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CURRICULUM VITAELOIS W. CHOI-KAIN M.D. P.1PART I: GENERAL INFORMATIONName: Lois Wonsun Choi-KainOffice Address: McLean Hospital, 115 Mill Street, Belmont, MA 02478Office Telephone: 617-855-3933 Office Fax: 617-855-3748E-mail: lchoikain@partners.orgEducation:1996 Bachelors in Arts, Social Studies, Harvard-Radcliffe College1998 Master’s Degree in Education, Harvard Graduate School of Education2002 Doctorate in Medicine, Thomas Jefferson UniversityPostdoctoral Training:2002-2003 Internship in Preliminary Medicine, Carney Hospital2003-2006 Resident in Psychiatry, Massachusetts General Hospital/McLean Hospital AdultPsychiatry Residency Program2005-2006 Chief Resident in Psychiatry, McLean Hospital2006-2008 Psychosocial Fellow, McLean Hospital2006-2009 Program for Minority Research Training in Psychiatry (PMRTP) Fellow,American Psychiatric Institute for Research and Education (APIRE) and NationalInstitute for Mental Health (NIMH)Licensure and Certification:2005 Full Medical License, Commonwealth of Massachusetts2006 Certificate of Completion, Psychoanalytic Research Training Program, AnnaFreud Centre Program at the Child Study Center.2006 Certificate of Attendance and Certificate of Reliability, Adult AttachmentTraining Institute, University College of London.2006 Certificate of Attendance, Mentalisation Based Therapy Workshop, The AnnaFreud Center2007 Certification in the Speciality of Psychiatry, American Board of Psychiatry andNeurology2007 Certificate of Attendence, Reflective Function Training Course, The Anna FreudCenter2008 Certification of Reliability, Adult Attachment Interview (AAI) by Drs. MaryMain and Eric Hesse. Teachers Deanne and David Pedersen Ph.D.sAcademic Appointments:2002-2003 Clinical Fellow in Medicine, Tufts University School of Medicine2003-2006 Clinical Fellow in Psychiatry, Harvard Medical School2006- Clinical Instructor in Psychiatry, Harvard Medical SchoolHospital Appointments:2003-2006 Resident in Psychiatry, Massachusetts General Hospital and McLean Hospital2006-2007 Chief Administrative Resident, McLean Hospital2006- Assistant Psychiatrist, McLean Hospital2009- Medical and Program Director, Gunderson Residence of McLean Hospital1

CURRICULUM VITAELOIS W. CHOI-KAIN M.D. P.2Major Administrative Responsibilities:2004-2006 Chair, Adams House Premedical Advisory Committee, Harvard University2005-2006 Administrative Chief Resident, McLean Hospital2006-2007 Executive Board, Association of Women Psychiatrists (AWP)2006-2009 Chair, McLean-SAMHSA Cultural Grand Rounds Series Committee2006- Co-Chair, Stanton Lecture Committee2007- Member, Fellowship Committee, American Psychoanalytic Association2009-2010 Chair, Research Seminar, American Psychoanalytic Association Fellowship2009-2010 MGH-McLean Adult Psychiatry Residency Selection Committee, MemberProfessional Societies:2004- Massachusetts Psychiatry Society, Member2004- American Psychiatric Association, Member2006-2007 Association of Women Psychiatrists, Board Member2006-2008 American College of Psychiatrists, Laughlin Fellow2007-2011 American Psychoanalytic Association, MemberAwards and Honors:2000 First Prize, Alpha Omega Alpha Essay Contest2002 Baldwin L. Keyes Prize in Psychiatry2005 American Group Psychotherapy Scholarship2005 Frieda Fromm-Reichmann M. D. Memorial Award, American Association ofDirectors of Psychiatric Residency Training and the Endowment for theAdvancement of Psychotherapy2005-2006 SAMHSA Minority Fellowship, American Psychiatric Association2005-2006 Psychoanalytic Fellowship, American Psychoanalytic Association2005-2007 Laughlin Fellowship, American College of Psychiatrists2006-2007 Alexandra and Martin Symonds Foundation Fellowship, Association of WomenPsychiatrists2006 Merit Award, The Dr. Henry P. and M.Paige Durkee Laughlin Foundation2007 Travel Award, American College of Neuropsychopharmacology2009 Partners in Excellence AwardPART II: RESEARCH, CLINICAL, AND TEACHING CONTRIBUTIONSResearch Funding Information:2005-2006 APA/SAMHSA Minority