Inpatient Hyperglycemia

Basal Bolus Insulin Regimen‣ D/C oral antidiabetic drugs on admission‣ Starting total daily dose (TDD): 0.5 U/kg/day‣ TDD reduced to 0.3 U/kg/day in patients ≥ 70 years ofage or with a serum creatinine ≥ 2.0 mg/dL‣ Half of TDD as insulin glargine and half as insulinglulisine*– Glargine - once daily, at the same time of the day– Glulisine- three equally divided doses (AC)The goal of insulin therapy was to maintain fasting and pre-meal glucose concentrationbetween 100 mg/dl and 140 mg/dl.*If a patient was not able to eat, insulin glargine was given but, insulin glulisine was held untilmeals were resumed.