oXiris membrane - CRRT Online

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Clinical studies resultsposter - SRLF, January 2007:Prospective ST100 without heparin compared to retrospectiveM100 *Prospective data on Prisma, ST100 pre without heparin in ECC45 sets, 33.33% censored data,Median lifespan: 20h05 - 0.42h to 69.67hRetrospective data, on Prisma M100 pre with or without heparin inECC45 sets, 22.22% censored dataMedian lifespan: 16h35 - 0.67h to 66.75 hEven if “median lifespan” is superior for ST, no significant difference wasevidenced: a study including more patients is necessary to demonstrate asignificant lifespan increase (see next slide).* Hopital de La Croix-Rousse, Lyon - Pr GuerinGambro Clinical study report, December 2006 - Study 1434.
Sets SurvivalSurvival curves for selectedRetrospective vs Prospective sets1,000,900,800,70M100ST1000,600,500,400,300,200,100,00Group:0 3 6 9 12 15 18 21 24 27 30 33 36 39 42 45 48 51 54 57 60 63 66 69Retrospective group treated with AN69Prospective group treated with AN69 STTime (hours)Lifetime Study for prospective and retrospective filters - EFFI-STAT - F. MARTEAU - MFIG1 - 24MAR06* Hopital de La Croix-Rousse, Lyon - Pr GuerinGambro Clinical study report, December 2006 - Study 1434.
Page 1: AVOIDING ANTICOAGULATION in CRRT: A
Page 4 and 5: Patient at high risk of bleeding•
Page 6 and 7: Heparin or CitrateSaline FlushesHep
Page 8 and 9: oXiris: Unique Membrane Technologyh
Page 10: ‗Bio-activity‘ of the Grafted H
Page 16 and 17: Reported average filter life withAN
Page 18 and 19: AN69ST compatibility of use with ci
Page 20 and 21: EndotoxinEU/mlDoes the surface coat
Page 22 and 23: Clots in deaeration chamber• Like
Page 25: Conclusions & Perspectives‣ Modif

oXiris membrane - CRRT Online

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