SK Gupta* et al. /International Journal Of Pharmacy&Technology

S.K.Gupta* et al. /International Journal Of Pharmacy&TechnologySeven days pretreatment with drugs increase the mucosa secretion also. So, OSL extract has antiulcerogenicproperty against experimental ulcers 31 .Chamomile (Matricaria recutita): Chamomile has been used in connection with colic, gastritis, indigestion andheartburn, peptic ulcer, ulcerative colitis and wound healing 19 .Active constituents: The flowers of chamomile provide 1-2% volatile oils containing α-bisabolol, α-bisabolol oxidesA and B, and matricin , bioflavonoids apigenin, luteolin and quercetin. These active ingredients contribute tochamomiles anti-inflammatory, antispasmodic and smooth muscle relaxing action, particularly in gastrointestinaltract 32 .Benincasa HispidaExtract : Metahanolic fruit extractModel : Inbred Male wistar rats Swiss albino miceAntiulcer studies: HCl/ ethanol induced gastric lesions indomethacin-HCl/ethanol model Aspirin pylorus ligationmodel.Rabdosia trichocarpa: A diterpane, trichorabdal a from Rabdosia trichocarpa, show a very strong in vitroantibacterial activity against helicobacter pylori. Regard to antibacterial activity of extract and constituents treatmentof gastritis is due to suppression of pylori since the extract of R. trichocarpa particularly inhibit the growth of H.pylori. It is promising native herb treatment for patient with gastric complaints including gastric ulcer caused by H.pylori 33 .Neem: The antiulcer effect of aqueous extract of leaves of neem tree investigate on rats exposed to 2-hr. coldrestraint stress or given ethanol orally for in extracts administer in doses of 10,40 or 160 mg level/kg body weighteither as single or five dose treatment regimens.Means dose-dependently reduced gastric ulcers severity in rats subjected to stress and decreased ethanolproduced gastric mucosal damage. The extract appeared to prevent most cell deregulation and to increase the amountIJPT | March-2011 | Vol. 3 | Issue No.1 | 824-853 Page 842