BenchTop Pro with Omnitronics 9 Liter - Bartelt

Benchtop Pro with OmnitronicsThe VirTis BenchTop Pro freeze dryers havebeen designed to meet the needs of the mostdemanding research laboratories. Eachsystem can be configured to accommodatepresent and future requirements. Condenserrefrigeration packages of -55°C, -75°C,-85°C and -105°C can meet the demandsof both aqueous or aqueous-solvent basedformulations.You can configure your systemto run just a few samples orto process a relatively heavyload with condenser sizechoices of 3 liter, 8 liter or9 liter. Selecting a size andtemperature configurationallows you to maximize the useof the freeze dryer in your labwhile not paying needlesslyfor unnecessary capacity orrefrigeration.Each system can beconfigured to meetthe needs of the mostdemanding researchlaboratories.02

ManifoldsManifolds are available in a varietyof styles and are designed to beinterchangeable. There are a number ofconsiderations when selecting a manifold.In a multi-user lab it is often best to utilizea robust stainless steel manifold. Inapplications where inorganic solvents arebeing utilized or you are rack drying andwant to ensure visibility an acrylic manifoldwould be preferred. In applicationswith organic solvents the stainless steelmanifolds will provide long lasting use.03

Omnitronics ControllerThe Omnitronics Controller simplifies freeze dryingand makes the system easy to operate. One touchstart up and shut down ensure that your productand freeze dryer are protected from inappropriateprocedures. The graphic display provides at-aglanceunderstanding of the status of the freezedryer and whether or not appropriate freeze dryingconditions exist. Audible alarms help notify theuser of potential problems with the system andhence, with the product. All Omnitronics controllerscome complete with a trending screen that allowsyou to watch critical parameters on an on-goingbasis if required. Utilizing the optional Ethernetcontrol, you can connect the freeze dryer to yourcompany’s or institution’s network, and monitorand/or control your freeze dryer from any otherlocation on the network. The Ethernet optionalso allows print out in a batch record, alphanumeric,type report.One touch start up and shutdown ensure that your productand freeze dryer are protectedfrom inappropriate procedures.04

Don’t waste time withslow & messy defrostingThe hot gas defrost in the BenchTop Proallows for fast turnaround time and helpsminimize clean up efforts when havingto pour warm water into a condenser. Inaddition, corrosive solvents which are moreactive at ambient and higher temperatureswill spend a minimum amount of dwell timein the condenser with fast hot gas defrost—no need to wait overnight to drain thesystem.05

VirTis/SP Scientific supports your freeze drying endeavors with a team of technicallyqualified associates who can help you choose the right system and provide you withhelpful application tips. In addition, SP Scientific provides the globally recognizedLyoLearn Webinar series. These are free webinars, provided by industry experts on topicsof interest to the freeze drying community. Our technical papers and application notescan be downloaded from our website at your convenience and are designed to help youget the most out of your freeze dryer.Standard Omnitronics• High performance PLC controller• Easy to use interface provided by full colortouch screen navigation.• Ensure a longer lifetime for your freeze dryerby avoiding utility degradation conditionssuch as high ambient and low voltage withalert notifications• Real time graphical screen data logging toreview system parameters during a run• Help protect your product from unfavorableconditions with “out of range” and “inrange” for freeze drying indicators• Save time with one button start-up and onebutton shut-down• Stores years of data on micro memory card• Set point control with automatic PID tuning• Precise alpha-numeric display of setting andread-out temperatures• Currently available in English, Spanish,German & French. Other languages may beavailable on request.• User selectable pressure in millibars, millitoror pascals. Temperature in °C or °FOmnitronics withEthernet Option• Control and/or monitor your system fromanywhere on your network• Enable the freeze dryer to email you ifthere is a process alert/alarm• Full reporting capabilities with batchreports that can be exported to WindowsExcel®• Optional remote service support byallowing our qualified technicians toaccess your system06

