Katherine Anderson, ND FABNO National Director Naturopathic ...

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40% of people with cancer have radiation as part of their treatment plan. 65-‐100% of patients receiving radiation experience CRF (10) . Radiation can cause cumulative fatigue and this can occur regardless of treatment site. CRF usually lasts from 3-‐4 weeks after treatment stops, but can continue for up to 2-‐3 months or sometimes indefinitely.
Questionnaires and blood samples from 15 prostate cancer patients receiving EBRT at 7 time points. Human Mitochondria RT Profiler PCR Array was used to identify differential regulation of genes involved in mitochondrial biogenesis and function. 11 genes related to mitochondrial function and structure were differentially expressed. Of these 11 genes, 3 were up-‐regulated, and 8 were down-‐regulated. 8 genes (AIFM2, BCL2, FIS1, IMMP2L, MSTO1, SLC25A23, SLC25A37, SLC25A4) were associated with changes in fatigue scores. Suggests 8 mitochondrial function genes were associated with fatigue in prostate cancer patients during EBRT. These findings identify possible pathways and early biomarkers for targeting novel interventions for CRF.
Page 1 and 2: Katherine Anderson, ND FABNO Nat
Page 3 and 4: “Although the world is full
Page 5 and 6: National Comprehensive Cancer Net
Page 7 and 8: CRF is more than regular tired
Page 9 and 10: Uni-‐dimensional tools: Measu
Page 11 and 12: Reasons for patients to under-
Page 13 and 14: 1. Conventional Cancer Therapies
Page 15 and 16: CRF can have serious implicatio
Page 17: Frequency of side effects experienc
Page 21 and 22: Treatments that act on processe
Page 24 and 25: Often transfusion given when Hb
Page 26 and 27: Gastrointestinal Dysfunction Hepa
Page 28 and 29: Loss of appetite or insufficien
Page 30 and 31: Chronic severe pain increases f
Page 32 and 33: The impact of cancer-related fatigu
Page 34 and 35: Problems range from hypersomnia
Page 36 and 37: 3. Proton pump inhibitors Patie
Page 38 and 39: Lack of physical activity tir
Page 40 and 41: “the combination of the best
Page 42 and 43: 1. Lifestyle Modifications 2. Sl
Page 44 and 45: Sleep hygiene, including: Avoida
Page 46 and 47: Exercise has the best evidence
Page 48 and 49: Studies have confirmed it is c
Page 50 and 51: RCT w/ 78 breast cancer surviv
Page 52 and 53: RCT, 162 patients; Qigong deliv
Page 54 and 55: Adequate vitamins. multivitamin
Page 56 and 57: © 2008 Rising Tide, Kft. 56
Page 58 and 59: RCT; 47 fatigued patients with
Page 60 and 61: Several meta-‐analyses evalua
Page 62 and 63: Study investigated relationship
Page 64 and 65: Rhodiola (46) . Methodological f
Page 66 and 67: Randomly assigned 152 fatigued
Page 68 and 69:
Mayo clinic conducted a prospec
Page 70:
New treatment options will like
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Katherine Anderson, ND FABNO National Director Naturopathic ...

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