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הכנס השנתי ה - 16 של האיגוד הישראלי לפסיכיאטריה ביולוגית

הכנס השנתי ה - 16 של האיגוד הישראלי לפסיכיאטריה ביולוגית

הכנס השנתי ה - 16 של האיגוד הישראלי לפסיכיאטריה ביולוגית

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Symposium 6The role of cannabis in trauma andanxiety: From basic to clinical studies<strong>16</strong>:00-17:30אולם אורן Symposium 5 2Understanding social behavior inautism: from DNA to social cognition15:30-<strong>16</strong>:00 הפסקת קפה ותצוגת חברות בלוביאולם יסמיןChairs: Irit Akirav and Arie ShalevIntroduction to PTSD and the neuromodulatorsinvolvedShalev A. The Hebrew University of JerusalemPilot open label trial on oral absorbable Δ 9-THC for chronic PTSDRoitman P. Hadassah, Hebrew University MedicalCenter, JerusalemCannabinoids ameliorate PTSD-like symptomsin a rat modelAkirav I. University of HaifaMedical cannabis use in PTSD: a naturalisticobservational studyReznik I. MaReNa Diagnostic and ConsultingCenter, Tel-AvivChairs: Simone Shamay-Tsooryand Yoav KohnDetection and characterization of copynumber variations in Jewish Israeli autisticpatientsKohn Y. Jerusalem Mental Health Center, TheHebrew University of JerusalemBio-Behavioral Synchrony and the Cross-Generation Transmission of SocialAdaptation and PsychopathologyFeldman R. Bar-Ilan UniversitySocial behavior in autismShamay-Tsoory S. University of Haifaאולם אורן Symposium 4 1New attitude for diagnosing andtreating addictionChairs: Gal Yadid and Avi WeizmanUsing genetic and epigenetic markers forbetter diagnosing and treating addictYadid G. Bar-Ilan UniversityEfficient diagnosing substance relateddisordersCarmel Z. Shalvata Mental Health CenterAntioxidants can reverse cocainesensitization and cocaine conditionedrewardYaka R. The Hebrew University ofJerusalemBuprenorphine for Opiate Detoxificationin Dual-Diagnosis Inpatients with ActivePsychosisDelayahu Y. Abarbanel Mental HealthCenterElectromagnetic stimulation of the insularcortex and the prefrontal cortex reducescigarette craving and consumptionZangen A. Ben-Gurion University of theNegev, Beer-Sheva213:71-10:11 הפסקת קפה ותצוגת חברות בלובי


1. Allosteric regulation of neuron-astrocyte interaction in the dentate gyrus in an animal model of post traumatic stress disorderAlbrecht A. 1, 2, 3 , Ivens S. 4, 5 , Heinemann U. 5 , Richter-Levin G. 2, 3 and Stork O. 11 Institute of Biology, Otto-von-Guericke-University Magdeburg, Germany ; 2 Department of Neurobiology and Ethology & Department of Psychology, University of Haifa, Israel; 3 The Institutefor the Study of Affective Neuroscience (ISAN), Haifa, Israel; 4 Department of Psychiatry and Psychotherapy, Charit?-Universit?tsmedizin Berlin, Germany; 5 Institute for Neurophysiology,Charit?-Universit?tsmedizin Berlin, Germany;2. ''Enriched Environment'' in either juvenility or adulthood prevents the effects of ''Juvenile stress'' model of PTSD, when examined with a reminderof the adulthood stressful experience.Ardi Z. 1,4 , Richter-Levin A. 3 and Richter-Levin G. 1,2,41 Neurobiology and Etiology Department, University of Haifa. Israel.; 2 Department of Psychology, University of Haifa. Israel.; 3 Department of Biology, University of Haifa. Israel.; 4 TheInstitute for the study of Affective Neuroscience, University of Haifa. Israel.;3. Categorization of male rats after stress exposure to affected and non affected by behavioral criterions and expression of KAPPA opioid and GABA-AreceptorsAshkenazi-Karni S. 2,3 , Metzger N. 1,2 , Vered R. 1,2 and Richter levin G. 1,2,31 Psychology Department, University of Haifa, Israel; 2 The Institute for the Study of Affective Neuroscience (ISAN); 3 Neurobiology and Etiology Department, University of Haifa, Israel;4. Dorsal Periaqueductal gray (dPAG) modulation of plasticity in the Nucleus Accumbens (NAcc) and the Basloateral Amygdala (BLA) induced byVentral Subiculum (vSub) stimulationHorovitz O. 2,3 and Richter-Levin G. 1,2,3,41 Psychology Department, University of Haifa, Israel; 2 The Brain and Behavior Research Center, Israel; 3 The Institute for the Study of Affective Neuroscience (ISAN); 4 Neurobiology andEtiology Department, University of Haifa, Israel;5. Seeking schizophrenia causative variants in Israeli familiesAlkelai A. 1 , Olender T. 1 , Ben-Asher E. 1 , Lancet D. 1 and Lerer B. 21 Dept. of Molecular Genetics, Weizmann Institute of Science, Rehovot; 2 Biological Psychiatry Laboratory, Dept. of Psychiatry, Hadassah - Hebrew University Medical Center;6. A role for GAD 65 in the Ventral Hippocampus in mediating anxiety and in learning under stressAlgon R. 1235 , Anunu R. 125 , Levin G.R. 123 , Stork O. 4 and Mueller B. 41 The Institute for the Study of Affective Neuroscience (ISAN), University of Haifa, Haifa, Israel; 2 The Brain and Behavior research Center, University of Haifa, Haifa, Israel; 3 Department ofNeurobiology and Etiology, University of Haifa, Haifa, Israel ; 4 department of genetics & molecular neurobiology,, Otto-von-Guericke University Magdeburg Germany; 5 Equal contribution;7. The Long-Term Effects of Substance Abuse on Cognition and Emotion Recognition: A Case-Control StudyAmit B.H. 1,2 , Mell H. 3 , Roshka P. 3 , Dadon R. 4,5 , Aizner R. 4 and Shoval G. 1,21 Geha Mental Health Center, Research Unit, Petach Tiqva, Israel; 2 Sackler Faculty of Medicine, Tel Aviv University, Israel; 3 Israeli Ministry of Health, Jerusalem; 4 Malkishua RehabilitationCenter, Gilboa, Israel; 5 Department of Social Work, Haifa University, Israel;8. The Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Quantitative EEG Measures in Major Depressive DisorderAmiaz R. 1''2 , Kogan E. 2 and Grunhaus L. 31 The Chaim Sheba Medical Center; 2 Tel Aviv University; 3 Jerusalem Psychiatric Center;9. A new combined treatment for re-experiencing, avoidance and hyper-arousal in a PTSD-like animal modelAga- Mizrachi S. 1 , Cymerblit-Sabba A. 1 , Zubedat S. 1 and Avital A. 1,21 Bruce and Ruth Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israe; 2 mek Medical Center, Afula, Israel ;4