Features of the BenchTop Pro• Condensers of 3, 8 and 9 liters in a bench topfootprint• Refrigeration packages for maximum lowtemperature of -55°, -75°, -85° or -105°C• One touch start-up and shut-down• Pressure control to avoid back-streaming or forfaster freeze drying• A variety of manifolds to accommodate mostprocessing configurations• Rugged and reliable Pirani vacuum sensor• Hot gas defrost in approximately 10 minutes orless• Optional vacuum pump isolation valveSelection GuideThere are two main criteria for selecting the benchtop freeze dryer that is right foryou. The first is determining what condenser capacity you need in between defrostcycles. The second is to determine what solvents you may be using in your process.When utilizing water as the only solvent the highest condenser temperature offered isappropriate. In cases where organic or inorganic solvents are being utilized as partof the solvent matrix the lowest temperature condenser is always preferred.Load CapacitySolvents 3 Liter 8 Liter 9 LiterWater ES (-55°C) XL (-75°C) ES (-55°C)Water and inorganic solvents XL (-75°C) ZL (-105°C) EL (-85°C)Water & organic solvents XL (-75°C) ZL (-105°C) EL (-85°C)Manifold Material ChoiceAcrylic or stainless steel. Multiple user labs mayhave better experience with stainless steel.Maximize use of acrylic and minimize use ofstainless steel.Maximize use of stainless steel and minimizeuse of acrylic if possible.Vacuum PumpConsiderationsStandard oil sealed, rotary vane directdrive pump. When working in lowpressure conditions consider a dry scrollpump if oil backstreaming is a concern.Standard pump with corrosion resistantoil or combination standard pump withdiaphragm pump.Standard pump with corrosion resistantoil or combination standard pump withdiaphragm pump.Water & both organic and inorganicsolventsXL (-75°C) ZL (-105°C) EL (-85°C)Maximize use of acrylic if higher in organicsolvents. Maximize use of stainless steel ifhigher in organic solvents.Combination standard pump withdiagphragm pump.07

BenchTop Pro withOmnitronics3L Freeze DryerThe BenchTop Pro with Omnitronics3 Liter system is designed asa personal freeze dryer or forsmall laboratories processing lessproduct at any one time. This unitis available with all of the manifoldchoices that can be used on thelarger benchtop system giving it thesame flexibility and performance.• Condenser temperature option of-55°C (-52°C for 50Hz) or -75°C(-72°C for 50Hz)• CFC free refrigerants• Overall condenser capacity of 3liters• Approximate 24 hour rating of 2liters/24 hour (extreme pressureand temperature, water only)*• Omnitronics Control for monitoringcritical freeze drying parametersand for vacuum control• Remote control, batch reportingand emailed alarms with Ethernetinterface• Fast turnaround time with hot gasdefrost and smooth condenser walls• Alarms for out-of-range conditions*The 24 hour rating is not reproduciblein the lab with product. This rating is toillustrate the efficiency of the refrigerationdesign from one system to another. It isbased on loading as much water onto thefreeze dryer in 24 hours as possible withequipment not typically used in freezedrying applications08BenchTop Pro with Omnitronics 3 Liter Freeze DryerCondenser blank off (no load)temperatureCondenser capacity in 24 hours(water, heaviest load)Overall condenser capacityOmnitronics control* Vacuum indication in millitor,microbar or pascals (user selectable)ES -55°C (-52°C for 50Hz) / XL -75°C(-72°C for 50Hz)Approximately 2 Liters3 LitersAtmospheric to 1 mT with highestaccuracy between 1 and 1000 mT* Vacuum regulation Pressure control set point with vacuumbleed valve +/- 20 mT* Temperature indication in °C or °F "T" type thermocouples(user selectable)* Voltage and ambient temperatureindicatorsAlarms if out of acceptable range forsystem* Communication ports Ethernet connectionDefrost MethodHot gasSystem refrigerantCFC freeCondenser typeSmooth wall interior with refrigerationcoils on exterior of condenserCompressor(s)Single 1/3 HPAverage time for pull down to 100 mT 15 minutesUltimate system vacuum with manifold 20 mTBase cabinet dimensions W x D x HWeight(unpackaged and without manifold)Standard VoltagesManifold and Vacuum Pumps Sold Separately- See Accessories

