The MISST structure is based on the Collector-Distributor 36 of the I-10 Santa Monica Freewaywhich was damaged during the 17 January 1994 Northridge Earthquake. To utilize currentNEES experimental facilities <strong>and</strong> <strong>for</strong> simplification, an idealization of the original structure wasemployed (Figure 1). As shown, the bridge is assumed to have three piers of varying height <strong>and</strong>is supplemented with soil models to include the effects of soil-structure interaction. The SantaMonica strong motion record was used exclusively throughout this investigation.As subsequently detailed, the project utilized the large-scale NEES facilities of both UIUC <strong>and</strong>Lehigh University, in addition to advanced geotechnical modeling at RPI, to fully model thebehavior of the MISST structure. In an ef<strong>for</strong>t to manage the broad <strong>and</strong> complex scope of theproject, testing was approached incrementally. As such, several subtasks were developed <strong>and</strong> arein various stages of completion. A description of each follows.27.215 m 23.700 m 32.260 m30.795 m6.085 m6.575 m 6.085 mFigure 1. MISST test structureSingle pier component testTo reconstruct <strong>and</strong> verify the failure mode observed in the freeway structure, a single large-scalepier specimen was constructed <strong>and</strong> tested at UIUC. Figure 2 provides a comparison between theobserved behaviors. As shown, the laboratory test successfully reproduced the shear failureobserved in the field.Distributed analytical simulationa. Field response b. Laboratory responseFigure 2. Observed pier behaviorFollowing the component test, communication through NEESgrid between the various sites wasestablished <strong>and</strong> validated through a fully analytical distributed simulation. The substructure
GINA_WR_2006.qxp:GINA_WR_2006.qxp 7/20/07 4:11 PM Page *1Global Strategy <strong>for</strong> Asthma Management <strong>and</strong> Prevention 2006GINA EXECUTIVE COMMITTEE*Paul O'Byrne, MD, ChairMcMaster UniversityHamilton, Ontario, CanadaEric D. Bateman, MDUniversity of Cape TownCape Town, South Africa.Jean Bousquet, MD, PhDMontpellier University <strong>and</strong> INSERMMontpellier, FranceTim Clark, MDNational Heart <strong>and</strong> Lung InstituteLondon United KingdomKen Ohta. MD, PhDTeikyo University School of MedicineTokyo, JapanPierluigi Paggiaro, MDUniversity of PisaPisa, ItalySoren Erik Pedersen, MDKolding HospitalKolding, DenmarkManuel Soto-Quiroz, MDHospital Nacional de NiñosSan José, Costa RicaRaj B Singh MDApollo HospitalChennai, IndiaWan-Cheng Tan, MDSt Paul's Hospital,Vancouver, BC, CanadaGINA SCIENCE COMMITTEE*Eric D. Bateman, MD, ChairUniversity of Cape TownCape Town, South AfricaPeter J. Barnes, MDNational Heart <strong>and</strong> Lung InstituteLondon, UKJean Bousquet, MD, PhDMontpellier University <strong>and</strong> INSERMMontpellier, FranceJeffrey M. Drazen, MDHarvard Medical SchoolBoston, Massachusetts, USAMark FitzGerald, MDUniversity of British ColumbiaVancouver, BC, CanadaPeter Gibson, MDJohn Hunter HospitalNSW, New Castle, AustraliaPaul O'Byrne, MDMcMaster UniversityHamilton, Ontario, CanadaKen Ohta. MD, PhDTeikyo University School of MedicineTokyo, JapanSoren Erik Pedersen, MDKolding HospitalKolding, DenmarkEmilio Pizzichini. MDUniversidade Federal de Santa CatarinaFlorianópolis, SC, BrazilSean D. Sullivan, PhDUniversity of WashingtonSeattle, Washington, USASally E. Wenzel, MDNational Jewish Medical/Research CenterDenver, Colorado, USAHeather J. Zar, MDUniversity of Cape TownCape Town, South AfricaREVIEWERSLouis P. Boulet, MDHopital LavalQuebec, QC, CanadaWilliam W. Busse, MDUniversity of WisconsinMadison, Wisconsin USANeil Barnes, MDThe London Chest Hospital, Barts <strong>and</strong> theLondon NHS TrustLondon, United KingdomYoshinosuke Fukuchi, MD, PhDPresident, Asian Pacific Society of RespirologyTokyo, JapanJohn E. Heffner, MDPresident, American Thoracic SocietyProvidence Portl<strong>and</strong> Medical CenterPortl<strong>and</strong>, Oregon USADr. Mark LevyKenton Bridge Medical CentreKenton, United KingdomCarlos M. Luna, MDPresident, ALATUniversity of Buenos AiresBuenos Aires, ArgentinaDr. Helen K. ReddelWoolcock Institute of Medical ResearchCamperdown, New South Wales, AustraliaStanley Szefler, MDNational Jewish Medical & Research CenterDenver, Colorado USAGINA Assembly Members Who SubmittedCommentsProfessor Nguygen Nang AnBachmai University HospitalHanoi, VietnamProfessor Richard BeasleyMedical Research Institute New Zeal<strong>and</strong>Wellington, New Zeal<strong>and</strong>Yu-Zi Chen, MDChildren's Hospital of The Capital Institute ofPediatricsBeijing, ChinaLadislav Chovan, MD, PhDPresident, Slovak Pneumological <strong>and</strong>Phthisiological SocietyBratislava, Slovak RepublicMotohiro Ebisawa, MD, PhDNational Sagamihara Hospital/Clinical Research Center <strong>for</strong> AllergologyKanagawa, JapanProfessor Amiran GamkrelidzeTbilisi, GeorgiaDr. Michiko HaidaHanzomon Hospital,Chiyoda-ku, Tokyo, JapanDr. Carlos Adrian JiménezSan Luis Potosí, MéxicoSow-Hsong Kuo, MDNational Taiwan University HospitalTaipei, TaiwanEva Mantzouranis, MDUniversity HospitalHeraklion, Crete, GreeceDr. Yousser MohammadTishreen University School of MedicineLattakia, SyriaHugo E. Neffen, MDChildren HospitalSanta Fe, ArgentinaEwa Nizankowska-Mogilnicka, MDUniversity School of MedicineKrakow, Pol<strong>and</strong>Afshin Parsikia, MD, MPHAsthma <strong>and</strong> Allergy ProgramIranJose Eduardo Rosado Pinto, MDHospital Dona EstefaniaLisboa, PortugalJoaquín Sastre, MDUniversidad Autonoma de MadridMadrid, SpainDr. Jeana Rodica RaduN. Malaxa HospitalBucharest, RomaniaMostafizur Rahman, MDDirector <strong>and</strong> Head, NIDCHDhaka, BangladeshVaclav Spicak, MDCzech Initiative <strong>for</strong> AsthmaPrague, Czech RepublicG.W. Wong, MDChinese University of Hong KongHong Kong, ChinaGINA ProgramSuzanne S. Hurd, PhDScientific DirectorSarah DeWeerdtMedical Editor*Disclosures <strong>for</strong> members of GINA Executive <strong>and</strong> Science Committees can be found at:http://www.gin<strong>asthma</strong>.com/Committees.asp?l1=7&l2=2i