1. Directory of Clinical Research Centres/Facilities in Ireland

Name/LocationNational Children'sResearch Centre.Our Lady'sHospital, Crumlin,Dublin Link toWebsiteICRIN Directory of Clinical Research Centres/Facilities in IrelandDUBLINContact Director DateOpenedDr. Sinéad Nic An Fhailí(Nally)Clinical Research ProjectManagerNational Children’sResearch CentreOur Lady’s Children'sHospital, CrumlinDublinTel: +353 1 409 6806Email:sinead.nally@ncrc.ieProf. Carlos BlancoDirector of ResearchNational Children’sResearch CentreOur Lady’s Children'sHospital, CrumlinDublinTel: +353 1 4096585Email:carlos.blanco@ncrc.ieDr. Jacinta KellyDeputy Director ofResearchTel: +353 1 4096583Email:jacinta.kelly@ncrc.ieDr. Colm O'DonnellClinical DirectorTel: + 353 1 6373186codonnell@nmh.ieMain Features1965 • Two-bed clinical assessmentroom (e.g. for use in medicinesfor children studies)• Patient Proximate SamplePreparation Room• Research Laboratory (tissueculture suite, PCR room,microbiology room, confocalmicroscopy suite, flowcytometry etc)• Access to support staff (clinicalresearch management, datamanagement, researchnurses/assistants, clinical trialspharmacist, medical sciencelaboratory personnel)Office and Reading Space forClinical and TranslationalResearchersServices• Paediatric Research Support• Protocol Design• CRF Design• Regulatory/EthicsSubmissions• Informed Consent /AssentAdvice• Trial Master File (TMF)Maintenance• Project ManagementSupport• Data Management Support• Pharmacy Support• Statistical Support• Medical Review• Independent DataMonitoring Committee• PI identification• Feasibility assessment• Patient recruitment• Pharmacovigilance• Biobanking• Case Cohort - ClinicalInvestigations - Clinical Trials

ICRIN Directory of Clinical Research Centres/Facilities in IrelandName/LocationRoyal College ofSurgeons Ireland(RCSI) ClinicalResearch Centre.BeaumontHospital, DublinLink to WebsiteDUBLINContact Director DateOpenedDeirdre HylandDirector of NursingClinical Research Centre,Smurfit Building,Beaumont HospitalDublin 9Telephone: +353 (1)8093785Email: dhyland@rcsi.ieProf. Dermot KennyClinical Research Centre,Smurfit Building,Beaumont HospitalDublin 9Telephone: +353 (1)8093780Email: dkenny@rcsi.ieMain Features2001 • Four consultation/clinicalassessment rooms• Four Bed Inpatient Unit• Two Inpatient rooms• Sample Processing Laboratory• Biobanking Facility• Gene Therapy UnitServices• Phase I volunteer studies• Protocol Design• Regulatory/Ethicssubmissions• Trial Master File (TMF)• Insurance/Indemnity• Contract negotiation• Project Management• Medical Review• Independent DataMonitoring Committee• PI identification• Feasibility assessment• Patient recruitment• Patient treatment as perprotocol• Nurse Research Education• Case Report Form (CRF)completion• Pharmacovigilance• Pharmacoeconomics/ Reimbursement• Biobanking

ICRIN Directory of Clinical Research Centres/Facilities in IrelandName/LocationWellcome Trust -HRB ClinicalResearch Facility,Trinity CollegeDublinSt James'sHospital, DublinDUBLINContact Director DateOpenedJeremy TownsProgramme ManagerTrinity Centre for HealthSciencesSt James's HospitalDublin 8Tel: +353 (1) 8964537Email: townsj@tcd.ieProf. Michael Gill ClinicalDirectorWellcome Trust/HRB CRFat St James's HospitalTrinity Centre for HealthSciencesSt James's HospitalDublin 8Tel: +353 (1) 896 2241Fax: +353 (1) 896 3405Email: mgill@tcd.ieProf. Colm BerginAssociate DirectorClinical Professor ofMedicine, St James'sHospitalDublin 8Tel: +353 (1) 4162507Email: cbergin @stjames.ieMain Features2013 • Four inpatient rooms• Six-Bed Day Unit• Four Multipurposeconsultation/examination rooms• Neurophysiology Suite• Research Pharmacy/ AsepticClean room for Gene Therapypreparation• Sample processing laboratory• Office Space• Bioengineering Workshop• Seminar and Meeting rooms• Staff changing rooms• Adjacent to 3T research MRI(CAMI)Services• Protocol Design• Regulatory/Ethicssubmissions• Trial Master File (TMF)• Insurance/Indemnity• Contract negotiation• Project Management• Medical Review• Independent DataMonitoring Committee• PI identification• Feasibility assessment• Patient recruitment• Patient treatment as perprotocol• Case Report Form (CRF)completion• Pharmacovigilance• Pharmacoeconomics/ Reimbursement• Biobanking• Medical Imaging