10. The Effects of Parental Exposure to Escitalopram or to a Novel Herbal Treatment on the Expression of Serotonin Transporter in the Brain ofOffspring MiceArmoza S. 1 , Atrakchi D. 2 , Doron R. 2,3 and Rehavi M. 11 Dept. of physiology & Pharmacology, Sackler Faculty of Medicine , Tel-Aviv University; 2 Dept. of Behavioral Science, The Academic Col. of Tel-Aviv Yaffo; 3 Dept. of Education andPsychology, The Open University;11. Daily rhythm of Brain-derived neurotrophic factor in hippocampus, frontal cortex and serum of the diurnal fat sand rat maintained under natural orshort photoperiodAshkenazy frolinger T. 1 , Einat H. 2 and Kronfeld-Schor N. 11 Dept. of Zoology, Tel-Aviv University; 2 School of Behavioral Sciences,Tel Aviv-Yaffo Academic College;12. Transient interference with the ubiquitous transcription factor Sp1 leads to disparate behavioral response to sub-chronic and chronic stressAsor E. 1 , Belhanes H. 2 , Kavushansky A. 1 , Zubedat S. 2 , Klein E. 1 , Avital A. 2 and Ben-Shachar D. 11 Laboratory of Psychobiology, Department of Psychiatry, Rambam Medical Center and B. Rappaport Facul; 2 Rappaport Faculty of Medicine, Behavioral Neuroscience Lab, Technion andEmek Medical Center;13. The effects of prenatal exposure to escitalopram compared with novel herbal treatment on offspring developmentAtrakchi D. 1 , Ashuah-Schneider S. 1 , Rehavi M. 2 and Doron R. 1,31 Dept. of Behavioral Science, The Academic Col. of Tel-Aviv Yaffo; 2 Dept. of Physiology and Pharmacology ,Sackler Faculty of Medicine, Tel-Aviv University; 3 Dept. of Education andPsychology, The Open University;14. Early post-stressor intervention with alcohol in an animal model for PTSDAsraf O. 1 , Kozlovsky N. 2 , Kaplan Z. 2 and Cohen H. 21 Gonda Multidisciplinary Brain Research Center, Bar-Ilan University; 2 Beer-Sheva Mental Health Center, , Faculty of Health Science Ben-Gurion University of the Negev;15. The role of CD44 signaling in response to stress in mice and in suicidal behavior in humansBarzilay R. 1,2 , Ventorp F. 3 , Segal H. 1 , Aharoni I. 1 , Globus R. 1 , Weizman A. 2 , Naor D. 4 , Lipton J. 5 , Traskman-Bendz L. 3 , Offen D. 1 and Brundin L. 51 Neurosciences lab, Felsenstein Medical Research Center, Tel Aviv University, Petach-Tikva, Israel; 2 Research Unit at Geha Mental Health Center, Tel Aviv University, Petach-Tikva,Israel; 3 Psychoimmunology Unit, Division of Psychiatry, Lund University, Lund, Sweden; 4 Lautenberg Center for Immunology, The Hebrew University, Jerusalem, Israel; 5 Dept. ofTranslational Science & Molecular Medicine, Michigan State University, Grand Rapids, MI, US;<strong>16</strong>. PANDAS - Can We Reach a Final Verdict: The EMTICS StudyBenaroya-Milshtein N. 1 , Steinberg T. 1 , Ruhrman D. 1 , Gev E. 1 and Apter A. 1The Matta and Harry Freund Neuropsychiatric Tourette Clinic, Psychological Medicine, SCMCI;17. Impaired assembly of the first complex of the respiratory chain as a possible cause for mitochondrial dysfunction in schizophreniaBergman O. 1 , Karry R. 1 and Ben-Shachar D. 1Laboratory of Psychobiology, Rambam Health Care Campus, department of medicine, Technion Institute;18. Brain cancer. The 18 kDa Translocator Protein (TSPO) affects gene expression associated with the cell cycle in U118MG glioblastoma cells as studiedwith TSPO knockdown and ligandsBode J. 1 , Veenman L. 2 , Kugler W. 1 and Gavish M. 21 Department of Pediatrics, Haematology and Oncology, University Medical Center, Goettingen, Germany; 2 Technion-Israel Institute of Technology, Faculty of Medicine, Haifa, Israel;19. Herbal treatment increases circulating levels of Interleukin-1 in ICR miceCohen R. 1 , Nave T. 1 , Eyal N. 1 , Avitsur R. 1 and Doron R. 1,21 Dept. of Behavioral Science, The Academic Col. of Tel-Aviv Yaffo; 2 Dept. of Education and Psychology, The Open University5


