The Production of Therapeutic Proteins in Plants: Apo AI and Insulin

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Plant Impurity Assays – HCP and OleosinRabbit anti-host cell protein antibodies were raised to thesoluble and oilbody fractions of safflower seed grindpreparations.Antibodies were supplemented with other polyclonals thatrecognized oilbody proteins for the ELISA.Limit of Detection =
Plant Impurity AssaysPhytate (IP 6 ) is the plant’s phosphate storage moleculeand requires phytase to release the phosphate.Phytate is an anti-nutrient – will bind important mineralsin the body such as calcium, zinc and iron.Phytate is assayed by digestion with phytase thenquantitation of phosphate using a commercial phosphateassay reagent (Bio-Mol Green) in a microplate format(620 nm).Limit of Detection =
Page 1 and 2: The Production of Therapeutic Prote
Page 3 and 4: SemBioSys OverviewLocation: Calgary
Page 5 and 6: SemBioSys’ TechnologyProof-of-Con
Page 7 and 8: Field Grown GMO SafflowerPlanting s
Page 9: Purification of OilbodiesThe Proces
Page 13 and 14: Product Impurity Assays - Fusion Pa
Page 15 and 16: Viral Load/Viral ClearanceRegulator
Page 17 and 18: InsulinPositioned to Meet the Growi
Page 19 and 20: Economics of Plant-Produced Insulin
Page 21 and 22: Insulin - Equivalence DataV8 Protea
Page 23 and 24: Insulin - Equivalence DataIGF-1 Rec
Page 25 and 26: Insulin Characterization: Clinical
Page 27 and 28: Apo AI Milano (SBS-2000)• FTO - S
Page 29 and 30: Functional Characterization of Puri
Page 31 and 32: Cholesterol Mobilization in vivoSBS
Page 33: Non-Pharma ProductsProducts and Com

The Production of Therapeutic Proteins in Plants: Apo AI and Insulin

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