RIBOFLAVIN

Documentazione distribuita da A.I.CHE. - Associazione Italiana CHEratoconici ONLUS (www.assocheratocono.org)• The clinical evidence that diabeticpatients are rarely affected bykeratoconus supported these studies.In affected patients the natural cross-linking effect of glucose produces anincrease of corneal resistance(Maillard’s reaction).• An increase in corneal resistance, dueto natural collagen glycosilation,occurs also with ageing.