06.09.2015 Views

NGF trkA and p75

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acclimate<br />

2 wks<br />

One day<br />

prior to<br />

training,<br />

darken hair<br />

dye on the<br />

top of head<br />

<strong>and</strong> neck<br />

Hidden platform<br />

3 trial/days<br />

1 2 3 4 5 6 7 8 9 10<br />

Hidden platform<br />

2 trials/days<br />

followed by a probe trial.<br />

3 days later<br />

terminally<br />

anesthetized<br />

12 15<br />

Two days later<br />

tested in a cued<br />

version<br />

Water maze<br />

- circular pool 1.5 m in diameter with a<br />

wall 30 cm high in a well-lit lit room<br />

- water filled within 10 cm of the rim<br />

with 26 °C C water colored with nontoxic<br />

white paint (Createx)<br />

- round escape platform (12 cm<br />

diameter) was located in a constant<br />

position in the "center" of one of the four<br />

imaginary quadrants of the pool.<br />

Behavioral training between 1300 <strong>and</strong> 1700 h.<br />

25<br />

26<br />

Ø 1.5 m<br />

Ø 1.5 m<br />

30 cm<br />

30 cm<br />

20 cm<br />

27<br />

ø12 cm<br />

Beneath<br />

water 2cm<br />

28<br />

2.start<br />

1.start<br />

3.start<br />

29<br />

30

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