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#63 Outcome Study of Gutta-Percha and ResilonTM Filled Root Canals: A Radiographic andClinical AnalysisA. TEHRANY 1 , E.M. RIVERA 1 , F.B. TEIXEIRA 2 , and D.J. CAPLAN 31 University of North Carolina, Chapel Hill, 2 University of Texas Dental School, San Antonio, 3 University of Iowa,Iowa City, IAThe purpose of this study was to evaluate the clinical and radiographic outcome of teeth diagnosed as havingNecrotic Pulp with Chronic Apical Periodontitis when root canal treated and filled with ResilonTM. It washypothesized that endodontically treated teeth filled with ResilonTM would have similar clinical and radiographicoutcomes of success as those found in previous studies utilizing gutta-percha as the filling material. Patientsreceived standardized endodontic treatment by undergraduate dental students in a university setting; 45 teeth wererecalled after a minimum of 12 months. A clinical assessment based on symptoms and diagnostic tests and aradiographic assessment comparing pre-operative and follow-up radiographs using the Periapical Index wereperformed. The teeth were classified as healed, healing or not healed. Patients presenting with complaints of pain,the presence of swelling and/or sinus tract, sensitivity to percussion and/or palpation, attachment loss greater than5mm, tooth mobility greater than +1 and/or a periapical radiolucency on the radiograph that was equal to or largerthan the initial pre-operative image were classified as not healed. Patients who presented with none of the aboveand a decreased size of the periapical radiolucency were classified as healing and those with complete resolutionof the periapical radiolucency were classified as healed. Initial findings indicate that endodontically treated teethfilled with ResilonTM show outcomes of success similar to previous studies employing gutta-percha. Anadditional finding indicated that teeth classified as not healed showed a tendency to be attributed to delay and/orlack of a permanent coronal restoration following root canal therapy.#64 The Impact of Caregiver Oral Health Literacy on Children’s Oral Health OutcomesE.K. MILLER, J.Y. LEE, D DeWalt and W.F. VANN Jr.Departments of Pediatric Dentistry and Medicine, UNC Schools of Medicine and DentistryThis investigation is a prospective cross-sectional study that will assess the relationship of the primary caregiver’soral health literacy and the child’s oral health outcomes. This investigation will discern the role of literacy in oralhealth outcomes and will determine if parental literacy skills are related to poor oral health knowledge, behaviorsand children’s oral health status or if disparities still remain among individuals with equivalent literacy levels. Thespecific aims are 1) to examine the relationship between oral health literacy and oral health behaviors, oral healthknowledge and the primary caregiver’s reports of the child’s oral health status and 2) to examine literacy as apredictor of a) minimal or no disease versus b) advanced disease requiring 3-4 restoration appointments. Indisentangling the relationships between literacy, behavior, knowledge, and outcomes, this investigation will be thefirst to provide a framework needed to design programs to improve caregiver-provider health communication andmore effective caregiver oral health education and anticipatory guidance, and ultimately improve children’s oralhealth status.40
#65 Obesity-Induced Leptin Inhibits Streptococcus Mutans Growth But NotImmunostimulatory CytokinesR.J. TSENG, J.T. WRIGHT, and M.A. BECKDepartments of Pediatric Dentistry and NutritionOBJECTIVE: Research indicates obese children have decreased caries. Our objective was to determine if thisoccurred indirectly via leptin-induced modulation of cytokines important in host immune response, or directly, viainhibition of Streptococcus mutans (SM) growth. METHODS: Body mass index (BMI) was calculated for 80children aged 2-5 years to determine normal (CON) or overweight/obese (OW) weight status. Blood samples werecollected and assayed for serum leptin, tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6)concentrations. Decayed or filled surfaces (dfs) score and number of carious teeth were calculated. SM wascultured on agar plates with recombinant human leptin. Growth alteration was determined by calculating area ofzone of inhibition, and verified by spectrophotometrically measuring turbidity at 600nm. RESULTS: OW childrenhad significantly elevated serum leptin, fewer decayed teeth, and decreased dfs score compared to CON. TNFalphaand IL-6 expression were not significantly different in OW versus CON. Leptin inhibited growth of SM onagar plates in a dose-dependent fashion (0.1-10ng/ml). Turbidity of SM cultures incubated with leptin wasreduced by up to 50% (P
Page 3 and 4: Dear Colleagues:Thank you for your
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Page 34 and 35: #39 The Effects of Epidermal Growth
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Page 42 and 43: #55 Dentinogenesis Imperfecta: Rela
Page 44 and 45: #59 Comparison among CPP-ACP, Fluor
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