May 2008 - bcps

More documents

Recommendations

Info

Radioiodine (131i) Therapy for Thyrotoxicosis Patients and their OutcomeSK Biswas et al13. Hamburger JI, Hamburger SW.Diagnosis and managementof large toxic multinodular goiters.J Nucl Med1985;26:888-892.14. Nygaard B, Faber J, Hegedus L. Acute changes in thyroidvolume and function following 131I therapy ofmultinodular goiter. Clin Endocrinol 1994; 41: 715-718.15. Falk S. In: Thyroid disease: Endocrinology, Surgery,Nuclear Medicine, Radiotherapy. Falk S ed. New York,Raven press 1990:251.16. Beierwaltes WH. The treatment of hyperthyroidism with131I .Semin Nucl Med 1978; 8: 95-103.17. Clarke SEM. Throid disease.In: Maisey MN,Britton KE,Coiller BD eds. Clinical Nuclear Medicine, 3rd ed.Chapmanand Hall Medical 1998: pp 12.18. Datz FL.Endocrine system imaging.Handbook of NuclearMedicine ,2nd ed, Mosby 1993:pp 17-18.19. Chapman EM. Treatment of hyperthyroidism withradioactive iodine.In: Blahd WH ed. Nuclear Medicine ,2nded.New York,Blakistin 1971:730.20. Alevizaki CC, Alevizaki-Harhalaki MC, IkkosDG.Radioiodine-131-treatment of thyrotoxicosis:doserequired for and some factors affecting the early inductionhyperthyroidism.Eur J Nucl Med 1985;10: 450-454.21. Glennon JA,Gordon ES, Sawin CT. Hyperthyroidism afterlow dose 131I treatment of hyperthyroidism .Ann InternMed 1976:721-723.22. Goolden AWG, Steward JSW. Long term results fromgraded low dose radioactive iodine therapy forthyrotoxicosis.Clin Endocrinol 1986; 24: 217-222.23. Beierwalts WH. In: Thyroid disease: Endocrinology,Surgery, Nuclear Medicine, and Radiotherapy. Falk S ed.New York, Raven press 1990: pp 237.24. Hagen GA,Oulette RP,Chapman EM. Comparison of highand low dosage levels of 131I in the treatment ofthyrotoxicosis.N Engl J Med 1967; 177:559-562.25. Ross DS, Daniles GH, De Stefano P, Maloof F,RidgwayEC.Use of adjunctive potassium iodine after radioactiveiodine (131I) treatment of Garaves’ hyperthyroidism. J ClinEndocrinol Metab 1983; 576: 250-253.26. Hussain FA, Nisa L, Hoque M, Jehan AH. Teenagehyperthyroidism and radioiodine therapy. World Journal ofNuclear Medicine 2007; 6 (Vol. supplement1) (abstract)78
Journal of Bangladesh College of Physicians and SurgeonsVol. 26, No. 2, May 2008Co-relation between Sepsis Score and Blood CultureReport in Neonatal SepticaemiaS AFROZA a , F BEGUM bSummary:Objective: To determine the clinical profile and to corelatethe sepsis score with blood culture reports inneonatal septicaemia. Methods: Over a period of 6 months(1st week of June to 1st week of December'2005) 50consecutive newborns with suspected septicaemia wereenrolled for the study. It was a prospective study andsepticaemia was suspected on the basis of clinicalpresentation like reluctance to feed, lethargy, fever,abdominal distension etc. Sepsis scoring was done for allof them immediately after enrollment into the study.Investigations like CBC, CRP and blood culture were sentfor all the enrolled cases. Then the sepsis scores werecompared with their blood culture reports to find out anycorrelation between them. The data analysis was done bySPSS software. Results: Among the 50 studied babies 31were male and rest were female. Most of them weredelivered by vaginal delivery (74%) but no significantdifference was observed among home and institutionaldelivery. During delivery 24 babies experienced someIntroductionNeonatal sepsis is one of the major health problemsthroughout the world. Infections are a frequent andimportant cause of morbidity and mortality innewborn period’. As many as 2% of foetus areinfected in utero and upto 10% of infants are infectedin first month of life’. Data suggests that among fourmain causes of neonatal death, infection topped thelist 2 . Every year an estimated 30 million newbornsacquire infection and 1-2 million of these die 3 .a. Prof. Syeda Afroza, (Appear in the article: S Afroza/Afroza Sas applicable for the