(Wessex) Technology Assessment ChromoQuant™ (version 1)

1.4 were defined as normal (a ratio of 1.5 was considered acceptable if the alleles were separated bymore than 24bp), ratios of >1.8 or 0.8 or < 1.4Trisomic (3 alleles)Expected allele ratio is 1:1:14bp4bpTrisomic (3 alleles)Expected allele ratio is 2:1Result classified as trisomic if alleleratio is> 1.8 or < 0.654bpFigure 2: Interpretation of Data. Allele ratios can be uninformative, normal (2 alleles with a 1:1 ratio), trisomic (3alleles) or trisomic (3 alleles with a 2:1 ratio)5