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MDS Details14Input Data: 100K sequences from well-characterizedprokaryotic COGs.Proximity measure: sequence alignment scoresScores calculated using Needleman-WunschScores “sqrt 4D” transformed and fed into MDSAnalytic form for transformation to 4D ijndecreases dimension n > 1; increases n < 1“sqrt 4D” reduced dimension of distance data from244 for ij to14 for f( ij )Hence more uniform coverage of Euclidean spaceVisualizing PSUECMLS 2012
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