FellowshipWith funding from the APA/SAMHSA Minority Fellowship, I developed acultural grand round series at McLean Hospital focused on expanding theMcLean community’s understanding of how to understand cultural and racialfacets of experience and identity from a psychodynamic viewpoint. Dr. SalmanAkhtar, was the inaugural speaker, scheduled October 5 th , 2006, the secondspeaker Dr. Neil Altman in February of 2008, and the third Dr. Kimberlyn Learyon February 9, 2009.2006-2008 American Psychiatric Institute for Research and Education, Program for MinorityResearch Training. Psychosocial Fellowship, McLean Hospital.These two funding sources have supported by salary as a research fellow for theperiod of 2006-2008. Under the mentorship of Drs. John Gunderson and Karlen2

CURRICULUM VITAELOIS W. CHOI-KAIN M.D. P.3Lyons-Ruth, I am coordinating a study of attachment behaviors in subjects withand without BPD and their mothers. This study uses rigorously diagnosedsamples from Dr. Gunderson’s ongoing family study that include BPD andnormal control subjects and their mothers. Mother-daughter dyads participate inan experimental protocol that involves a video-taped 10 minute conflictdiscussion between mothers and daughters. We are investigating the relationshipbetween markers of attachment behaviors in the video-taped conflict discussionwith BPD. Also, we are studying the functioning of the hypothalamic-pituitaryadrenalaxis in response to this interpersonal stressor by obtaining baselinesalivary cortisol samples at the start of the lab visit, a reactive sample 20 minutesafter the start of the conflict discussion, and a recovery sample 40 minutes afterthe start of the conflict discussion. Our hypotheses are that 1) BPD will beassociated with markers of disorganized attachment and 2) disorganizedattachment will be associated with dysregulated stress responses in the HPA axischaracterized by an absence of expected decreases in salivary cortisol in therecovery samples.2007-2009 Fund for Psychoanalytic ResearchThis $40,000 grant funds a pilot study aimed to assess the relationship betweenattachment status, neurocognition, and social cognition in Borderline PersonalityDisorder(BPD). BPD has been distinguished by three realms of disturbance:affect regulation, behavioral control, and disturbed relationships. The symptomsrelated to disturbed relationships in BPD provide the greatest diagnostic value,demonstrate significant familiality and heritability, and may represent a majorunderlying phenotype of the disorder. In the realm of disturbed relationships,BPD has been both theoretically and empirically associated with preoccupied andfearful insecure attachment types. While previously published research hasestablished increased rates of attachment insecurity in BPD samples, themechanism by which attachment insecurity develops into the syndrome of BPDis not well understood. One theoretical model of BPD proposes that earlyattachment insecurity interferes with the development of critical social cognitiveskills such as mentalization, defined as the capacity to understanding one’s ownand other people’s mental states. The neuroscientific literature on BPD suggeststhat difference in brain structure and function underlie key clinical features ofBPD, which raises the question of whether deficits in neuropsychologicalfunction are determinants of social cognitive skills, and are thereby implicated inthe interpersonal disturbances in BPD. This application proposes a pilot studyaimed to assess the relationship between attachment status and 1) BPD and itsphenotypes, 2) neuropsychological skills, and 3) social cognitive skills. Ourmethods will involve administration of the Adult Attachment Interview (AAI), abrief but comprehensive neuropsychological battery, and assessments of socialcognitive skills relevant to mentalization to 60 rigorously diagnosed and wellcharacterizedfemale subject (30 subjects with BPD and 30 without BPD)ascertained from John Gunderson and Mary Zanarini’s ongoing family study ofpersonality traits (NIMH R01 MH070377-01A2). These pilot data will besummarized and prepared for both publication and application to federal andprivate funding sources for larger scale research.3