journal) MBBS, FCPS, Paed, DMEd(UK), MMEd (UK), Clinical Fellow of Neonatology (UK),FRCP (Edin), Professor (Paediatrics), Curriculum Developmentand Evaluation Centre for Medical Education, Mohakhali,Dhaka-1212.b. Dr. Feroza Begum, MBBS, Asstt. Registrar, Department ofPaediatrics, Institute of Child and Mother Health, MatuailDhaka-1362Address for correspondence: Prof. Syeda Afroza, (Appear in thearticle: S Afroza/Afroza S as applicable for the journal) MBBS,FCPS, Paed, DMEd (UK), MMEd (UK), Clinical Fellow ofNeonatology (UK), FRCP (Edin), Professor (Paediatrics),Curriculum Development and Evaluation Centre for MedicalEducation, Mohakhali, Dhaka-1212.Received: 9 July, 2006 Accepted: 7 March, 2007problems of which 83.3% had perinatal asphyxia. About59% of the studied babies were not exclusively breastfed.Majority of them (62%) presented with reluctance to feedand 54% were preterm low birth weight. Fever andrespiratory distress were present in 19 (38%) and 18(36%) cases respectively. Forty two percent studied babieshad positive sepsis score 5 and above. Regardingcorrelation of blood culture and sepsis score , 70% culturepositive cases had sepsis score 5 and above whereas 35%of culture negative cases had the same score. Sensitivityand specificity of sepsis score was 70 and 65 respectivelywith CI interval 95%. Conclusion: Sepsis score can beconsidered as an useful tool in the diagnosis of neonatalsepticaemia specially where there is lack of investigationalfacilities. Before using this tool further evaluation isneeded involving large sample size.Key words: Neonatal septicaemia, sepsis score, bloodculture.(J Bangladesh Coll Phys Surg 2008; 26: 79-82)Neonatal sepsis (also called septicaemia) is defined asa clinical syndrome characterized by signs of systemicinfection and documented by a positive blood culturein the first four weeks of life 1,4-7 . Newborns of wholeworld specially those of third world countries are mostvulnerable group for this illness. It is crucial to protectthe newborns from infection as far as it is possible. Ina poor country like ours, it is the responsibility ofpaediatricians (besides neonatologists) to address thisserious neonatal health problems.In developing countries the organisms causingneonatal sepsis and meningitis are different. ABangladeshi study showed that there is considerablechange in bacteriae causing neonatal sepsis andmeningitis in 5 years period.(1998-2003) 8 . In thatstudy Klebsiella pneumoniae remained the leadingpathogen comprising 23% in 1998 and 23.4% in 2003in causing neonatal sepsis. S aureus was 17% and 6%respectively and Acinatobacter 6.7% and 20.4%respectively.A number of prepartum and intrapartum obstetriccomplications are associated with increased79-82
Page 2 and 3: Journal of Bangladesh College ofPhy
Page 4 and 5: Introduction:The introduction will
Page 6 and 7: JOURNAL OF BANGLADESH COLLEGE OFPHY
Page 8 and 9: Journal of Bangladesh College of Ph
Page 10 and 11: ORIGINAL ARTICLESSerum Apoprotein (
Page 12 and 13: Serum Apoprotein ( ApoA1 and ApoB)
Page 14 and 15: Serum Apoprotein ( ApoA1 and ApoB)
Page 16 and 17: Problems and Immediate Outcome of I
Page 22 and 23: Radioiodine (131i) Therapy for Thyr
Page 24 and 25: Radioiodine (131i) Therapy for Thyr
Page 28 and 29: Co-relation between Sepsis Score an
Page 30 and 31: Co-relation between Sepsis Score an
Page 32 and 33: Juvenile Idiopathic Arthritis Essen
Page 40 and 41: Approach to Subclinical Thyroid Dis
Page 46 and 47: Gonadoblastoma: Primary Amenorrhoea
Page 48 and 49: Journal of Bangladesh College of Ph
Page 50 and 51: Henoch-Schonlein Purpura in an Elde
Page 52 and 53: Malignant Melanoma of the Vagina -
Page 54 and 55: COLLEGE NEWS(J Bangladesh Coll Phys
Page 56 and 57: College NewsRoll No. Name of candid
Page 58 and 59: College NewsContinuing Professional

May 2008 - bcps

Create successful ePaper yourself

Delete template?

Save as template?