tarasenko I. 1 , Weizman A. 4 and Gil-Ad I. 11 Lab of Biological Psychiatry, FMRC and Sackler Faculty of Medicine, Tel Aviv University, Israel; 2 Lab of Pharmacology and Exp. Oncology, FMRC and Sackler Faculty ofMedicine, Tel Aviv University.; 3 Chemistry Department, Bar-Ilan University, Ramat Gan, Israel; 4 Research Unit, Geha Mental Health Center, Petah Tikva, Israel80. Human Hair Follicle Derived Induced Pluripotent Stem Cells (iPSC) and their Differentiation into Dopaminergic Neurons as a Model to StudyNeurodevelopmental Abnormalities in SchizophreniaRobicsek O. 1 , Karry R. 1 , Klein E. 1 , Petit I. 2 , Salman N. 2 , Aberdam D. 2 and Ben-Shachar D. 11 Laboratory of Psychobiology, Department of Psychiatry,Rambam Rappaport Faculty of Medicine,; 2 insertECH, Inserm associated laboratory, Bruce Rappaport Faculty of Medicine,Technion14

אולם Workshop 4Advances in Behavioral Neurogenetics16:00- 17:30Symposium 11 (אולםNew targets to interfere with the rewardsystem- from depression toaddiction and PTSDSymposium 10New insights in functionalconnectivity network models inanimal and human researchאולם יסמיןגולן ‏(ליד המסעדהברושChair: Doron GothelfTemperament of individuals with velo-cardiofacialsyndrome and Williams syndromeSchonherz-Pine Y. Tel-HashomerAssociations between Tourette Syndrome andSensory Modulation DisorderWeisman H. Schneider Children's MedicalCenterReading in Schizophrenic Subjects and theirNon-symptomatic First Degree RelativesGottlob I. University of Leicester, UKWhat can we learn from velo-cardio-facialsyndrome on the effect of COMThaploinsufficiency on brain function and therisk for schizophrenia?Gothelf D. Tel-HashomerChair: Gal YadidUnraveling new targets in the reward circuitryusing rest functional connectivity MRIGoelman G. Hebrew University of JerusalemRole of the ventral tegmental area (VTA) incocaine addictionYaka R. Hebrew University of JerusalemThe lateral habenula - VTA circuit as a newtarget for reward related psychiatric disordersYadid G. Bar-Ilan UniversityChair: Omer BonneRest functional connectivity MRI – Use indepressionGordon N. Hadassah Medical CenterJerusalemDelineating emotional experience bynetwork dynamicsHendler T. Sourasky Medical Center andTel-AvivUniversityRest functional connectivity MRI – Use inPTSDGiesser R. Hadassah Medical CenterJerusalemNew strategy for the choice of DBS targetsbased on functional connectivityGoelman G. Hadassah Hebrew UniversityMedical Center17:30-18:00 הפסקת קפה ותצוגת חברות15

פרסים:‏תחרות עבודת מדעי יסוד:‏תעודת הוקרה מיוחדת:‏פרס האיגוד למנטור מצטייןאולם אורן18:00-20:00 -תעודות הוקרה לחברי ועד פורשים,‏ בחירות לחברי ועד האיגוד החדשיםפרס ראשון מוענק על ידי פרופ'‏ יוסי זהר,‏פרס שני ושלישי מוענק על ידי פרופ'‏ דורון גוטהלף,‏ בחסות חברת דקסל פארמהבחסות ECNPלפרופ'‏ גיל זלצמן - על ההובלה והריכוז של פרוייקט מנהיגות מחקרית צעירה לקלינאים,‏ מוענק על ידי פרופ'‏ אריה שלו‏(מדע קליני)‏מוענק על ידי פרופ'‏ אריה שלוKeynote Speaker: Prof. Dr. Cyril HöschlDirector, Prague Psychiatric Centre & Centre of Neuropsychiatric Studies in PragueProfessor of psychiatry and chairman, 3rd Faculty of Medicine, Charles UniversitySchizophrenia as an information processing disorderIntroduced by: Prof. Arie Shalev20:00 ארוחת ערב21:30 אולם אורן-אחרי ההופעה נפגשים בפאבאריק ברמן בהופעה16

