dose-volume

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PAUL SCHERRER INSTITUTPlanning criteriaProblems in strictly defining planning criteriaNaso-pharynx comparison results (2 from 6)Results of biological modelingPlan 1Plan 2TCP(CTV)60%60%NTCP(BS)NTCP(LOPN)0% 0%1% 8%But….Coverage of PTVin region of opticnerve deliberatelycompromised byplan 1, but not byplan 2.Plan 1Plan 2A problem of conflicting criteria. Sparing of optic nerve canonly be achieved by compromising defined safety margin.SGSMP/SRO Physics Lectures 2007PD Dr Tony LomaxTreatment plan evaluation
PAUL SCHERRER INSTITUTPlanning criteria4. Conflict resolutionIn many cases, it may not be possible to satisfy both targetcoverage and normal tissue constraints with any one plan.In this case, additional constraints relating to how suchconflicts should be dealt with are required.Examples….1. Target coverage has priority (plan 2)Plan 12. Normal tissues have priority (plan 1)3. Compromise solution based onweighting factors for different VOIs(e.g. using biological models?)Plan 24. ‘Optimised’ solution.SGSMP/SRO Physics Lectures 2007PD Dr Tony LomaxTreatment plan evaluation
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