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Katherine Anderson, ND FABNO National Director Naturopathic ...

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Solid tumor patients with fatigue have higher serum markers of immune inflammatory activity (IL-­‐6, IL-­‐1 receptor antagonist, C-­‐reactive protein, neopterin, soluble TNF receptor II) (20) . Persistent fatigue may be caused by chronic inflammatory process involving the T-­‐cell compartment. Changes in cortisol regulation. Very high and very low levels of serotonin in the brain are associated with CRF (21) .

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