The Production of Therapeutic Proteins in Plants: Apo AI and Insulin
The Production of Therapeutic Proteins in Plants: Apo AI and Insulin
The Production of Therapeutic Proteins in Plants: Apo AI and Insulin
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Insul<strong>in</strong> – Equivalence DataInsul<strong>in</strong> Receptor B<strong>in</strong>d<strong>in</strong>g Analysis <strong>of</strong> SBS-1000 DSIC50 Prediction Curves - Insul<strong>in</strong>300250USPy = 96415x -1.9211uU/ml <strong>in</strong>sul<strong>in</strong>20015010050SBS-1000y = 532058x -2.3245R 2 = 0.98R 2 = 0.96Humul<strong>in</strong>y = 201360x -2.1042R 2 = 0.98NIBSCy = 217904x -2.1133R 2 = 0.9800 10 20 30 40 50 60 70 80 90 100USP Humul<strong>in</strong> SBS-1000 NIBSC% no <strong>in</strong>sul<strong>in</strong> controlIC 50 value comparison (µU/ml)USPSBSInsul<strong>in</strong>NIBSCHRRatio toUSPRatio toNIBSCRatio toHR52.51 59.80 55.95 53.58 1.14 1.07 1.12