20. The effects of natural inactive phase sleep deprivation on active phase stress exposure in rats model for PTSDCohen S. 1,2 , Kozlovsky N. 2 , Kaplan Z. 2 , Zohar J. 3 and Cohen H. 1,21 Department of Psychology, Ben-Gurion University of the Negev, Beer Sheva; 2 Anxiety and Stress Research Unit, Ministry of Health Mental Health Center,Beer Sheva; 3 The Chaim ShebaMedical Center, Tel-Aviv University;21. Inheritance of maternal stress-induced RNA editing changes in ratsZaidan H. 1 , Golumbic Y. 1 , Leshem M. 1 and Gaisler-Salomon I. 1Department of Psychology, University of Haifa, Israel;22. Methylphenidate modifies attentional bias in healthy individualsDorman S. 1 , Gelbard H. 1 , Segev A. 2 , Feffer K. 2 , Gvirts H. 2 , Levkovitz Y. 2 , Barnea Y. 2 , Lewis Y.D. 2 and Tomer R. 11 Dept. of Psychology, University of Haifa; 2 The Emotion-Cognition Research Center, Shalvata Mental Health Care Center, Hod-Hasharon;23. Association between orienting bias, risk taking behavior and DAT1 polymorphismsEilat N. 1 , Braun Y. 1 , Koren O. 1 , Ben Shimol L. 1 and Tomer R. 1Department of psychology, Haifa University;24. Sex is not a factor in the manic-like behavior of Black Swiss miceEne H.M. 1, 2 , Kara N.Z. 2, 3 and Einat H. 2, 41 Dep. of Psychobiology, School of Psychological Sciences, Tel-Aviv University, Tel-Aviv, Israel; 2 School of Behavioral Sciences, Tel Aviv-Yaffo Academic College, Tel-Aviv, Israel; 3 Dep. ofClinical Biochemistry, Ben-Gurion University of the Negev, Beersheba, Israel; 4 College of Pharmacy, University of Minnesota, USA;25. The relation between stress and tic suppression ability in children with Tourette syndrome and other tic disordersFriling M. 1,3 , Pilowsky Peleg T. 2,3 , Apter A. 1 and Steinberg T. 11 Matta and Harry Freund Neuropsychiatry Tourette Syndrome and Tic Disorders Clinic; 2 The Neuropsychological Unit,Schneider Childrenâ€s Medical Center; 3 Tel Aviv-Yaffo AcademicCollege ;26. Differential effects of Methylphenidate on risk-taking in healthy individualsGelbard H. 1 , Eilat N. 1 , Dorman S. 1 , Zozulinsky P. 1 , Tkach L. 1 , Segev A. 2 , Feffer K. 2 , Gvirts H. 2 , Levkovitz Y. 2 , Barnea Y. 2 , Lewis Y.D. 2 and Tomer R. 11 Department of Psychology, University of Haifa; 2 The Emotion-Cognition Research Center, Shalvata Mental Health Care Center, Hod-Hasharon;27. Safety signals in the primate amygdalaGenud Gabai R. 1 , Klavir O. 1 and Paz R. 1Department of Neurobiology, Weizmann Institute of Science, Rehovot;28. Effects of the Anti-Multiple Sclerosis Agent Laquinimod on Anxiety and Depression in Rodent Behavioral Models: Possible Role of Brain BDNFGil-Ad I. 1,2 , Amit B.H. 2,3 , Hayardeni L. 4 , Tarasenko I. 1,2 , Taler M. 1,2 , Birnberg T. 4 , Uzan-Gueta R. 1,2 and Weizman A. 1,2,31 Felsenstein Medical Research Center, Biological Psychiatry Lab., Rabin Medical Center, Petach Tikva; 2 Sackler Faculty of Medicine, Tel Aviv University, Israel; 3 Geha Mental HealthCenter, Research Unit, Petach Tikva, Israel; 4 Teva Pharmaceutical Corporation, Israel;29. Acceptance of premonitory urges and TicsGev E. 1 , Tilowski Peleg T. 2 , Steinberg T. 1 and Apter A. 11 Matta and Harry Neuropsychiatry Tourette Syndrome and Tic Disorder Clinic; 2 Tel Aviv-Yafo Academic College ;30. Comparative effect of the antipsychotic drug Olanzapine and its novel analog PGW5 on metabolic parameters associated with therapy in female ratmodelGlobus R. 1 , Vered I. 2 , Taler M. 1 , Shbiro L. 2 , Gil-Ad I. 1 , Weller A. 2 and Weizman A. 1,31 Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Tel-Aviv University.; 2 Department of Psychology, Bar-Ilan University.; 3 Research Unit, Geha Mental HealthCenter, Petah Tikva, Israel.6


41. MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy and intact serotonergic activityIssler O. 1 , Harmati S. 1 , Paul E. 2 , Maeno H. 3 , Navon I. 1 , Zwang R. 1 , Gil S. 1 , Awatramani R. 4 , Binder E. 5 , Deneris E. 3 , Lowry C. 2 and Chen A. 11 Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel; 2 Department of Integrative Physiology and Center for Neuroscience, University of Colorado BoulderUSA; 3 Case Western Reserve University, School of Medicine, Cleveland, OH, USA; 4 Department of Neurology and Center for Genetic Medicine, Northwestern University, Chicago,USA; 5 Max-Planck Institute of Psychiatry, Munich, Germany;42. Post Myocardial Infaction Depressive Symptoms in Israel: A Cross-Sectional AnalysisHussein A. 1 , Amit B.H. 2 , Rozman V. 3 , Shugaev I. 4 and Marmor A. 51 Department of Emergency Medicine, Ziv Medical Center, Zefat, Israel; 2 Research Unit, Geha Mental Health Center, Petach Tiqva, Israel; 3 Department of Psychiatry, Ziv Medical Center,Zefat, Israel ; 4 Department of Internal Medicine, Carmel Medical Center, Haifa, Israel; 5 Department of Cardiology, Ziv Medical Center, Zefat, Israel;43. Autophagy enhancement and antidepressant-like effects of trehalose in mice: possible relevance to autophagy enhancementKara N.Z. 1,2,3 , Toker L. 2,3 , Agam G. 2,3 , Anderson G. 4 , Belmaker R. 3 and Einat H. 1,41 School of Behavioral Sciences, Tel Aviv-Yaffo Academic College, Tel-Aviv, Israel; 2 Department of Clinical Biochemistry, Ben-Gurion University of the Negev, Beersheba, Israel; 3 PsychiatryResearch Unit, Ben-Gurion University of the Negev, Beersheba, Israel; 4 College of Pharmacy, University of Minnesota, USA;44. Intracerebroventricular transplantation of human mesenchymal stem cells increases brain BDNF levels and improves three core autistic-likebehavioural phenotypes of BTBR miceKarvat G. 1 , Segal H. 2 , Barzilay R. 2 , Ganz J. 2 , Edri L. 1 , Offen D. 2 and Kimchi T. 11 Department of Neurobiology, Weizmann Institute of Science; 2 Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel-Aviv University;45. Early post-stress microinfusion of SiRNA-192/194 cluster regulates the Period gene family into the dorsal hippocampus in an animal model of PTSDKoresh O. 1 , Kozlovsky N. 1 , Kaplan Z. 1 , Zohar J. 2 and Cohen H. 11 Beer-Sheva Mental Health Center, Faculty of Health Sciences, Ben-Gurion University of the Negev ; 2 Division of Psychiatry, The State of Israel Ministry of Health, The Chaim Sheba MedicalCenter;46. Subjective experience and attitudes towards specific antipsychotic-related adverse effects in schizophrenia patientsKrivoy A. 1,2 , Fischel T. 1,2 , Kotlarov M. 2 , Jacoby H. 1 , Loebstein O. 1 , Zemishleny Z. 1,2 and Weizman A. 1,2,31 Geha Mental Health Center, Petach-Tikva; 2 Sackler Faculty of Medicine, Tel-Aviv Univeristy; 3 Felsenstein Medical Research Center, Petach-Tikva;47. Beyond the HPA-axis: the role of the gonadal steroid hormone receptors in modulating stress-related responses in an animal model of PTSDKozlovsky N. 1 , Zohar J. 2 , Kaplan Z. 1 and Cohen H. 11 Beer-Sheva Mental Health Center, Ben-Gurion University of the Negev; 2 The Chaim Sheba Medical Center, Tel-Aviv University;48. Oxytocinergic manipulations in corticolimbic circuit differentially affect fear acquisition and extinctionLahoud N.E. 1,2,3 and Maroun M. 1,2,31 Sagol Department of Neurobiology; 2 Faculty of Natural Sciences; 3 University of Haifa;49. Rapid synaptic changes occur during cue-induced relapse to cocaine and nicotineKupchik Y.M. 1 , Gipson C.D. 1 and Kalivas P.W. 1Department of Neurosciences, Medical University of South Carolina, Charleston SC, USA;50. Pathway to disordered eating encompasses self critical perfectionism and genetic variation in DAT1 and COMT : Results from structural equationmodelingLevin K.S. 1 , Alkalai A. 1 , Greenbaum L. 1 , Rigbi A. 1 , Berry E. 2 and Lerer B. 11 Biological Psychiatry Laboratory, Hadassah Medical Center, Ein Karem, Jerusalem ; 2 Department of Metabolism and Nutrition, Hadassah Medical Center, Ein Karem, Jerusalem;51. Neural Correlates of Emotional Intelligence: An Event-Related Potentials (ERP) StudyRaz S. 1,2 , Dan O. 1 and Zysberg L. 21 Department of Psychology, The Center for Psychobiological Research, Yezreel Valley College; 2 Department of Psychology, Tel Hai College;8


52. The association between cannabis use and depression: a meta-analysis of longitudinal studiesLev-Ran S. 1,2 , Roerecke M. 2 , Le Foll B. 2,3 , George T. 2,3 , McKenzie K. 2,3 and Rehm J. 2,3,41 Addiction Medicine Services, Department of Psychiatry, Sheba Medical Center, Tel Hashomer, Israel; 2 Centre for Addiction and Mental Health, Toronto, ON, Canada; 3 University ofToronto, Toronto, ON, Canada; 4 Technische Universitat Dresden, Dresden, Germany;53. Dominant and Submissive mice show differential expression of genes involved in regulation of the HPA axis and different pattern of synapticplasticity in the hippocampusNesher E. 1,2 , Gross M. 1,3 , Lisson S. 1,2 , Sadvakassova G. 1,4 , Sheinin A. 3 , Tikhonov T. 1,2 , Michaelevski I. 3 , Yadid G. 2 and Pinhasov A. 11 Department of Molecular Biology, Ariel University Center, Ariel, Israel; 2 Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel; 3 Department of Biochemistry and MolecularBiology, Tel-Aviv University, Tel-Aviv, Israel; 4 Kazakh National Medical University, Almaty, Kazakhstan;54. What is considered abnormal sustaining of attention? A survey among teachers and parents of elementary school children1 yael segal trivitz; 2 Tal Shani Sherman; 3 Miriam Levav; 4 Doron Gothelf ;55. Physiological and endocrine responses to environmental and visceral stressors indicate diminished stress reactivity of Ahi1 (Abelson helperintegration site 1) gene heterozygous knockout mice.Lifschytz T. 1 , Lotan A. 1 , Slonimsky A. 1 , Greenbaum L. 1 and Lerer B. 1Biological Psychiatry Laboratory, Hadassah- Hebrew University Medical Center, Jerusalem;56. Neural mechanisms underlying stress resilience in the Ahi1 knockout mouse: Relevance to neuropsychiatric disordersLotan A. 1 , Lifschytz T. 1 , Slonimsky A. 1 , Broner E.C. 1 , Greenbaum L. 1 , Abedat S. 2 , Fellig Y. 3 , Cohen H. 4 , Lory O. 5 and Goelman G. 5 and Lerer B. 11 Biological Psychiatry Laboratory, Hadassah-Hebrew University Medical Center, Jerusalem; 2 Cardiovascular Research Center, Hadassah-Hebrew University Medical Center,Jerusalem; 3 Dept of Pathology, Hadassah- Hebrew University Medical Center, Jerusalem; 4 Mental Health Center, Beersheba; 5 MRI Lab, Medical Biophysics, Hadassah-Hebrew UniversityMedical Center, Jerusalem;9


