CO-NH2 CO-NH2 â€žâ€žCO-NH2 CO-NH2

More documents

Recommendations

Info

11.5 11.6 11.7 11.8 11.9 11.10 11.11 11.12 R COOC2H5 COOC2H5 „ „ „ COOQHg COOC2H5 „ COOC2H5 „ COOC2H5 „ COOC2H5 „ COOC2H5 a CH3 H „ SJ 55 ?) H H „ „ 5 H „ H 55 H „ H H CH3 „ ?> }) 55 H H „ H „ H H „ CH3 NAA' N(CH3)2 N(CH3)2 „ „ NC4H8 (c) NC4H8O (d) „ N(C2H5)2 5? NC4H7-CH3 (a) NC5H10 (b) 5? NQH8O (d) TABLE IV—continued Formula C21H27NO2 C21H27NO2 „ ?? 5 55 C22H27NO2 C22H27NO3 „ „ C22H29NO2 „ C23H29NO2 „ C23H29NO2 ?? C23H29NO3 Base — — — — bo.70 158—68 — oil — bo.5 175-80; m 68-5-70 b4 218-22 m 68-70 b4 218-22 m65-7 bo.4 165 — b5 200-2 b3.5 212-4 b3.3 212-4 b9 235-40 bo.4 170-8; m 69-70-5 b3 208-12 — — — Salts HCl 191-2 /-HCl 169-70 HCl 151-2 /-HCl 172-3 dec. rf-HCl 171-3 dec. dl-HCl 178-5-80 dec. HCl 178-9 HBr 167-8; HCl deliquescent C2H2O4 157-8 HCl 167-5-8-5 HCl 166-7 HCl 168-9 HCl 166-7 — — CH3I 133-5 — — — HCl 176-7 — HCl 177 HBr 194-6 C2H2O4 172 HCl 182-3 dec. Ref. 166 31,32 166 361 361 361 437 480 * 126 200-202 437 511 126 350g 511 200-202 511 52 126 200-202 511 480 * 52
11.15 COOC-H5 11.14 COOCHg 11.15 11.16 11.17 11.18 11.19 11.20 11.21 11.22 12.1 12.2 12.3 12.4 12.5 12.6 12.7 12.8 COO-*-C3H7 COO-/-C3H7 COQ-w-C4H9 COO-/-C4H9 COO-C6H5 COO-CH2- C6H5 CH2—CH2— COO-CH3 COO-CH2- CH2-N(CH3)2 O-OC-CH3 O-OC-CH3 O-OC-CH3 O-OC-CH3 O-OC-CH3 O-OC-CH3 O-OC-C2H5 O-OC-C2H5 H H H J5 H H H H H H H „ CH3 ?? H H H H H 5J CH3 „ CH- H CH3 H H H H H CH3 CH3 H „ H ?J CH3 H H H H „ H „ NX .H.- t"bj NC5H8CH3* C2H5 (bb) N(CH3)2 NC5H10 (b) „ NC5H10 (b) NC4H8O (d) NC5H10 (b) NC5H10 (b) N(CH3)2 N(CHS)2 N(CH3)2 N(CH3)2 N(CH3)2 NC4H8O (d) N(C2H5)2 NC5H10 (b) N(CH3)2 „ N(CH3)2 „ C.iHfclNO. C26H35NO2 C22-H29NO2 C24H31NO2 C24H31NO2 C24H31NO3 C27H29NO2 C28H31NO2 C22H29NO2 C23H32N2O2 C19H23NO2 C20H25NO2 C20H25NO2 C22H25NO3 C21H27NO2 C22H27NO2 C20H25NO2 C21H27NO2 „ b- Iy5-b8 243-5 — — — — — — — m 190-5-1-5 — m 111-4 mlO6 — — m 65-5-5 m 107-8 .— — — — — — — — HCl 161-2 HCl 210-11 HCl 210-11 — — — — 2 HCl 207-8 — C2H4O2 115-8 HCl 203 HCl 102 HCl 196-7 HBr 177-82; HCl O4 154 HCl 205-6 dec.; picrate 176-7 — — HCl 183 propionate 94-6; 1-nicotinate 92-4 HCl 187 HCl 186-7 HCl 177; HC1O4 106-7 (unst.) picrate 142-3 52 166 200-202 511 52 52 52 52 353 166 345, 346 43 258 352 352 20, 21 429, 431 89 258 345, 346 258 302 352 I Z8
Page 1 and 2: S Y N T H E T I C A N A L G E S I C
Page 3: C o n t e n t s Page Preface . . .
Page 7 and 8: I n t r o d u c t i o n THE main pu
