Pharmacology

More documents

Recommendations

Info

Dose Response Relationships• Potency– Absolute amount of of drug required to to producean effect– More potent drug is is the one that requires lowerdose to to cause same effect
PotencyABEffectTherapeuticEffectWhy?A!DoseWhich drug is more potent?
Page 1 and 2: PharmacologyPharmacokineticsPharmac
Page 3 and 4: Pharmacokinetic Processes“LADME
Page 5 and 6: Absorption• Movement from adminis
Page 7 and 8: Membranes and AbsorptionSmall,uncha
Page 9: 4. System 3. 2. 1. System Stress Sy
Page 12 and 13: A real live, actual clinicalquestio
Page 14 and 15: Moral of the story...Acidic drugs a
Page 16 and 17: Distribution• Rate of perfusion
Page 18 and 19: Blood-Brain Brain BarrierThe blood
Page 20 and 21: Hepatic ‘First-Pass’Metabolism
Page 22 and 23: Active Tubular TransportProbenecid
Page 24 and 25: How will this affect phenobarbitalr
Page 26 and 27: Biological Half-life life (t 1/2 )
Page 28 and 29: Administration Routes• Intravenou
Page 30 and 31: Pharmacodynamics• The biochemical
Page 32 and 33: Receptor InteractionsLock and key m
Page 34 and 35: Receptor InteractionsCompetitiveInh
Page 36 and 37: Non-receptor Mechanisms• Actions
Page 38 and 39: Non-receptor Mechanisms• Changing
Page 40 and 41: Non-receptor Mechanisms• Anti-met
Page 42 and 43: Time Response RelationshipsMaximal
Page 46 and 47: Dose Response Relationships• Thre
Page 48 and 49: Dose Response Relationships• Load
Page 50 and 51: Therapeutic IndexWhy don’t we use
Page 52 and 53: Factors Altering DrugResponses• E
Page 54 and 55: Influencing factors• Genetic effe
Page 56 and 57: Geriatric Patients• Chronic disea
Page 58 and 59: Web Resources• Merk Manual: Facto

Pharmacology

Create successful ePaper yourself

Delete template?

Save as template?