La néoangiogenèse tumorale
VEGF - FMC de Tours
VEGF - FMC de Tours
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Le switch angiogénique<br />
INHIBITEURS<br />
Progression <strong>tumorale</strong><br />
Facteurs extrinsèques<br />
hormones<br />
inflammation<br />
cytokines<br />
STIMULI<br />
Trombospondine<br />
Endostatine<br />
Angiostatine, vasostatine<br />
Interférons <br />
TIMP<br />
IL10, IL12<br />
Platelet factor 4<br />
VEGF +++<br />
FGF<br />
PDGF<br />
EGF<br />
HGF<br />
Dormance -> prolifération<br />
TGF-<br />
IGF<br />
Angiopoïetin-1<br />
Angiogénine<br />
IL8<br />
G-CSF, GM-CSF
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