Mehdi Gasmi, PhD

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Detailed presentation of Genethon’s rAAV-BAC systemDr. Otto W. MertenINV069Sat. 27 Oct. 16h30-Session 4B“GMP and bioprocess development for GT vectors”

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Further improvementsbreakthroughtechnologyTour Montparnasse1000 L Bulk~1,25x10 15166 Wks (>3 y)Bioreactor 200L200 L Bulk~ 2 E x10 156 WksBioreactor 20L20 L Bulk~ 2x10 156 Wks

Detailed presentation of Genethon’s rAAV-BAC systemDr. Otto W. MertenINV069Sat. 27 Oct. 16h30-Session 4B“GMP and bioprocess development for GT vectors”

Page 1 and 2: Improvements towards the industrial
Page 3 and 4: AAV vectors in the clinic‣~30% pr
Page 5 and 6: Transfection for rAAV production at
Page 7 and 8: Transfection in suspension: lack of
Page 9 and 10: Baculovirus Technology‣rAAV produ
Page 11 and 12: AAV -Bac systemSf9 MCB/WCBAmplifica
Page 13 and 14: vg titer (vg/mL)rAAV-Bac: YieldsRes
Page 15: Comparison rAAV transfection vs. rA

Mehdi Gasmi, PhD

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