CURRICULUM VITAELOIS W. CHOI-KAIN M.D. P.4Report of Teaching: Local Contributions:Massachusetts General Hospital:2005 Lecture, psychosomatics conference, Massachusetts General Hospital: “IntimacyHostility, and Development: Psychodynamic Dimensions of C-L Psychiatry”with discussant John Querques, M.D.2006 Lecture, Senior Talks, Massachusetts General Hospital: “Who’s the Boss:Agency and Authority in Psychiatric Treatment”2007 Lecture, Resident Report, Massachusetts General Hospital: “Attachment andBorderline Personality Disorder: Theory, Research, and Clinical Implications.”2007 Discussant, Psychosomatics Conference: “TFP and BPD: The Future ofPsychotherapy and Personality Disorders Research”McLean Hospital:2005 Research presentation, Center for Adult Development, McLean Hospital,“Culture and Personality Disorders”2005 Case Presentation, Stanton Lecture Case Conference, McLean Hospital, “A Caseof Borderline Personality Organization and Narcissistic Personality” withdiscussant Otto Kernberg, M.D.2005 Research presentation, Center for Adult Development, McLean Hospital,“Attachment, Mentalization, and Borderline Personality Disorder”2006 Presentation, Borderline Center Case Conference, McLean Hospital,“Attachment, Mentalizations, and MBT”2007 Presentation, Center for Adult Development, McLean Hospital, “Attachment andBorderline Personality Disorder in the Family Study of Personality Traits”2007- Lecture series, Harvard Medical School, Clinical Rotation at McLean“Interviewing and Personality Disorders”2009- Course Director, “Psychotherapy for Borderline Personality Disorder: AnIntensive Training in the Mentalization Based Treatment Approach, with FacutyJohn G. Gunderson MD, Anthony Bateman MD, and Peter Fonagy PhD, January2010, October 2010.2010 Cultural Grand Rounds, “Perspectives on Cross-Cultural Applications ofPsychiatry: A Mentalization Based Model”2010 Presentation, Borderline Center Case Conference, McLean Hospital, “ApplyingDBT in the Case of a High Functioning Patient with BPD”4

CURRICULUM VITAELOIS W. CHOI-KAIN M.D. P.5Other Invited Presentations:2005 Panel member, “Cross-Cultural Views of Community,” at The Association forPsychoanalysis of Culture and Society 2005 Meeting “Culture and Society,”November 20052006 Presenter, “On Self-Disclosure,” with discussant Jody Messler Davies, Ph.D. atthe American Psychoanalytic Association 2006 Winter Meeting, January 20062010 Presenter and Panel Chair, “The Developmental Process of Becoming aPsychiatrist: Immigration, Regression, and Metamorphosis” at the AmericanAssociation of Directors of Psychiatric Residency Training 2006 meeting.2006 Presenter, “Attachment, Mentalization, and Borderline Personality Disorder: TheDevelopment of an Alternative Measure for Reflective Function,” withdiscussant Kenneth Levy, Ph.D. at the Yale Center for Child Study/ Anna FreudCenter Research Training Program, March 20062008 Presenter, “A Way of Listening: Case Conceptualization andTreatment Planning in the Initial Sessions,” with Mary Jo Peebles-Kleiger, Ph.D.at The American Psychoanalytic Association Spring 2006 Meeting Washington,DC, June 20062007 Chair, “Race, Culture, and Treatment,” with Kimberlyn Leary, Ph.D. at TheAmerican Psychoanalytic Association Spring 2007 Meeting New York, NewYork, January 20072007 Chair and Presenter, “New Perspectives on Psychodynamic Treatments forBorderline Personality Disorder,” with John Gunderson, M.D.; AnthonyBateman, M.D.; Otto Kernberg, M.D.; John Clarkin, Ph.D.; and discussant GlenGabbard, M.D. F.A.C.Psych at The American Psychiatric Association 2007Annual Meeting, May 20072007 Presenter, “Case Conference 1,” with John Gunderson, M.D. & GlenGabbard, M.D. at The American Psychiatric Association 2007 AnnualMeeting, May 20072008 Presenter, Grand Rounds, “Attachment and Borderline Personality Disorder:Theory and Evidence,” Massachusetts