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PAUL SCHERRER INSTITUTBiological scoring.Reasons to be cautious.2. Normalising to low NTCP values.Consider a set of <strong>dose</strong>-response curves for the rectum with the estimatedNTCPs for 60 and 80 Gy varied by +/- 5%Variation in NTCP5 dependingon response curve usedNTCP (%)Dose (cGy)55 - 68 GyIf TCP curve is well separatedfrom NTCP curve, such anuncertainty can result in muchlarger uncertainties in TCPestimationTCP 20 - 80 % in this case!SGSMP/SRO Physics Lectures 2007PD Dr Tony LomaxTreatment plan evaluation

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