Henning Hermjakob - ProteomeBinders

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PSI MI components• XML format• Controlled vocabulary• Implemented in databases(DIP, MINT, MIPS, IntAct)• Validation tools• Process for controlledvocabulary and schemamaintenance• Inter-database exchange(in progress)Henning HermjakobProteomics Services TeamProteomeBindersAlpbach meeting, March 2007
Working hypothesis:Binder-Target binding is a special case of molecularinteractionTargetPrESTModificationsExpressionACSeqAntigenBinding *ExperimentTypeSource*Binder inst.SpecificityScoreEvidenceMethodLabBinderconcentrationHenning HermjakobProteomics Services TeamProteomeBindersAlpbach meeting, March 2007
Page 1 and 2: Designing a Binder DatabaseProteome
Page 3 and 4: Initiatives for Proteome Binderdeve
Page 5 and 6: Data fragmentation• Difficult to
Page 7 and 8: HUPO PSI MI XML format• Community
Page 9: PSI MI components• XML format•
Page 13 and 14: Data model development• Mapping r
Page 15 and 16: Next steps• Development of protot
Page 17: Acknowledgements• Sandrine Palcy,

Henning Hermjakob - ProteomeBinders

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