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Issues in Randomization Outline

Issues in Randomization Outline

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Software• Most is expensive and some haveyearly license fees– NIH (through CIT) many times has thesoftware for free or cheaper thanretail; CDC and universities do, too• Some is hard to use, some is easySoftware: Programm<strong>in</strong>g Options• S-PLUS (W<strong>in</strong>dows/UNIX): Strongacademic and NIH follow<strong>in</strong>g;extensible; comprehensive– www.<strong>in</strong>sightful.com• R (W<strong>in</strong>dows/L<strong>in</strong>ux/UNIX/Mac): GNU;similar to S-PLUS– www.r-project.org– www.bioconductor.orgS+ and R• Produce well-designed publicationqualityplots• Code from C,C++, Fortran can becalled• Active user communities32

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