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The School of Public Health, Degrees, Special Programs PUBLIC ...

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254. Occupational and Environmental<br />

Epidemiology. (3) Two one-and-one-halfhour<br />

lectures per week. Prerequisites: 250A.<br />

Epidemiological methods for designing,<br />

conducting, and interpreting epidemiological<br />

studies <strong>of</strong> persons occupationally or environmentally<br />

exposed to chemical and physical<br />

agents. A. Smith (Sp)<br />

255A. Social Epidemiology. (3) Three hours<br />

<strong>of</strong> lecture/discussion per week. Prerequisites:<br />

Consent <strong>of</strong> instructor. 142, 145, and<br />

250A-250B recommended. This course is<br />

designed to introduce students to the field<br />

<strong>of</strong> social epidemiology and its role in understanding<br />

the social determinants <strong>of</strong> population<br />

health and health disparities. This course will<br />

provide a systematic and selected overview<br />

<strong>of</strong> literature in the field covering the history<br />

and development <strong>of</strong> the field <strong>of</strong> social epidemiology,<br />

theoretical perspectives, major<br />

topical areas, conceptual approaches, and current<br />

controversies related to theory, research<br />

methods, and research findings. Three<br />

principles will be emphasized throughout<br />

the course: (1) the ecological model, (2) the<br />

lifecourse approach, and (3) causality. <strong>The</strong>se<br />

principles will provide a framework for the<br />

critical analysis <strong>of</strong> scholarly journal articles<br />

and the synthesis <strong>of</strong> information across content<br />

areas. This is a breadth course intended<br />

to provide an overview <strong>of</strong> the field <strong>of</strong> social<br />

epidemiology; and expose students to relevant<br />

areas <strong>of</strong> study. This is not a Methods<br />

course. Nuru-Jeter (Sp)<br />

255C. Mental <strong>Health</strong> and Psychopathology.<br />

(3) Three hours <strong>of</strong> seminar per week. Prerequisites:<br />

Open only to graduate students. This<br />

graduate seminar is designed to provide<br />

an understanding <strong>of</strong> the complex (and <strong>of</strong>ten<br />

interactive) individual and environmental<br />

conditions that increase the risk <strong>of</strong> psychopathology<br />

in individual across the life span.<br />

We will start by learning about general<br />

concepts important to and understanding <strong>of</strong><br />

psychopathology and prevention <strong>of</strong> psychopathology,<br />

including the “biopsychosocial<br />

model,” “psychological resilience,” and different<br />

levels <strong>of</strong> preventive interventions. For<br />

each different area <strong>of</strong> psychopathology, we<br />

will consider: (1) the core features <strong>of</strong> the disorder;<br />

(2) key theory and empirical evidence<br />

regarding etiology and course, with a particular<br />

emphasis on understanding the range <strong>of</strong><br />

risk and protective factors on the individual,<br />

family, and community level; and (3) the<br />

implications <strong>of</strong> etiological understanding for<br />

public health efforts to prevent the particular<br />

disorder. Ozer (F)<br />

255D. Methods in Social Epidemiology. (2)<br />

This course is designed to review, evaluate<br />

and apply methods currently used in the field<br />

<strong>of</strong> social epidemiology. <strong>The</strong> course aims to<br />

