Henning Hermjakob - ProteomeBinders

Recommendations

Info

Current status• “Working hypothesis” confirmed:At least the core data for the ProtemeBinder use casescan be consistently mapped to the PSI MI 2.5 XMLschema• Detailed proposal for the extension of the PSI MIcontrolled vocabularies• To be discussed/approved at PSI meeting April 23-25, 2007, inLyon, France• Some controlled vocabularies specific toProteomeBinders need to be developed• Some schema extensions potentially required in the nextversion of the PSI MI schemaHenning HermjakobProteomics Services TeamProteomeBindersAlpbach meeting, March 2007
Next steps• Development of prototype ProteomeBinders productiondatabase• Capture detailed records on binder production, properties, andquality control• Existing IntAct molecular interaction database can be used asbasis for development• Development of prototype ProtemeBinders warehouse• Present summarised, processed user views, for example qualityassessments based on multiple independent experiments• Advanced tools, for example support for binder array designHenning HermjakobProteomics Services TeamProteomeBindersAlpbach meeting, March 2007
Page 1 and 2: Designing a Binder DatabaseProteome
Page 3 and 4: Initiatives for Proteome Binderdeve
Page 5 and 6: Data fragmentation• Difficult to
Page 7 and 8: HUPO PSI MI XML format• Community
Page 9 and 10: PSI MI components• XML format•
Page 11 and 12: Working hypothesis:Binder-Target bi
Page 13: Data model development• Mapping r
Page 17: Acknowledgements• Sandrine Palcy,

Henning Hermjakob - ProteomeBinders

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?