Page 9 and 10: 15. 16. 17. 18. 19. 20. 21. CONH2 C
Page 11 and 12: CHAPTER I A n a l g e s i c " Activ
Page 13 and 14: CHAPTER II T h e " A n a l g e s i
Page 15 and 16: METHADONE, MORPHINE, PETHIDINE AND
Page 17 and 18: Symbol ED50 ED50 ED50 ED50 ED50 ED5
Page 19 and 20: CHAPTER III 3 : 3 - D i p h e n y l
Page 21 and 22: o .s HI S T oo HJ * 3 :3-DIPHENYLPR
Page 23 and 24: 2.1 2.2 2.3 2.4 2.5 2.6 OH „ OH O
Page 25 and 26: 2.15 2.16 2.17 2.18 2.19 2.20 2.21
Page 27 and 28: 3.15 4.1 4.2 4.3 4.4 4.5 4.6 4-7 5.
Page 29 and 30: 5.4 5.5 „ 55 » „ CN CN „ „
Page 31 and 32: 5.14 5.15 5.16 5.17 5.18 5.19 5.20
Page 33 and 34: 5.35 5.36 5.37 5.38 5.39 5.40 5.41
Page 35 and 36: 6.9 6.10 6.11 6.12 6.13 6.14 6.15 6
Page 37 and 38: 6.46 6.47 6.48 6.49 6.50 6.51 6.52
Page 39 and 40: 7.4 7.5 7.6 7.7 7.8 7.9 7.10 7.11 C
Page 41 and 42: 7.26 7.27 7.28 7.29 7.30 7.31 7.32
Page 43 and 44: 8,15 8.16 8.17 9.1 9.2 9.3 9.4 9.5
Page 45 and 46: 10.4 1 _ CONi,CH3j, 2 H" HH N CK- N
Page 47: 10.47 10.48 10.49 10.50 10.51 10.52
Page 51 and 52: 13.9 13.10 13.11 CH-C.H5OOC- CH3
Page 53 and 54: 13.13 13.24 13.25 13.26 13.27 13.28
Page 55 and 56: 1-*»1Z c c.:-:f XH 14.13 14.14 14.
Page 57 and 58: 14.56 14.37 14.38 14.39 COCH; COCH3
Page 59 and 60: •> 5 5? 5 5 55 M » I n 5 w 5? )?
Page 61 and 62: 14.49 14.50 14.51 14.52 14.53 14.54
Page 63 and 64: 14.66 14.67 14.68 14.69 14.70 14.71
Page 65 and 66: 14.9" CO-C£H£ 14.98 14.99 14.100
Page 67 and 68: 16.13 16.14 17.1 17.2 17.3 17.4 17.
Page 69 and 70: ti 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8
Page 71 and 72: 2.4 2.5 2.6 2.7 2.8 2.9 2.13 2.14 2
Page 73 and 74: 3.5 3.7 4.1 4.3 4.4 4.5 4.7 5.1 5.2
Page 75 and 76: 5.53 5.59 6.1 6.4 6.8 6.9 6.14 6.18
Page 77 and 78: 3:3-DIPHENYLPROPYLAMINES 71 flo****
Page 79 and 80: 9.19 9.20 9.21 9.22 9.23 9.26 9.27
Page 81 and 82: 10.22 10.23 10.24 10.25 10.26 10.30
Page 83 and 84: 10.42 10.43 10.59 10.60 10.61 10.62
Page 85 and 86: 11.7 11.8 11.9 11.10 11.11 11.12 11
Page 87 and 88: „ — R- 13.10 — CF RT R- CF CF
Page 89 and 90: 13.24 13.25 13.27 13.31 13.33 13,35
Page 91 and 92: 14.36 14.37 14.38 14.39 „ RT RT R
Page 93 and 94: CF RT CF RT ET RB •>•> PRT ET R
Page 95 and 96: 14.41 14.42 14.43 14.44 RB — CF ,
Page 97 and 98: 14.54 14.55 14.56 14.57 14.58 14.59
Page 99 and 100:
14.76 14.77 14.78 14.82 14.83 14.84
Page 101 and 102:
If o ^ 1.1 1.4 1.5 1.6 1.8 1.9 1.10
Page 103 and 104:
3.3 3.4 5.1 5.2 5.3 — — — —
