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Issues in Randomization Outline

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Randomize 56, 3 TimesSimple <strong>Randomization</strong>1 2 3N/arm 28:28 38:18 17:39Red 9 4:5 6:3 2:7Orange 8 4:4 7:1 4:4Yellow 3 2:1 1:2 1:2Blue 11 5:6 5:6 3:8Green 16 10:6 10:6 4:12Black 9 3:6 9:0 3:6Randomize 20, 5 TimesSimple <strong>Randomization</strong>1 2 3 4 5N/arm 9:11 9:11 11:9 6:14 14:6Red 4 2:2 2:2 2:2 0:4 3:1Orange 5 1:4 2:3 2:3 2:3 4:1Yellow 4 2:2 2:2 3:1 0:4 2:2Blue 2 2:0 1:1 1:1 1:1 2:0Green 3 1:2 1:2 2:1 1:2 2:1Black 2 1:1 1:1 1:1 2:0 1:1Block <strong>Randomization</strong>• Try aga<strong>in</strong>• Use (simple) Block <strong>Randomization</strong>14

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