PiCCO based algorithms - PULSION Medical Systems SE
PiCCO based algorithms - PULSION Medical Systems SE
PiCCO based algorithms - PULSION Medical Systems SE
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11.06.2010 / 3<br />
Prospective Trial of Supranormal Values of Survivors as<br />
Therapeutic Goals in High-Risk Surgical Patients*<br />
William C. Shoemaker, M.D.; Paul L. Appel, M.PA; Harrq B. Kram, M.D.; Kenneth<br />
Waxman, M.D; and Tai-Shion Lee, M.D., F.C.G.P<br />
� High risk patients (n=340)<br />
� Study 1: n=252 patients (n=151 controls,<br />
n=101 GDT), dependend on on call rota<br />
�GDT: DO2 >600 ml·min-1 ·m-2 , CI >4.5<br />
L·min-1 ·m-2 �Controls: DO2 400-550 ml·min-1 ·m-2 , CI<br />
2.8-3.5 L·min-1 ·m-2 � Study 2: n=88 patients, randomised<br />
� Primary endpoint: in-hospital mortality<br />
Mortality Patients (%)<br />
40<br />
30<br />
20<br />
10<br />
0<br />
Control1<br />
*<br />
Protocol 1<br />
Control 2<br />
Protocol 2<br />
*
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