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PAUL SCHERRER INSTITUTOptimisation criteriaWhat is optimal? An exampleRight globeRelative <strong>volume</strong>(%)IMPTIMXT 1Single <strong>dose</strong> weightingfunctionOptimisation makesno attempt to reduce<strong>dose</strong>s below constraint(zero weight)Dose (%)What happens when we use a <strong>dose</strong>-<strong>volume</strong> constraint toattempt to match IMXT DVH to IMPT (nominal) DVH?SGSMP/SRO Physics Lectures 2007PD Dr Tony LomaxTreatment plan evaluation

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