Download1 - EJUM - Universiti Malaya

54 Annals af Dentistry, University af Malaya, Val, 16 2009significant correlation between overexpression ofcyclin D I and underexpression of p27 with some,clinicopathological parameters which are knownindependent prognostic indicators. Thus, these resultssuggests that' over~xpression of cyclin D I andunderexpression of p27 may be used as prognosticmarkers for OSCC of buccal and alveolar mucosa.Recommendation: The findings of the presentstudy are considered preliminary as the samples usedwere small. A larger sample size with adequate data ofloco-recurrence and survival would give moredefinitive prognostic potential of cyclin D I and p27.Association between Mutans Streptococci,Lactobacilli and other risk factors withsevere early childhood cariesOr. Norita Abdul RahimDepartment of Children's Dentistry and OrthodonticsEarly childhood caries is a multifactorial disease' whichis most prevalent among childhood that warrants muchattention. The aim of this study was. to assess theassociation between mutans streptococci (MS),lactobacilli (LB) and other risk factors with severeearly childhood caries (S-ECC) in 5-year-old healthyMalay children. The objectives were (i) to investigatethe relationship between S-ECC with salivary MS andLB levei; (ii) to' investigate the relation;hip pet"'{een S-ECC with other risk factors such as .socioeconomicstatus, oral hygiene practices of child, feeding h~bits.. Of child and dietary habit of child and (iii) tounderstand·. the factors OT predicting S-ECC byassessing interrelationships between all the independentvariables and developing a logistic regression model.A convenient sample of 72 subjects, whereby, 35subjects were with S-ECC.(dmfs = 6) and 37 cariesfree, (dmfs = 0) as a control, were selected from 4preschools under Federal Islamic ne.p,artment, KualaLumpur. The study was cros~: sectional, case-c