BenchTop Pro withOmnitronics8L Freeze DryerThe BenchTop Pro with Omnitronics8 liter is designed for heavier loadsand for use with solvents other thanwater. It is available with a -75°Cor -105°C condenser. The -105°Coption is preferred for applicationsinvolving low freezing point solventssuch as TFA, acetronitrile andalcohols. Even if the freezing pointof your solvent is below -105°C thistemperature condenser is more likelyto liquefy the solvent and thus preventit from migrating easily to the vacuumpump.• Offered in low and ultra-low condenserconfiguration -75°C (-72°C for 50Hz)or -105°C (-102°C for 50Hz)• CFC free refrigerants• Condenser capacity total of 8 liters• Approximate 24 hour rating of 3liters/24 hours (extreme pressure andtemperature, water only)*• Omnitronics Control for monitoringcritical freeze drying parameters andfor vacuum control• Remote control, batch reporting andemailed alarms with Ethernet interface• Fast turn around with hot gas defrost.• Alarms for out-of range-conditions*The 24 hour rating is not reproducible in thelab with product. This rating is to illustratethe efficiency of the refrigeration designfrom one system to another. It is based onloading as much water onto the freeze dryerin 24 hours as possible with equipment nottypically used in freeze drying applicationsBenchTop Pro with Omnitronics 8 Liter Freeze DryerCondenser blank off (no load)temperatureCondenser capacity in 24 hours(water, heaviest load)Overall condenser capacityOmnitronics control* Vacuum indication in millitor, microbaror pascals (user selectable)XL -75°C (-72°C for 50Hz) /ZL-105°C (-102°C for 50Hz)Approximately 3 Liters8 LitersAtmospheric to 1 mT with highestaccuracy between 1 and 1000 mT* Vacuum regulation Pressure control set point with vacuumbleed valve +/- 20 mT* Temperature indication in °C or °F "T" type thermocouples(user selectable)* Voltage and ambient temperatureindicatorsAlarms if out of acceptable range forsystem* Communication ports Ethernet connectionDefrost MethodHot gasSystem refrigerantCFC freeCondenser typeSmooth wall interior with refrigerationcoils on exterior of condenserCompressor(s) XL is one 1/2 HP and ZL is two 1/2HPAverage time for pull down to 100 mT 15 minutesUltimate system vacuum with manifold 20 mTBase cabinet dimensions W x D x HWeight(unpackaged and without manifold)Standard VoltagesManifold and Vacuum Pumps Sold Separately- See Accessories09

BenchTop Pro withOmnitronics9 LiterThe BenchTop Pro with Omnitronics9 liter is the high capacityworkhorse of the bench top freezedryer product family. Built for labsthat require greater throughput andfreeze drying availability, for somelabs it will handle their weeklyrequirements without shut downand defrost. It is available with a-55°C or -85°C condenser• Offered in low and ultra-lowcondenser configuration -55°C(-52°C for 50Hz) or -85°C (-85°Cfor 50Hz)• CFC free refrigerants• Condenser capacity total of 9 liters• Approximate 24 hour rating of 5liters/24 hours (extreme pressureand temperature, water only)*• Omnitronics Control for monitoringcritical freeze drying parametersand for vacuum control• Remote control, batch reportingand emailed alarms with Ethernetinterface• Fast turn around with hot gasdefrost.• Alarms for out-of range-conditions*The 24 hour rating is not reproduciblein the lab with product. This rating is toillustrate the efficiency of the refrigerationdesign from one system to another. It isbased on loading as much water onto thefreeze dryer in 24 hours as possible withequipment not typically used in freezedrying applications10BenchTop Pro with Omnitronics 9 Liter Freeze DryerCondenser blank off (no load)temperatureCondenser capacity in 24 hours (water,heaviest load)Overall condenser capacityOmnitronics control* Vacuum indication in millitor, microbaror pascals (user selectable)ES -55°C (-52°C for 50Hz) /EL -85°C(-82°C for 50Hz)Approximately 5 Liters9 LitersAtmospheric to 1 mT with highestaccuracy between 1 and 1000 mT* Vacuum regulation Pressure control set point with vacuumbleed valve +/- 20 mT* Temperature indication in °C or °F "T" type thermocouples(user selectable)* Voltage and ambient temperatureindicatorsAlarms if out of acceptable range forsystem* Communication ports Ethernet connectionDefrost MethodHot gasSystem refrigerantCFC freeCondenser typeSmooth wall interior with additionalinterior refrigeration coilsCompressor(s) ES is one 1/2 HP and EL is two 1/2HPAverage time for pull down to 100 mT 15 minutesUltimate system vacuum with manifold 20 mTBase cabinet dimensions W x D x HWeight(unpackaged and without manifold)Standard VoltagesManifold and Vacuum Pumps Sold Separately- See Accessories