22 במרץ7:00-8:30 ארוחת בוקריום חמישי,‏Workshop 6Basic Science Leadership Program:Inaugural Workshop8:30-10:00Workshop 5Imaging GeneticsSymposium 12Depression and anxiety treatment:from laboratory to clinical practiceאולם יסמיןאולם אורןאולם ברושChair: Arie ShalevProf. Amit EtkinDepartment of Psychiatry and BehavioralSciences, Stanford University School ofMedicine, Stanford UniversityExpanding Opportunities inTranslational ResearchChair: Jonathan RosenblattBasics of genome-wide association studiesGolan D. Tel Aviv UniversityBasics of MRI imagingGilam G. Sourasky Medical CenterMethodologies for associating geneticvariation to imaging attributesRosenblatt J. Tel Aviv UniversityDifficultiesand challenges of such researchLevy O. Tel Aviv UniversityChairs: Uriel Heresco-Levy & Mike MatarHigh dose D-cycloserine for treatmentresistantdepressionHeresco-Levy U. Ezrath-Nashim HerzogMemorial Hospital and Hadassah MedicalSchool, Hebrew University, JerusalemMicroRNAs as endogenous modulators ofserotonergic activityIssler O. Weizmann institute of science, RehovotEarly post-stressor intervention with singledose of Delta-9-tetrahydrocannabinol (THC)is ineffective in preventing posttraumaticstress responses in an animal model for PTSDMatar M.A. Beer-Sheva Mental Health Center,Ben-Gurion University of the Negevאולם אורן 10:00-10:45E-Poster presentations for the best-poster competition IIChairs: Tamar Green, Yuval Bloch and Avi Avital10:45-11:00 הפסקת קפה ותצוגת חברותעד 11:00 פינוי החדרים17

אולם אורן 11:00-11:45Special Symposium: New Horizon, oral presentationsChair: Tamar GreenDifferential expression of genes encoding neuronal ion-channel subunits in major depression, bipolar disorder and schizophrenia:implications for pathophysiologySmolin B Rambam Medical Center and B. Rappaport Faculty of Medicine, Technion, HaifaBNA reveals fm-theta network in a working memory task performed under donepezil and placebo conditionsGeva A.B ElMindA Ltd. Herzliya and Ben Gurion University of the NegevRebelliousness in patients suffering from schizophrenia – a possible predictor of adherenceNitzan U Shalvata Mental Health Center and Tel Aviv UniversityAnger processing among mothers of daughters with binge/purge eating disorders: hemispheric dominanceHason-Rozenstein M University of Haifa and Rambam Medical CenterMononuclear cell gene expression signature of Methylphenidate Response in ADHDGoltser-Dubner T Hadassah Hebrew University Medical centerPath finding in Treatment Resistant Depression: Pioneer Clinical Report of the First DBS (Deep Brain Stimulation) in Depressed Patients in IsraelEitan R Hadassah-Hebrew University Medical Centerאולם אורן 11:45-13:00פרסים לפוסטרים מצטיינים:‏ מוענקים על ידיפרופ'‏ דורית בן שחר ופרופ'‏ גיל זלצמןועדות שיפוט:‏ יום ג':פרופ'‏ דורית בן שחר,‏ פרופ'‏ אהרון ולר,‏ ד"ר תמר גרין,‏ ד"ר יובל בלוך,‏ ד"ר אבי אביטליום ד':‏ פרופ'‏ חיליק לבקוביץ,‏ פרופ'‏ גיל זלצמן,‏ ד"ר תמר גרין,‏ ד"ר יובל בלוך,‏ ד"‏ ר אבי אביטלKeynote Speaker: Prof. Amit EtkinDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford UniversityDisentangling anxiety and mood disorders: a neural circuit viewIntroduced by: Prof. Arie Shalev1813:00-14:00 ארוחת צהרים קלה,‏ מילוי משובים וסיום הכנס