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40TH ANNUAL ESDR MEETING - ESDR 2010

40TH ANNUAL ESDR MEETING - ESDR 2010

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EUROPEAN IMMUNODERMATOLOGy SOCIETy <strong>MEETING</strong><br />

Wednesday 8 September <strong>2010</strong>, 14.00-17.30<br />

FENNIA II ROOM<br />

Chair: Richard Groves (London)<br />

Program<br />

14.00-14.05 Introduction and welcome<br />

Richard Groves (London)<br />

14.05-14.17 IL-20, IL-21 and p40: Potential Biomarkers of Treatment Response for Ustekinumab<br />

anne Gedebjerg (aarhus)<br />

14.17-14.29 Expression of pattern recognition receptors in normal and inflamed human epidermis:<br />

upregulation of dectin-1 in psoriasis<br />

Heleende Koning (nijmegen)<br />

14.29-14.41 Fumarates improve Psoriasis and Multiple Sclerosis by inducing type II dendritic cells<br />

Jürgen Brück (Tübingen)<br />

14.41-14.53 Increase in IL-17A and IL-22 producing CD8 T cells in lesional psoriatic skin<br />

Pieter Res (amsterdam)<br />

14.53-15.05 Differential capacity of human skin dendritic cell populations to polarize naïve T cells<br />

into IL-17, IL-21 and IL-22 producing cells<br />

Karine Penel-sotirakis (Lyon)<br />

15.05-15.17 Formation of DC-Treg aggregates depends on adenosine<br />

sabine Ring (Heidelberg)<br />

15.17-15.29 Lesional skin of patients with chronic atopic dermatitis shows increased proportions of<br />

IL-31 positive T cells and a Th2/Th22 dominance<br />

Krisztina szegedi (amsterdam)<br />

15.29-15.41 Decreased TNF-alpha synthesis by macrophages restricts cutaneous<br />

immunosurveillance by memory CD4+ T cells during ageing<br />

elaine agius (London)<br />

15.41-16.05 Coffee Break<br />

16.05-16.17 Tissue derived ATP activates CD4+CD25+FoxP3+ regulatory T cells and stimulates its<br />

own degradation to immunosuppressive adenosine during contact hypersensitivity<br />

reactions<br />

Karsten Mahnke (Heidelberg)<br />

16.17-16.29 The contact allergen 2,4-dinitrochlorobenzene does not affect microRNAs’ -155, -125b<br />

and -146a expression in skin explants, keratinocytes and monocyte derived dendritic cells<br />

eirini Vavatsikou (southampton)<br />

16.29-16.41 FcgammaRIV Promotes, while FcgammaRIIB Protects from Autoantibody-induced<br />

Tissue Damage in Autoimmunity to Type VII Collagen<br />

Michael Kasperkiewicz (Lübeck)<br />

16.41-16.53 Anti-desmocollin autoantibodies in pemphigus herpetiformis and pemphigus vegetans.<br />

IgG antibodies to desmocollins 1-3 are the key factor for their characteristic phenotypes<br />

norito Ishii (Kurume, Japan)<br />

16.53-17.05 Towards a better understanding of paraneoplastic pemphigus pathogenesis:<br />

identification of the p170 antigen recognized by PNP autoantibodies<br />

Isabelle schepens (Bern)<br />

17.05-17.17 Human monoclonal antibodies bind desmoglein 3 epitopes shared by pemphigus<br />

vulgaris patient autoantibodies and synergistically induce loss of adhesion between<br />

keratinocytes<br />

Valentina Calabresi (Rome)<br />

17.17-17.29 The vast majority of pemphigus vulgaris patients possess circulating autoantibodies<br />

reacting with an immunodominant epitope on desmoglein 3<br />

Giovanni Di Zenzo (Rome)<br />

This satellite meeting is free to all registered esDR delegates.<br />

31<br />

EIS <strong>MEETING</strong>

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