FMRI Analysis Experiment Design

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Experiment Design in AFNI• Toy example: Design an experiment and check its efficiencyoWith TENT functions (modifying s3.Efficiency): TENT(0,12,7) (less efficient)Stimulus: stimAh[ 0] norm. std. dev. = 0.1676...h[ 6] norm. std. dev. = 0.1704Stimulus: stimBh[ 0] norm. std. dev. = 0.1694...h[ 6] norm. std. dev. = 0.1692Stimulus: stimCh[ 0] norm. std. dev. = 0.1666...h[ 6] norm. std. dev. = 0.1674General Linear Test: GLT #1LC[0] norm. std. dev. = 0.5862 (0.1677)General Linear Test: GLT #2LC[0] norm. std. dev. = 0.5826 (0.1765)General Linear Test: GLT #3LC[0] norm. std. dev. = 0.5952 (0.1680)Norm. Std. Dev. for21 regressorsNorm. Std. Dev. for3 contrasts: AUC orindividual basis function(stim[[0..6]])?
• Design search: Find an efficient designo TR = 2s, 300 TR’s, 3 stimulus types, 50 repetitions for each typeoScript @DesignSearch: ParametersExperiment Design in AFNI# TOGGLE btw the following 2 model parametersset model = GAM # toggle btw GAM and TENTset eff = SUM # toggle btw SUM and MAX# experiment parametersset ts = 300 # length of time seriesset stim = 3 # number of input stimuliset num_on = 50 # time points per stimulus# execution parametersset iterations = 100# number of iterationsset seed = 248390 # initial random seedset outdir = Results # move output to this directoryset TR = 2 # TR Length in secondsset ignore = 4 # number of TRs ignoredset show = 10 # number of designs shown# Directories to store output filesset outdir = ${outdir}_${model}_$effset LCfile = $outdir/LCif ("$model" == "TENT") set model = ${model}'(0,12,7)'
Page 7: • Classical HRFooooIntuitive Thin
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Page 24 and 25: Find an efficient designo Efficient
Page 26: • Dealing with low frequenciesooo

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