3:11-0:71 ארוחת בוקריום רביעי,‏ 71במרץ8:30- 10:00אולם אורן Symposium 8 2Alternative treatments in psychiatryאולם Symposium 7 1Biology and management of olddementia and Alzheimer's diseaseאורןאולם ברושResearch Presentations of PsychiatryResidents:Chairs: Moshe Rehavi and Alon ReshefOmega3-DHA Treatment of GeneralizedSocial Phobia (GSP): An Open Pilot StudyHeremesh H. Tel Aviv University, Geha MHCNovel Herbal Treatment for AnxietyDisorders: High Efficacy with MinimumSide-EffectsDoron R. The Open University and Tel-Aviv-Yaffo Academic CollegeHypericum perforatum (an herbalantidepressant) as a noncompetitiveinhibitor of biogenic amines uptake in ratbrainRehavi M. Sackler Faculty of Medicine, Tel-Aviv UniversityRethinking the Placebo EffectLichtenberg P. Herzog Memorial Hospital,JerusalemChairs: Amos D. Korczynand Yoram BarakIsraeli consensus criteria on treatment ofdementiaBarak Y. Abarbanel Mental Health Center andthe Sackler Faculty of Medicine, Tel-AvivUniversityWhy have we failed to cure Alzheimer'sdisease?Korczyn A. Tel Aviv UniversityPrevention of dementiaPaleacu D. Abarbanel Mental Health Centerand the Sackler Faculty of Medicine, Tel-AvivUniversity10:00-10:30 הפסקת קפה ותצוגת חברות12


אולם אורן 10:30-11:30Keynote Speaker:Prof. Jim van OsThe Centre of Contextual Neuroscience at Maastricht University Medical Centre, Maastricht, The Netherlands.Negative symptoms of schizophreniaIntroduced by: Prof. Mark WeiserSponsored by ROCHE11:71-17:11אולם אורן 11:71-12:71אולם ברושResearch Presentations of Psychiatry Residents:E-Poster presentations for the best-poster competition-IChairs: Amir Krivoy, Ravid Doron and Avi Avital17:11-11:11 ארוחת צהריים בלובי ותצוגת חברות11


אולם אורן 14:00-15:30Poster Session II & Refreshmentsועדת השיפוט:‏ יו"ר - רונן סגמן.‏ חברים:‏ עומר בונה,‏ גל ידיד,‏ דורית בן שחר,‏ רז ירמיהSponsored by NIPI57. Specificity of Cognitive Deficits in Bipolar Disorder versus Borderline Personality DisorderGvirts H.Z. 1,2 , Braw Y. 3 , Harari H. 1,2 , Shamay-Tsoory S. 4 and Levkovitz Y. 1,21 The Emotion-Cognition Research Center, Shalvata Mental Health Care Center, Hod-Hasharon, Israel.; 2 Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel; 3 Department ofBehavioural Sciences, Ariel University Center of Samaria, Israel; 4 Department of Psychology, University of Haifa, Haifa;58. Development of obesity and anxiety -related behaviors in OLETF rats: Effect of maternal gestational caloric restrictionFrankel N. 1,3 , Pismanyuk T. and Weller A. 2,31 Life Sci Faculty, ; 2 Psychol. Dept, ; 3 Gonda Brain Res Ctr, Bar Ilan Univ, Israel;59. High fat diet induces epigenetic modifications on the POMC promoter affecting obesity in male and female ratsMarco A. 1,2 , Kisliouk T. 4 , Tabachnik T. 1 , Lavi Y. 1 , Eliyahu L. 1 , Meiri N. 4 and Weller A. 1,31 Faculty of Life Sciences; 2 Gonda Brain Res Center; 3 Department of Psychology, Bar Ilan University, Ramat-Gan 52900, Israel. ; 4 Institute of Animal Science, ARO, The Volcani Center, POBox 6, Bet Dagan 50250, Israel.;60. What is expertise in treating depression? The effect of specialty and seniority on the explanation and evaluation of side effects related to SSRI'sNitzan U. . 1, 2 , Becker G. . 1 , Beckerman T. 1 , Fennig S. 1,2 , Lev-Ran S. 1,2 and Bloch Y. 1,21 Shalvata Mental Health Center, 13 Aliyat Hanoar St, Hod Hasharon, 45100, Israel; 2 bSackler School of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel;61. Reduced Oxytocin Levels Among Adolescents with Conduct Disorder and with Callous-Unemotional TraitsLevy T. 1 , Bloch Y. 1 , Bar-Maisels M. 3 , Gat-Yablonski G. 3 , Philip M. 3 , Borodkin K. 4 and Apter A. 21 Shalvata Mental Health Center, Hod Hasharon, Israel.; 2 Feinberg Child Study Center, Schneider Children Hospital, Tel Aviv University, Tel Aviv, Israel.; 3 National Center for ChildhoodDiabetes; Schneider Childrenâ€s Hospital, Tel Aviv, Israel.; 4 Department of Psychology, Bar-Ilan University, Ramat Gan 52900, Israel.62. Gene Environment Interation in depressed and anxious adolescentsOshry N. 1 , Kronenberg S. 1 , Frisch A. 2 , Weizman A. 2 and Apter A. 11 Schneiders Childrens Medical Center; 2 Felsenstein Medical Research Center;63. Get In Touch: The Role of Oxytocin in Social TouchPeled L. 1 , Wagner S. 2 , Perry A. 3 and Shamay-Tsoory S. 41 Dept. of Psychology, University of Haifa, Haifa ; 2 Dept. of Neurobiology and Ethology, University of Haifa, Haifa; 3 Dept. of Psychology, University of Haifa, Haifa ; 4 Dept. of Psychology,University of Haifa, Haifa ;64. Oxytocin Improves Emotion Recognition in PTSDPalgi S. 1,2 , Klein E. 2 and Shamay-Tsoory S.G. 11 Department of Psychology, University of Haifa, Israel.; 2 Department of Psychiatry, Rambam Health Care Campus, Haifa, Israel.;65. PFT-alpha, a p53 inhibitor, ameliorates cognitive impairments after exposing mice to mild traumatic brain injuryRachmany L. 1 , Tweedie D. 2 , Vardit R. 1 , Greig N.H. 2 and Pick C.G. 112


