Chronisch Vermoeidheidssyndroom: diagnose, behandeling en ...

30 Chronic Fatigue Syndrome KCE reports 88
CFS. Among subjects who were nonfatigued and fatigued for less than 6 months, the 1year
incidence of CFS was 180 per 100 000 persons (95% CI, 0-466 per 100 000
persons).
Results from attempts to estimate incidence in the Netherlands (research team from
Nijmegen) indicate that 2 900 to 9 800 new cases could be diagnosed by year, i.e. an
incidence of CFS being 18 per 100 000 persons to 60 per 100 000 persons c . 59
2.4.5 Incidence of CFS in children and adolescents
A longitudinal study is needed to estimate incidence of CFS. Rimes et al. (2007)
conducted such study in a random general population sample of 842 British adolescents
(aged 11 through 15 years). 65 At time 1, the point prevalence was 0.1% for CFS (95% CI:
0.0% – 0.4%). Four to six months later, 4 new cases of CFS occurred for a 0.5%
incidence (95% CI: 0.01% – 0.9%).
2.4.6 Incidence: discussion
Results from attempts to estimate incidence in adult populations indicate that 1 to 37
new cases could be diagnosed by year per 10 000 population. For adolescents, 100 new
cases could be diagnosed by year per 10 000 population. This high incidence is balanced
by high remission rates 4 to 6 months later. 65 Overall, taking this high remission rate
into account, CFS in children and adolescents may not be extremely disabling. The
presence of family psychopathology may be a determining variable, but this deserves
further study.
c In 2004, number of inhabitants equalled 16.3 million (http://www.cbs.nl/nl-
NL/menu/themas/bevolking/publicaties/artikelen/archief/2004/2004-193-pb.htm)