PDF file - David Thomas Contact Lenses

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SafetyComfortec TM : ideally balanced combinationof 4 complementary agentsPreventscorneal stainingGLYCOLIC ACIDNatural vegetal acidLess proteinadhesionGLYCINENon ionicamino acidAMPDAmino alcoholCompatibilitywith soft lensesPROPYLENE GLYCOLNon ionic moisturizerCushioning effecton lens surfaceComfortec TM actionby ionic interaction• with Polyhexanide for better safety andhigher disinfection• with tears lysozyme to prevent proteinadhesionby hydrogen bonding• for more water moleculesto moisturizeSynergicdisinfectionISO 14729 Stand alone testMenicare TM Soft meets the first criteria for disinfecting solutionin 20 minutes.EnhancingMACROGOL HCO- 60surfactant to removelipid depositsLog reductionafter 4 hours654MeniCare SoftSolution ASolution BSolution CSolution DPOLYHEXANIDE disinfectanteffectiveness for a no rub rinseand soak care regimen.3210PseudomosasaeruginosaSerratiamarcescensS. aureus CandidaalbicansTested micro-organisms1st criteria for disinfecting solutionFusariumsolaniSource : Menicon
Compatibility with soft lensesClinical data on Silicone-hydrogelsSubjective comfort, visual acuity and cornealand conjunctival safety signs confirmed thecompatibility of MeniCare TM Soft solutionwith silicone-hydrogel lenses*when comparing patients results using:• one month MeniCare TM Soft(Comfortec TM - Polyhexanide)• versus one month a control solution*20 patients fitted with Acuvue Advance Johnson & Johnson Vision Care21 patients fitted with Focus Night & Day CIBA VisionThe boxes represent the 25 th and 75 th centiles and thewhiskers indicate the 10 th and 90 th centiles (Data outsideare represented by a dot). The median and mean arerepresented by a horizontal line and a diamond respectively,within the box.Source : independant universitary research centreMaximum safety on corneal cellsBy measuring in vitro the concentrationthat suppresses cells growth to 50 % ofcontrol value:The higher IC50* meansmaximum safety on cells growth, lowercytotoxicity.Anti-Acanthamoebaand virus effectivenessIC 50ISO 10993-5 Cells growth and 50% inhibitory concentration (IC 50)Lowercytotoxicity1086420HighercytotoxicityMeniCare SoftSolution DSolution ASolution BSolution CSource : Menicon*50% Inhibitory ConcentrationMeniCare TM Soft solution is an effective stand-alone disinfecting product against pathogenic free-living Acanthamoeba andviral pathogen HSV-1*. It is also able, when used as a no-rub and rinse solution, to remove pathogenic viruses** from softcontact lenses (4-5 log reduction).(Source : Dr Kilvington BCLA 2005)*tested Amoeba and virus : A. polyphaga, A. castellanii, cysts and trophozoites, / Herpes simplex virus type 1 (ISO 14729 stand alone test).**tested viral pathogens : Herpes simplex virus type 1, Polio virus type 2 and Adenovirus type 8 (regimen test).
Page 1: Safety and comfortNot all soft lens

PDF file - David Thomas Contact Lenses

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