1 Department of Anatomy and Anthropology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, I; 2 Laboratory of Neurosciences, Intramural Research Program, National Institute onAging, National Inst;66. Studying clinical populations using resting state fMRIHahamy A. 1 , Gilaei-Dotan S. 2 , Dinstein I. 3 , Salomon R. 4 , Behrmann M. 3 , Ohana-Berkovich A. 1 , Nir Y. 5 and Malach R. 11 Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel ; 2 Institute of Cognitive Neuroscience, UCL, London, UK; 3 Department of Psychology, Carnegie MellonUniversity, Pittsburgh, USA. ; 4 Laboratory of Cognitive Neuroscience, Brain Mind Institute, EcolePolytechnique F?d?rale de Lausanne ; 5 Department of Psychiatry, University ofWisconsin–Madison, Madison, Wisconsin 53719;67. Effects of stress-exposure on electroencephalogram (EEG) in an animal model of PTSDKoresh O. 1 , Kozlovsky N. 1 , Kaplan Z. 1 , Zohar J. 2 , Geva A. 3 and Cohen H. 11 Beer-Sheva Mental Health Center, Faculty of Health Sciences, Ben-Gurion University of the Negev; 2 Division of Psychiatry, The State of Israel Ministry of Health, The Chaim Sheba MedicalCenter; 3 Department of Electrical and Computer Engineering, Ben-Gurion University of the Negev;68. High dose corticosterone immediately after stress-exposure prevents hippocampal cytoarchitecture and neuronal plasticity damage in an animalmodel of PTSDKozlovsky . 1 , Zohar . 2 , Kaplan . 1 and Cohen . 11 Beer-Sheva Mental Health Center, Ben-Gurion University of the Negev; 2 The Chaim Sheba Medical Center, Tel-Aviv University;69. Behavioral effects and c-Fos expression patterns of exposure to a contextual reminder of underwater traumaRitov G. 1,3 , Boltyansky B. 3 and Richter-Levin G. 1,2,31 Neurobiology and Etiology Department, University of Haifa, Israel; 2 Psychology Department, University of Haifa, Israel; 3 The Institute for the Study of Affective Neuroscience (ISAN) ;70. Intra-Striatal Injection of Streptococcus-Induced Antibodies Leads to Neuropsychiatric and Motor AbnormalitiesLotan D. 1 , Cunningham M. 2 and Joel D. 11 School of Psychological Sciences and Sagol School of Neuroscience, Tel-Aviv University, Israel; 2 Department of Microbiology and Immunology, University of Oklahoma, USA;71. Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patientsRobicsek O. 1 , Karry R. 1 , Petit I. 2 , Salman-Kesner N. 2 , Muller F. 3 , Klein E. 1 , Aberdam D. 2 and Ben-Shachar D. 11 Laboratory of Psychobiology, Department of Psychiatry, Rambam Technion; 2 insertECH, B. Rappaport Faculty of MedicineTechnion; 3 Zentrum f?r Integrative Psychiatrie, Kiel, Germany;72. The adaptive arm of ER stress - a therapeutic target in traumatic brain injuryRubovitch V. 1 and Pick C.G. 1Dept. of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel-Aviv University Israel;73. The Effect of Lithium on phosphoinositide hydrolysis in mice brainSade Y. 1,2 , Bersudsky Y. 2 , Belmaker H.R. 2 and Agam G. 1,21 Department of Clinical Biochemistry and Pharmacology Ben-Gurion University; 2 2Psychiatry Research Unit Mental Health Center, Beersheva, Israel ;74. War- The next generationShachar-Dadon A. 1 , Gini M. 2 , Weintraub Z. 3 , Maayan-Metzger A. 4 and Leshem M. 11 1Department of Psychology, University of Haifa; 2 Center for Children with Communication and Developmental Disorders, Haifa ; 3 3Neonatal Department, Western Galilee Medical Center; 4 4Neonatal Department, Sheba Medical Center ;75. Modulation of motivation measures using deep transcranial magnetic stimulation: An fMRI and behavioral studyShahar H. 1 , Isserles M. 2 , Pell G.S. 1,3 and Zangen A. 11 Department of Life Sciences, Ben-Gurion University of the Negev, Beer sheva, Israel; 2 Department of Psychiatry, Hadassah-Ein Kerem, Jerusalem, Israel ; 3 Brainsway, Jerusalem, Israel;76. Pharmacologic inhibition of the NRG-ErbB4 signaling pathway; effect on reversal learning in adult miceShamir A. and Golani I.1 The Neuroscience Research Laboratory, Mazra Mental Health Center, Akko, Israel; 2 Department of Biothechnolog, ORT Braude College;13