Page 105 and 106:
5.6 5.9 5.12 5.13 5.17 5.27 5.32 5.
Page 107 and 108:
8.8 10.2 10.41 10.43 11.4 11.6 11.9
Page 109 and 110:
14.40 8-99 10-12 d-nci /-base /-bas
Page 111 and 112:
X 14.57 14.64 14.65 14.66 14.69 14.
Page 113 and 114:
Continued from p. 13 3 :3-DIPHENYLP
Page 115 and 116:
3:3-DIPHENYLPROPYLAMINES 109 antisp
Page 117 and 118:
TERTIARY ALCOHOLS 111 halide with a
Page 119 and 120:
TERTIARY ALCOHOLS 113 Tertiary alco
Page 121 and 122:
CHAPTER V S e c o n d a r y A l c o
Page 123 and 124:
5-3 SECONDARY ALCOHOLS 117 C2H5 r n
Page 125 and 126:
SECONDARY ALCOHOLS 119 In the wo-se
Page 127 and 128:
PRIMARY ALCOHOLS reduced (PtO-CH3OH
Page 129 and 130:
NITRILES 123 Basic propyl- and wopr
Page 131 and 132:
NITRILES 125 The following elegant
Page 133 and 134:
NITRILES 127 Nitriles of type [7.1]
Page 135 and 136:
CHAPTER VIII D i a m i n e s a n d
Page 137 and 138:
DIAMINES AND DERIVATIVES 131 Only o
Page 139 and 140:
PRIMARY AMIDES ^ ^NH—CH—CH—N'
Page 141 and 142:
PRIMARY AMIDES 135 Quaternization b
Page 143 and 144:
ACIDS AND ACID CHLORIDES 137 When h
Page 145 and 146:
CHAPTER XI S e c o n d a r y A m i
Page 147 and 148:
CHAPTER XII R 8 7 5 a n d R e l a t
Page 149 and 150:
TERTIARY AMIDES 143 The relation be
Page 151 and 152:
TERTIARY AMIDES 145 (1) In man R 87
Page 153 and 154:
ESTERS DERIVED FROM AMINO ACIDS 147
Page 155 and 156:
ESTERS DERIVED FROM AMINO ACIDS 149
Page 157 and 158:
CHAPTER XV Esters derived f r o m S
Page 159 and 160:
Nomenclature of derived isomers Mel
Page 161 and 162:
CHAPTER XVI K e t i m i n e s , A c
Page 163 and 164:
NAA'* N(CH3)2 „ 55 ?? ?5 *s 5 N(C
Page 165 and 166:
KETIMINES, ACYL KETIMINES AND KETON
Page 167 and 168:
CHAPTER XVIII S u l p h o n e s (I:
Page 169 and 170:
SULPHONES 163 According to KLENK et
Page 171 and 172:
OTHER COMPOUNDS OF STRUCTURE (I) 16
Page 173 and 174:
DISSOCIATION CONSTANTS Steric facto
Page 175 and 176:
R CONFIGURATIONAL STUDIES TABLE XVI
Page 177 and 178:
REFERENCES 1 ADAMI E. and MARAZZI E
Page 179 and 180:
REFERENCES 173 89 CHEN K. K. (1948)
Page 181 and 182:
REFERENCES 175 163 FRIEBEL H. and R
Page 183 and 184:
REFERENCES 177 249 KEATS A. S. and
Page 185 and 186:
REFERENCES 179 339 MOFFETT R. B. (1
Page 187 and 188:
REFERENCES 181 411 SCHULTZ E. M., R
Page 189:
REFERENCES 183 499 WHEATLEY W. B.,
show all

CO-NH2 CO-NH2 â€žâ€žCO-NH2 CO-NH2

Create successful ePaper yourself

Delete template?

Save as template?