The Production of Therapeutic Proteins in Plants: Apo AI and Insulin
The Production of Therapeutic Proteins in Plants: Apo AI and Insulin
The Production of Therapeutic Proteins in Plants: Apo AI and Insulin
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Insul<strong>in</strong> – Equivalence DataIGF-1 Receptor B<strong>in</strong>d<strong>in</strong>g Analysis <strong>of</strong> SBS-1000 DSIC50 Prediction Curves - IGF-1nM IGF10010IGF-1y = 27104x -2.3766R 2 = 0.98NIBSCy = 381217910928x -4.8196R 2 = 0.95USPy = 238270451661x -4.7054R 2 = 0.98SBS-1000y = 527721407540x -4.8927R 2 = 0.9610000100010010nM <strong>in</strong>sul<strong>in</strong>10 10 20 30 40 50 60 70 80 90 1001IGF-1 USP NIBSC SBS-1000% no lig<strong>and</strong> controlIC 50 value comparison (µU/ml)IGF-1SBSInsul<strong>in</strong>St<strong>and</strong>ardRatio toIGFRatio to Insul<strong>in</strong>St<strong>and</strong>ard2.48 2570 2471 1036 1.04 (NIBSC)2414 1.06 (USP)
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