Accessories for the BenchTop ProTree or “T” type ManifoldsAvailable in 8 or 12 port configuration. 304 Stainless steel complete with QuikSeal Valves and built in adaptor plate.Part Number Description DimensionsBTP-MST-08 Stainless steel manifold, 8portsBTP-MST-12 Stainless steel manifold, 12portsHEIGHT 19.25” (48.9 CM),LENGTH 15” (38.1 CM), WIDTH15.25” (38.74 CM)HEIGHT 19.25” (48.9 CM),LENGTH 15” (38.1 CM), WIDTH23” (58.42 CM)Condensate Drip Pan Kit for Tree of “T” Type ManifoldsThis condensate drip pan kit will provide support for flasks on the Tree manifoldand also collect condensate as it drips off the outside of the product containersduring freeze drying.Part NumberCPKDescriptionStainless steel flask support with plastic traysCondensate Drip Pan Kit for Tree of “T” Type ManifoldsThis condensate drip pan kit will provide support for flasks on the Treemanifold and also collect condensate as it drips off the outside of the productcontainers during freeze drying.Part NumberCPKDescriptionStainless steel flask supportwith plastic traysVertical ManifoldAvailable in 12 port configuration. 316 stainless steel complete with Quick SealValves and built in adaptor plate.Part Number Description DimensionsBTP-MSV-12 Stainless steel manifold, 12portsHEIGHT 16.25” (41.28 CM),LENGTH 15” (38.1 CM), WIDTH15” (38.1 CM)Part NumberCPKDescriptionStainless steel flask support with plastic trays11

Drum ManifoldsClassic drum type manifolds are available in both stainless steel and acrylicconfiguration. Comes complete with condenser adaptor plate of same material.Accessory racks can be coupled with these manifolds for rack drying—either heated orunheated.Part Number Description DimensionsBTP-DA-08-0 8 port acrylic drum manifold DRUM - HEIGHT 12.25” (31.12 CM) ID 14.25”(36.2 CM) OD, WIDTH Ø9” (22.86 CM) ID,Ø9.5” (24.13 CM) ODADAPTER PLATE – HEIGHT 1” (2.54 CM),WIDTH Ø15” (38.1 CM)OVERALL ASSEMBLY – HEIGHT 15” (38.1 CM),WIDTH Ø18” (45.72 CM) WITH QUICK SEALVALVES INSTALLEDBTP-DA-12-0 12 port acrylic drum manifold DRUM – HEIGHT 16.25” (41.28 CM) ID, 18”(45.72 CM) OD, WIDTH Ø11.5” (29.21 CM)ID, Ø 12” (30.48 CM) ODADAPTER PLATE – HEIGHT 1” (2.54 CM),WIDTH Ø15” (38.1 CM),OVERALL ASSEMBLY – HEIGHT 18.75”, WIDTHØ20.5” (52.07 CM) WITH QUICK SEAL VALVESINSTALLEDBTP-DA-12-HBTP-DS-18-012 port acrylic drum manifoldfor use with heated racks18 port stainless steel drummanifoldDRUM - HEIGHT 16.25” (41.28 CM) ID, 18”(45.72 CM) OD, WIDTH Ø11.5” (29.21 CM)ID, Ø12” (30.48 CM) ODADAPTER PLATE - HEIGHT 1.5” (3.81 CM),WIDTH Ø15” (38.1 CM)OVERALL ASSEMBLY – HEIGHT 19.25”, WIDTHØ20.5” (52.07) WITH QUICK SEAL VALVESINSTALLEDDRUM - HEIGHT 13” (33.02 CM) ID, 13.25”(33.66 CM) OD, WIDTH Ø12” (30.48 CM) ID,Ø13” (33.02 CM) ODSST ADAPTER PLATE – HEIGHT 0.25” (0.64CM), WIDTH Ø15” (38.1 CM)ACRYLIC COVER – HEIGHT 0.75” (1.91 CM),WIDTH Ø13.5” (34.29)OVERALL ASSEMBLY – HEIGHT 14.25” (36.2CM), WIDTH Ø21” (Ø53.34 CM) WITH QUICKSEAL VALVES INSTALLEDDrum Manifold RacksRacks are constructed of 304 stainless steel and adjustable.Part Number Description DimensionsBR-3U-08 3 tiered rack for BTP-DA-08 HEIGHT 10.5” (26.67 CM), WIDTH Ø8.5(21.59 CM), SPACING 3.50” (8.89 CM)BR-3U-12 3 tiered rack for BTP-DA-12 HEIGHT 14.5” (36.83 CM), WIDTH Ø10.5(26.67 CM), SPACING 4.75” (12.07 CM)BR-3U-18 3 tiered rack for BTP-DA-18 HEIGHT 12” (30.48 CM), WIDTH Ø10.5(26.67 CM), SPACING 3.75” (9.53 CM)BR-3H-133 tiered rack for BTP-DA-12 withon off heaterHEIGHT 12” (30.48 CM), WIDTH Ø8.5 (21.59CM), SPACING 4.75” (12.07 CM)12

