Pediatric Ventricular Assist Devices - University of Minnesota ...

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Survival in Children Bridged to Transplant100ECMO vs. VAD80All Others (n=1,442)VAD at Transplant (n=76)% Survival6040200ECMO at Transplant(n=102)Time ECMO VAD1 mo 80% 95%1 yr 73% 85%5 yr 66% 75%p= .0030 1 2 3 4 5 6 7 8 9 10Years After TransplantationBlume et al. Circ 2006; PHTS 1993-2004
Survival to Transplant: Status% Survival1009080706050403020100VAD (n=99)p (VAD vs Status 1) = .4Event: Death while waiting* (censored at Tx)Status 2 (n=612)Status 1 (n=1619)0 1 2 3 4 5 6 7 8 9 10 11 12Months after Listing (or VAD implant)Blume et al. Circ 2006; PHTS 1993-2004
Page 2 and 3: Disclosures• Berlin Heart Corpora
Page 4: Lillehei CW, Cohen M, Warden HE, et
Page 8 and 9: Pre 2004• ECMO• Adult Devices u
Page 10 and 11: ELSO Registry Survival by YearPedia
Page 12 and 13: Efficiency of ECMO as Bridge to Tra
Page 16 and 17: Post-Transplant Survival% Survival1
Page 18 and 19: Thoratec pVAD Ventricular AssistDev
Page 20 and 21: CHP Thoratec ExperiencePreimplantat
Page 22 and 23: % SurvivalSurvival to Transplant: A
Page 24: Tx Wait Times (mo) by Era, Status,
Page 27 and 28: Berlin Heart EXCOR ® PediatricSyst
Page 29 and 30: Berlin Heart (EXCOR)
Page 31 and 32: MicroMedDebakeyPediatricVAD
Page 33 and 34: Conventional Centrifugal PumpFlüge
Page 35 and 36: Levitronix: A New GenerationCentriM
Page 37 and 38: Filling the GapGapWeeksShort-term U
Page 40 and 41: NHLBI PCSP: Contract DevicesPediaFl
Page 42 and 43: Design EvolutionHeartQuest42
Page 44 and 45: 180The PF3 Has Flatter HQ Curvestha
Page 46 and 47: Blood Interactions withCardiovascul
Page 48 and 49: VAD Biocompatibility Issues• Hemo
Page 50 and 51: Pre-clinical Ovine Model• Healthy
Page 52 and 53: Serum ChemistriesPF2.117 daysPF2.13
Page 54 and 55: Children’s Hospital of Pittsburgh

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