77. The effects of cannabinoids, emotional trauma and trauma reminders on hippocampal fear retrieval, extinction and plasticityShoshan N. 1 , Abush H. 1 , Segev A. 1 and Akirav I. 1 Haifa University;78. Enriched environment effects on juvenile stress-induced alterations of CCL2 and CCR2 expression following induced peritonitis in ratsShtoots L. 1,2,3 , Hugeri O. 1,2,4 , Anunu R. 1,2 and Richter-Levin G. 1,2,3,41 The Institute for the Study of Affective Neuroscience (ISAN), University of Haifa, Haifa, Israel; 2 The Brain and Behavior research Center, University of Haifa, Haifa, Israel; 3 Department ofNeurobiology and Etiology, University of Haifa, Haifa, Israel ; 4 Department of Psychology, University of Haifa, Haifa, Israel ;79. Targeting neurogenesis in the ventral hippocampus with lentiviral Wnt3a gene transfer improves behavioral sympto ms in an Alzheimer''s disease modelShruster A. 1 and Offen D. 1Laboratory of Neuroscience, FMRC, Sackler Faculty of Medicine, Tel-Aviv University;80. The effect of chronic methylphenidate treatment on behavioral parameters and BDNF levels in a rat brainSimchon Y. 1 , Weizman A. 3 and Rehavi M. 1, 21 Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University; 2 The Dr. Miriam and Sheldon G. Adelson Chair and Center for the Biology of AddictiveDiseases; 3 Research Unit, Geha Mental Health Center, Petah-Tikva;81. Effect of the antidepressants sertraline and venlafaxine on survival and tumor growth in males and females breast cancer (4T1 ) xnografted mice modelTarasenko I. 1 , Taler M. 1 , Gershoni A. 1 , Weizman A. 1 and Gil-Ad I. 1Lab. Biological psychiatry, Felsenstein Medical Research Center, Campus Rabin Petah-Tikva 46420;82. Treatment with herbal mixture or SSRI''s on pregnant females predicts efficient behavior of the offspringsVaknin H. 1 , Solomon T. 2 , Rechavi M. 3 and Doron R. 1,21 Dept. of Education and Psychology, The Open University; 2 Dept. of psychology, Tel-Aviv-Yafo Academic College; 3 Dept. of Physiology and Pharmacology, Sackler Faculty of medicine, Tel-Aviv University;83. Hyperammonemia. Bimodal effects of specific ligands for the 18 kDa translocator protein (TSPO) on cell death processes induced by ammoniumchloride. Potential implications for neuropathologyVeenman L. 1 , Caballero B. 1 , Bode J. 2 , Leschiner S. 1 and Gavish M. 11 Technion-Israel Institute of Technology, Faculty of Medicine, Haifa, Israel; 2 Department of Pediatrics, Haematology and Oncology, University Medical Center, Goettingen, Germany84. Cannabinoids prevent the effects of exposure to emotional trauma on extinction and plasticity in a rat model of PTSDWeinshtok-Korem N. 1 and Akirav I. 1 University of Haifa;85. Herbal treatment for anxiety like behavior in ICR miceVersano Z. 1 , Rehavi M. 1 and Doron R. 2,31 Dept. of pharmacology, sacler medical school, Tel-Aviv University; 2 Dep. Of Behavioral Science, the Academic col. Tel-Aviv Yaffo; 3 Dept. of Education and Psychology, The Open University;86. Prereproductive stress in female rats affects CRF type 1 receptor expression in brain and oocytes, and alters behavior in offspringZaidan H. 1 , Golumbic Y. 1 , Leshem M. 1 and Gaisler-Salomon I. 1Department of Psychology, University of Haifa, Israel;87. Deep repetitive Transcranial Magnetic Stimulation (rTMS) of the prefrontal cortex and the insula reduced nicotine addictionDinur-Klein L. 1 , Dannon P. 1 , Kotler M. 1 and Zangen A. 21 Beer Ya''acov Mental Health Center, Beer Ya''acov, Israel; 2 Department of Life Science, Ben-Gurion University, Beer-Sheva, Israel;88. Genetic variants contribute to individual differences in dopamine asymmetry in Parkinson diseaseZozulinsky P. 1 , Kaplan N. 2 , Greenbaum L. 2 , Cohen O. 2 , Yahalom G. 2 , Hassin-Baer S. 2 and Tomer R. 11 Department of psychology, Haifa university; 2 Sagol Neuroscience Center, Chaim Sheba Medical Center, Tel-Hashomer;89. Alpha SMR and SHAM neurofeedback protocols, differential implications on cognitive performance. a double blind studyNir Getter, Rogel Einat, Guez Jonathan, Shirley Abitbul-Gordon, Nachshon Meiran and Doron ToderFaculty of Health Sciences, Ben Gurion University;14


15:30-<strong>16</strong>:30Keynote Speaker:Prof. Doron LancetDepartment of Molecular Genetics, Head of Crown Human Genome Center, Weizmann Institute of Science Rehovotאולם אורןWhole-genome approaches for study brain related diseasesIntroduced by: Prof. Avi Weizmanאולם ??? 11 SymposiumPsychoneuroimmunology: implications ofneuro-immune interactions to psychiatric,malignant and autoimmune diseases.Chairs: Alan Apter and Raz YirmiyaImmune modulation of brain and behaviorfunctioning: From adaptive neuroplasticity toneuro - and psycho-pathologyYirmiya R. Department of PsychologyThe Hebrew University of JerusalemSurgery and stress as risk factors for metastatictumor progression: Mediating mechanisms andprophylactic measures in the clinical settingBen-Eliyahu S. Neuroimmunology Research UnitThe Sagol School of Neuroscience, The School ofPsychological Sciences, Tel Aviv UniversityPANDAS - Can We Reach a Final Verdict: TheEMTICS StudyBenaroya-Milshtein N. Tourette’s Unit, MedicalPsychology Department, SCMCI<strong>16</strong>:30-18:00אולם Symposium 10OCD: preclinical insights andclinical implication15אורן Symposium 9Are there real novelpharmacological targets formood stabilizers?יסמיןגולן ‏)ליד חדר הא וכל(‏Chairs: Joseph Zoar and Hagai HermeshReverse Ethology: Over-Additions and notjust Over-Repetitions in OCD patientsAmitai M. Geha Mental Health Center andSackler Faculty of Medicine, Tel AvivUniversityLow frequency bands dysfunction in OCD -awareness of erroneous content: an ERPstudyCarmi L. Chaim Sheba Medical CenterOCD - From diagnosis to treatment with aDSM-5 perspectiveZohar J. Chaim Sheba Medical CenterChairs: Galila Agam and Revital AmiazNew trends in the treatment of bipolardisorderAmiaz R. Chaim Sheba Medical CenterIdentifying pharmacological targets fornovel mood stabilizers using animalmodelsEinat H. Tel Aviv-Yaffo Academic CollegeIdentifying pharmacological targets fornovel mood stabilizers on the basis of themechanism of action of existing drugsAgam G. Ben Gurion University, Beer Sheva