teach approaches to forming clear research<br />

questions, and selecting the best method(s)<br />

to answer the questions posed. Initially we<br />

will discuss approaches to defining clear and<br />

specific research questions. We will then discuss<br />

recent controversies around the meaning<br />

<strong>of</strong> questions posed in social epidemiology,<br />

and the ability <strong>of</strong> currently used methods to<br />

answer questions in social epidemiology.<br />

Finally, we will review, evaluate and apply<br />

a range <strong>of</strong> different methods that are or<br />

could be used to answer questions in social<br />

epidemiology, again emphasizing the types<br />

<strong>of</strong> questions answered by these methods,<br />

and their ability to address the challenges to<br />

effectively answering questions in social epidemiology.<br />

<strong>The</strong>re will be a mixture <strong>of</strong> discussion<br />

and lecture depending on the topic, with<br />

student participation and questions strongly<br />

encouraged. Ahern, Hubbard (Sp)<br />

255E. Structural Inequalities and<br />

Reproductive <strong>Health</strong>. (2) This course will<br />

address the role that structural inequalities<br />

assume in shaping reproductive health disparities.<br />

We will examine relevant epidemiological<br />

research, review and critique public<br />

health interventions, and discuss how research<br />

in this area can inform policy. <strong>The</strong> course<br />

will be organized around three modules,<br />

each linked to reproductive health: poverty;<br />

gender-based violence; and migration. Within<br />

each module, students will examine measurement,<br />

research design and ethical challenges.<br />

Krishnan, Minnis, Dunbar (Sp)<br />

256. Molecular and Genetic Epidemiology.<br />

(4) One two-hour lecture and one one-hour<br />

labo-ratory per week. This course will cover<br />

designs and methods for genetic epidemiology<br />

studies <strong>of</strong> unrelated individuals and families.<br />

Concepts in population genetics relevant<br />

to understanding approaches in genetic epidemiology<br />

are introduced, including Hardy-<br />

Weinberg equilibrium and linkage disequilibrium,<br />

genetic risk models, admixture, and<br />

methods for haplotype estimation. Evaluation<br />

<strong>of</strong> single and multiple loci in the context <strong>of</strong><br />

direct and indirect associations with human<br />

disease is also addressed. Linkage analysis<br />

to identify disease genes in different family<br />

structures will be introduced. Methods for<br />

gene-gene and gene-environment interaction<br />

assessment are also presented. <strong>The</strong> lecture<br />

material will be supplemented with examples<br />

using real and simulated data and currently<br />

available s<strong>of</strong>tware in a computer laboratory<br />

setting. Molecular epidemiology and the use<br />

<strong>of</strong> biological markers will be explored with<br />

the goal <strong>of</strong> illustrating both the power and<br />

limitations <strong>of</strong> biomarkers currently available for<br />

epidemiological research. Laboratory work and<br />

Internet demonstrations will provide hands-on<br />

experience with modern methods <strong>of</strong> molecular<br />

epidemiology. Holland (F)<br />

257. Outbreak Investigation. (1,3) One onehour<br />

seminar per week and field work outside<br />

class time. Prerequisites: Consent <strong>of</strong> instructor.<br />

This course will teach students why and<br />

how clusters <strong>of</strong> illnesses/epidemics are investigated.<br />

Methods and approaches required for<br />

such investigations will be discussed in detail,<br />

using published articles from the scientific<br />

literature to provide examples. Field work, to<br />

be conducted outside regular class hours, will<br />

involve the investigation <strong>of</strong> actual outbreaks<br />

and clusters in conjunction with nearby county<br />

health departments and under the supervision<br />

<strong>of</strong> the instructor. Students may opt to take the<br />

seminar component without the field work for<br />

one unit. Reingold (F, Sp)<br />

257A. Disaster Epidemiology: Methods and<br />

Applications. (2) Two hours <strong>of</strong> lecture per<br />

week. This course is an introduction to disaster<br />

epidemiology. Epidemiologists play an<br />

important role in assessing the health effects<br />

<strong>of</strong> natural and man-made disasters and in<br />

identifying the factors that contribute to these<br />

effects. <strong>The</strong> emphasis <strong>of</strong> this course will be<br />

on the application <strong>of</strong> epidemiologic methods<br />

to the study <strong>of</strong> the public health consequences<br />

<strong>of</strong> disasters with the purpose <strong>of</strong> identifying<br />

lessons learned from previous disasters,<br />

highlighting key skills that an epidemiologist<br />

would need to be a part <strong>of</strong> a response, identifying<br />

methodological issues for future work.<br />

Enanoria, Aragon (Sp)<br />

39

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