Mental Health Center.2008 Chair and Presenter, “The Scientific Basis of Interpersonal Dysfunction inBorderline Personality Disorder,” with John Gunderson, M.D.; Karlen Lyons-Ruth, PhD.; Peter Fonagy, Ph.D.; John Clarkin, Ph.D.; and discussant GlenGabbard, M.D. F.A.C.Psych at The American Psychiatric Association 2008Annual Meeting, May 20082009 Presenter, “Familial Aggregation of Attachment in Borderline PersonalityDisorder” in Symposium “The Transmission of Borderline Personality Disorder”with John Gunderson, M.D.; Mary Zanarini, Ed.D; James Hudson, M.D. M.P.H.D.Sc; and Larry Siever, M.D. at The American Psychiatric Association 2009Annual Meeting, May 20095

CURRICULUM VITAELOIS W. CHOI-KAIN M.D. P.62010 Chair, “Personality Disorders: Cross-Fertilization of Psychoanalysis andDescriptive Psychiatry,” Discussants Otto Kernberg and Glen Gabbard,American Psychoanalytic Association Winter Meeting, January 20102010 Presenter, “A Comprehensive Integrated Curriculum for Cutting EdgeTreatments for Borderline Personality Disorder,” AADPRT Annual Meeting,March 20102010 Presenter, “Practical Priorities in Psychiatric Case Management of BorderlinePersonality Disorder,” Florida Psychiatric Society Spring Meeting, May 2010PART III: BIBLIOGRAPHYOriginal Articles:Choi LW. Affirmative action in medical education: Minority underrespresentation inmedicine. The Pharos of Alpha Omega Alpha. 2000; 63: 4-9.Choi LW. Reply to Letters to the Editor. The Pharos of Alpha Omega Alpha, 2001; 64: 46-47.Akhtar S, Choi LW. When evening falls: The immigrant’s encounter with middle and oldage. The American Journal of Psychoanalysis. June 2004; 64: 183-191.Choi-Kain LW. A tale of two mentors. Ed. Glen Gabbard. Psychiatric Times. December2005; 23: 15-16.Choi-Kain LW, Pope HG. Atypical" neuroleptic malignant syndrome and its relatives:possibly underreported, probably underrecognized, and certainly dangerous. HarvardReview of Psychiatry 2007; 15(4): 181-186.Choi-Kain LW, Gunderson JG. Mentalization: Ontogeny, assessment, and application in thetreatment of borderline personality disorder. Am J Psychiatry 2008; 165:1127-1135Zimmerman DJ, Choi-Kain LW. The Hypothalamic-Pituitary-Adrenal Axis in BorderlinePersonality Disorder: A Review. Harvard Review of Psychiatry 2009; 17: 167-183.Choi-Kain LW, Gunderson JG. Borderline personality disorder and resistance to treatment.Psychiatric Times 2009; 26.Choi-Kain LW, Fitzmaurice GF, Zanarini MC,Laverdiere O, Gunderson JG. The relationshipbetween self-reported attachment styles, interpersonal dysfunction, and borderlinepersonality disorder. J Nerv Ment 2009; 197: 816-821.Choi-Kain LW, Zanarini MC, Frankenberg FR, Fitzmaurice GF, Reich DB. A LongitudinalStudy of the 10-Year Course of Interpersonal Features in Borderline PersonalityDisorder. J Pers Disorders 2010; 24(3): 365-376.6

CURRICULUM VITAELOIS W. CHOI-KAIN M.D. P.7Book Chapters:Kim L, Choi-Kain LW. Personality Disorders. In Rosenquist et al., (Eds.), TheMassachusetts General Hospital/ McLean Hospital Residency Handbook of Psychiatry.Philadelphia, PA: Lippincott, Williams, & Wilkins, 2009.Choi-Kain LW. Second Generation Korean Americans. In Akhtar S (Ed.), Freud and the FarEast: Psychoanalytic Perspectives on the People and Cultures of China, Japan, and Korea.Northvale, NJ: Jason Aronson, 2009.Posters:Choi-Kain LW, Laverdiere O, Gunderson JG, Zanarini MC. Investigating attachmentdisturbances as the basis of interpersonal dysfunction in borderline personality disorder.Presented at the Annual Meeting of the American College of Neuropsychopharmacology,December, 2007.Choi-Kain LW, Laverdiere O, Gunderson JG, Zanarini MC. The relationship between selfreportedattachment styles, interpersonal dysfunction, and borderline personality disorder.Presented at the Winter Meetings of the American Psychoanalytic Association, January,2008.Ackerman JA, Choi-Kain LW, Gunderson JG, Zanarini MC. Attachment, cognition, andborderline personality disorder. Presented at the Winter Meetings of the AmericanPsychoanalytic Association, January, 2009.7