18:00-18:30 הפסקת קפה ותצוגת חברותאולם אורן18:30-20:00 -תעודות הוקרה ליו"ר ולחברי ועד פורשים,‏ בחירות ליו"ר ולחברי ועד האיגוד החדשיםפרסים:‏פרס ראשון מוענק על ידי פרופ'‏ יוסי זהר,‏תחרות עבודת מדעי יסוד:‏ בחסות ECNPפרס שני ושלישי מוענק על ידי פרופ'‏ דורון גוטהלף,‏ בחסות חברת דקסל פארמהפרס האיגוד למנטור מצטיין ‏)מדע בסיסי(‏ מוענק על ידי פרופ'‏ אריה שלוKeynote Speaker: Prof. James LeckmanNeison Harris Professor of Child and Adolescent Psychiatry, The Child Study and the Departments of Psychiatry,Pediatrics and Psychology, Yale University, New Haven, CT, USAViewed from an Epigenetic Perspective: Who are We?Introduced by: Dr. Yoav KohnSponsored by JANSSEN20:00 ארוחת ערב21:30 אולם אורן - קרולינה בהופעהאחרי ההופעה נפגשים בפאב<strong>16</strong>


Symposium 14Neurostimulation for MajorDepression: Present and Futureיום חמישי,‏ 71 במרץ8:30-10:00Symposium 13New directions in research and treatmentof PTSD173:11-0:71 ארוחת בוקראורן Symposium 12 1Neurobiological and ClinicalAspects of Developmentאולםאולם אורן 2אולם יסמיןChair: Hilik LevkovitzNeuroplastic and Behavioral effects ofDeep Electromagnetic Stimulation inDepression: From Animal Models toHuman ApplicationZangen A. Ben Gurion University, BeerShevaIs There a future to Brain Stimulation inChild and Adolescent DepressionBloch Y. Shalvata Mental Health Centerand Sackler School of Medicine, Tel AvivUniversityResults from the internationalmulticentre double-blind randomizedcontrolled trial on the efficacy andsafety of Deep Transcranial MagneticStimulation (DeepTMS) for MajorDepressionLevkovitz Y. Shalvata Mental HealthCenter and Sackler School of Medicine,Tel Aviv UniversityChairs: Ehud Klein and Gal Richter-Levin(Supported by the Institute for the Studyof Affective Neuroscience, Haifa)A View of PTSD from a Sleep Biology PerspectiveNeylan T. Department of Psychiatry UCSF and Directorof PTSD Research; Deputy Associate Chief of Staff forResearch at VAMCEffects of oxytocin on empathy and on emotionalregulation in PTSD patientsPalgi S. Department of Psychiatry, Rambam Health CareCampus, Faculty of Medicine Technion.Association among clinical response and hippocampalvolume in individuals with posttraumatic stressdisorder (PTSD) receiving cognitive behavioral therapy(CBT)Levy-Gigi E. Institute for the study of AffectiveNeuroscience, University of Haifa.Neural traces of stress: cortisol related sustainedenhancement of amygdala-hippocampal functional couplingVaisvaser S. Functional Brain Center, Wohl Institute forAdvanced Imaging, Sourasky Medical CenterSecondary prevention in PTSD - state of the artZohar J. ECNP President, Department of Psychiatry,Chaim Sheba Medical CenterChairs: Aron Weller and Gil ZalsmanStimulants Improve Theory of Mind inChildren with Attention Deficit /Hyperactivity DisorderBloch Y. Shalvata Mental Health CareCenter and Sackler Faculty of Medicine,Tel-Aviv UniversityEnvironmental manipulations duringperi-adolescence in Wistar Kyoto ratsShbiro L. Bar-Ilan UniversityThe effects of post-natal administrationof the selective serotonin reuptakeinhibitor flouxetine on female and maleratsYankelevitch-Yahav R. Tel Aviv UniversityDisruptive Mood Dysregulation Disorder(DMDD) a new concept in childpsychiatry and DSM 5Zalsman G. Geha Mental Health Center andSackler Faculty of Medicine Tel AvivUniversity


אולם אורן 10:00-10:45E-Poster presentations for the best-poster competition IIChairs: Amir Krivoy, Ravid Doron and Avi Avital10:45-11:00 הפסקת קפה ותצוגת חברותעד 00:11 פינוי החדרים11:00-11:45Special Symposium: New Horizon, oral presentationsאולם אורןChair: Amir KrivoyThe Effect of Alcohol Seeking Behavior Following a Novel Herbal Treatment for AnxietyMotsan S. Tel-Aviv-Yafo Academic CollegeCognitive and Emotional Assessments, Reloaded - A novel prism created by computer games and gamersSegev A. Shalvata Mental Health Center; 2 Sackler Faculty of Medicine, Tel Aviv UniversityCurcumin as an add-on to antidepressive treatment: A randomized, double-blind, placebo-controlled, pilot clinical studyBergman J. Mental Health Center Tirat Carmel, Bruce Rappaport Faculty of Medicine Technion- Haifa, IsraelHyperammonemia. Bimodal effects of specific ligands for the 18 kDa translocator protein (TSPO) on cell death processes induced byammonium chloride. Potential implications for neuropathologyVeenman L. Technion-Israel Institute of Technology, Faculty of Medicine, Haifa, IsraelPTSD and Mild Traumatic Brain Injuries in Children - Preliminary ResultsShorer M. Schneiders Childrens Medical Center of IsraelStress induced alteration in the expression of genes depend on the “transcriptional phenotype” in ratsFinkelstein O. Lab of Psychobiology, Dept of Psychiatry, B.Rappaport Faculty of Medicine, Technion, ITT and Rambam18


אולם אורן 11:45-13:00פרסים לפוסטרים מצטיינים:‏Sponsored by NIPIמוענקים ע"י ועדות השיפוט:‏ יום ג':‏ יו"ר - רונן סגמן.‏ חברים:‏ רננה איתן,‏ אתי גראואר,‏ גיל זלצמן,‏ אירית עקירב,‏ גל ריכטר לויןיום ד':‏ יו"ר - רונן סגמן.‏ חברים:‏ עומר בונה,‏ גל ידיד,‏ דורית בן שחר,‏ רז ירמיהKeynote Speaker: Dr. Ofer YizharDepartment of Neurobiology, Weizmann Institute of Science RehovotOptogenetic interrogation of cortical circuitsIntroduced by: Prof. Arie Shalev13:00-14:00 ארוחת צהרים קלה,‏ מילוי משובים וסיום הכנס19

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