Name/LocationUniversity CollegeDublin, ClinicalResearch Centre.(1) MaterMisericordiaeHospital Dublin,(2) St Vincent'sHospital, DublinLink to WebsiteICRIN Directory of Clinical Research Centres/Facilities in IrelandDUBLINScientific Director Director DateOpenedDr Peter DoranDirector UCD CRCsUCD CRC MaterMisericordiae UniversityHospital21 Nelson StreetDublin 7UCD CRCSt Vincent's UniversityHospitalElm ParkDublin 4Tel: +353 1 7164587Email:peter.doran@ucd.ieProf. Patrick MurraySchool of Medicine &Medical ScienceMater HospitalEccles StreetDublin 7Tel: +353 (1) 7166319Email:patrick.murray@ucd.ieProf. Michael KeaneSt Vincent's HospitalElm ParkDublin 4Tel: +353 (1) 2214574Email:michael.p.keane@ucd.ieMain Features2006 • Four consultation/clinicalassessment rooms• Two procedure rooms• IMP storage facilities• Sample processing laboratory• Cell culture suite• General laboratory• Biobanking facility• Dexa scanner• Data Centre2007 • Four consultation/clinicalassessment rooms• Two Procedure Rooms• IMP storage facilities• Sample processing laboratory• Biobanking facility• Biomarker Core Lab• Endoscopy Suite• Recovery room• Remote Monitoring roomServices• Protocol Design• Regulatory/Ethicssubmissions• Trial Master File (TMF)• Insurance/Indemnity• Contract negotiation• Project Management• Medical Review• Independent DataMonitoring Committee• PI identification• Feasibility assessment• Patient recruitment• Patient treatment as perprotocol• Case Report Form (CRF)completion• Pharmacovigilance• Pharmacoeconomics/ Reimbursement• Biobanking

ICRIN Directory of Clinical Research Centres/Facilities in IrelandName/LocationHealth ResearchBoard, ClinicalResearch FacilityGalway (CRFG),University HospitalGalway Link toWebsiteGALWAYContact Director DateOpenedLisa DalyProgramme ManagerGeata an Eolais,University Road, Galway.Telephone +353 91495891Email:lisa.daly@nuigalway.ieProf. Frank GilesDirectorGeata an Eolais, UniversityRoad, Galway.Telephone +353 91 495970Email:frank.giles@nuigalway.ie2008(Currentlysupportingclinicalresearchand clinicaltrials)Main FeaturesNew building completionscheduled 2013 with followingfeatures:• 4 inpatient rooms: 2 2-bed, 2single bed• Day ward with 5 beds• Recovery area with 3 beds• Research Pharmacy• Endoscopy Suite• Endocrine Suite• Non-Invasive cardiology Suite• Pulmonary function testing Suite• Minor Procedures room• Phlebotomy room• Cell/gene therapy preparationroom• 7 consultation/exam rooms• Dietetics Kitchen• Specimen sorting area• Laboratory/ biobanking facilities• Cell culture laboratory• Clinical research laboratory• Biometrics Unit• Office and seminar spaceServices• Protocol Design• Regulatory/Ethics submissions• Trial Master File (TMF)• Insurance/Indemnity• Contract negotiation• Project Management• Medical Review• Independent Data MonitoringCommittee• PI identification• Feasibility assessment• Patient recruitment• Patient treatment as perprotocol• Case Report Form (CRF)completion• Research Pharmacist• Pharmacovigilance• Pharmacoeconomics/ Reimbursement• Biobanking• Data Management• eCRF design• Statistics