Wide Mouth Filter Seal FlasksThese borosilicate flasks are specially designed for manifold freeze drying. The flatbottom makes it easy to stabilize the flask in its upright position for “plug” or staticfreezing. The wide mouth of the flask makes it easier to place product in the flask andperhaps even more importantly, remove product from the flask. The snap on silicone topensures a good vacuum seal and comes complete with a filter to eliminate the possibilityof cross contamination when several flasks are on the same dryer. All components canbe autoclaved. The flask itself is available in regular and in safety coated configurations.Must be used with manifold adaptors.Regular FlaskPart NumberSafety CoatedPart NumberMaximumCapacityMaximumFill235390 312892 40 ml 20 ml235382 312900 75 ml 35 ml118174 312918 150 ml 75 ml118208 312918 300 ml 150 ml118232 312934 600 ml 300 ml118273 312942 1200 ml 600 ml118307 312959 2000 ml 1000 mlManifold AdaptorsPart Number Material Shape Port Size CompatibleFlasks367424 Plastic Straight Barb ¾” 150 – 2000 ml179655 Glass Straight ¾” 150 – 2000 ml177923 Stainless steel Straight ¾” 150 – 2000 ml177899 Glass 45 degree ¾” 150 – 2000 ml177931 Stainless steel 45 degree ¾” 150 – 2000 ml179622 Glass Straight ¾” 40 & 75 ml177873 Glass 45 degree ¾” 40 & 75 mlDon’t see the adaptor you need? Please inquire.13

Ampule AdaptorDesigned to hold 19 ampule type containers on a single valvePart NumberDescription413534 19 port ampule adaptorWe also carry a full line of sealing torches and ampules. Please inquire.Container SystemTwo container systems are offered. One for bulk and one for stopperingapplications. Containers are made of 304 SS and are attached to yourmanifold with vacuum tubing for processing in bulk or in vials.Part Number Description Dimensions438032 Bulk ss containerSC-1 Small stoppering container 7 – 5 ml vials, 5 – 10 ml vials,4 – 30 ml vials, 1 – 100 ml vialVacuum PumpsVirTis/SP Scientific is pleased to offer a full line of vacuum pumps to solveany application need. Included in our offering are the standard two stage,oil sealed rotary direct drive vacuum pumps as well as dry scroll typepumps and combination pumps that are joining of the standard pump witha diaphragm pump for service in highly corrosive environments.14VacuumForeline TrapsThese traps are designed tohelp prevent the migration ofcontaminants to the vacuumpump or to minimize vacuumpump oil back-streaming.They are placed in thevacuum line between thefreeze dryer and the vacuumpump.Part NumberFTAFTA-SSFTA-ACFTA-MSDescriptionFilter trap housing, insertpurchased separatelySoda sorb insert for acid applicationsActivated charcoal insert for organic solvent applicationsMolecular sieve insert for water vapor and to helpminimize oil backstreaming

SP Scientific Supports You in Ways Unrivaled in the Industry:LyoLearn Webinars:Free online seminar series featuring topics of interest to lyophilization scientists andpresented by industry experts. Live sessions allow participants to interact with renownedfreeze-drying specialists, such as Dr. John Carpenter, Dr. Steve Nail, Dr. Michael Pikal,and other who’s who of the freeze drying community. Each online LyoLearn Session isrecorded and archived for future viewing.Hands-On Training:SP Scientific’s hands-on training courses offer attendees the chance to optimize theirlearning experiences by using tangible applications in a controlled setting. Led by “go-to”leaders in the lyophilization industry, these courses are a must for anyone getting startedin freeze drying or scientists looking for collaborative environment to share best practices,ideas and theories.Technical Briefs:SP Scientific’s technical briefs are relevant papers covering in-demand topics. Availablein a variety of languages, titles include: The Relevance of Product Resistance in PrimaryDrying, The Importance of Controlling Nucleation Temperature During the Freeze Step,Case Studies in Diagnosing and Correcting Problematic Lyophilization Cycles and/orFormulations, Basic Principles of Freeze Drying, and Basic Lyophilizer Maintenance Helpsto Assure Good Results.All of this is available on our websitewww.SPScientific.com.Logon to learn more!03