Granulation - Rottendorf Pharma GmbH
Granulation - Rottendorf Pharma GmbH
Granulation - Rottendorf Pharma GmbH
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Schmelzextrusion | Hot Melt Extrusion | Extrusion par fusion<br />
PHARMACEUTICAL MELT EXTRUSION<br />
Melt extrusion is understood as a continuous or<br />
discontinuous pressing of a strand from mouldable<br />
material.<br />
By using thermoplastic materials such as<br />
EUDRAGIT ® -copolymers melt extrusion leads to<br />
significant advantages for certain formulations and<br />
improves the availability of APIs.<br />
� Enhancement of poorly soluble APIs<br />
� Sustained release<br />
� Controlled release<br />
� Taste masking<br />
THE MELT EXTRUSION PROCESS<br />
Dosing<br />
www.evonik.com<br />
Weighing<br />
Extrusion<br />
Mixing<br />
Output forms of this specific technology:<br />
� Granules<br />
� Microspheres<br />
� Powders<br />
� Sheets<br />
� Films<br />
Melting Homogenizing +<br />
Discharge<br />
Downstreaming<br />
Cooling<br />
Granulating
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