IPC. Your expert partner for granules and pellets. - Glatt
IPC. Your expert partner for granules and pellets. - Glatt
IPC. Your expert partner for granules and pellets. - Glatt
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<strong>IPC</strong>.<br />
<strong>Your</strong> <strong>expert</strong> <strong>partner</strong><br />
<strong>for</strong> <strong>granules</strong> <strong>and</strong><br />
<strong>pellets</strong>.<br />
<strong>IPC</strong> (International Process<br />
Center GmbH) is a member<br />
of the world-wide <strong>Glatt</strong><br />
Group <strong>and</strong> specialises in<br />
contract manufacturing<br />
of <strong>pellets</strong> <strong>and</strong> <strong>granules</strong> of<br />
all types. Our modern<br />
production equipment <strong>and</strong><br />
our <strong>expert</strong>ise are avail-<br />
able to customers in the<br />
food/feed, pharmaceutical<br />
<strong>and</strong> chemical industries.<br />
Qualified, highly motivated<br />
staff provide a wide range<br />
of top-quality services at<br />
our sites in Dresden <strong>and</strong><br />
Weimar.<br />
Technology that's<br />
ahead of the rest.<br />
<strong>IPC</strong> is able to make use of<br />
the decades of experience<br />
<strong>and</strong> <strong>expert</strong>ise offered by<br />
the <strong>Glatt</strong> Group, one of the<br />
world's leading plant<br />
manufacturers in the field<br />
of fluidised bed technology.<br />
Through the practical<br />
application of the latest<br />
developments, <strong>IPC</strong> is able<br />
to offer the most up-to-<br />
date process technology at<br />
all times.<br />
<strong>IPC</strong>.<br />
There are lots of good<br />
reasons to use our services:<br />
Access to the techno<br />
logies of the future.<br />
As a customer of <strong>IPC</strong>, you<br />
can test all sorts of differ-<br />
ent process technologies in<br />
the development of new<br />
products <strong>and</strong> transfer the<br />
results directly to achieve<br />
the best manufacturing<br />
process. Highly qualified<br />
staff <strong>and</strong> ultra-modern<br />
laboratories provide you<br />
with support in process<br />
development.<br />
Faster market<br />
launches.<br />
<strong>IPC</strong>'s experience allows you<br />
to modify your products <strong>and</strong><br />
processes faster. Because of<br />
the close connection with<br />
plant construction, specific<br />
process technology require-<br />
ments can be realised<br />
immediately, guaranteeing<br />
our customers that their<br />
market launches will be well<br />
ahead of the competition!<br />
Transfer of process<br />
<strong>expert</strong>ise.<br />
A precise knowledge of<br />
process technology reduc-<br />
es costs <strong>and</strong> risks in the<br />
later development of an<br />
independent production.<br />
Operator training at <strong>IPC</strong><br />
ensures a smooth transfer<br />
of knowledge.<br />
Production around<br />
the clock.<br />
Our uninterrupted 3-shift<br />
operation offers you<br />
maximum flexibility in<br />
production.<br />
Avoiding bottlenecks.<br />
Use the services offered<br />
by <strong>IPC</strong> to cover peaks<br />
in dem<strong>and</strong> so that you only<br />
need to design your own<br />
production capacities <strong>for</strong><br />
normal requirement levels.<br />
1
Drying.<br />
Our fluidised bed systems<br />
are ideal <strong>for</strong> the rapid dry-<br />
ing of temperature-sensitive<br />
products. These materials<br />
are fluidised in the pretreat-<br />
ed, warm flow of air. The<br />
ideal heat exchange <strong>and</strong> the<br />
associated vaporization<br />
conditions in the fluidised<br />
2<br />
Do you already know<br />
what you want?<br />
Are you looking <strong>for</strong> the<br />
best solution?<br />
<strong>IPC</strong> can offer you<br />
tailormade processes <strong>for</strong><br />
tailormade products:<br />
bed produce much shorter<br />
drying times than other<br />
processes, guaranteeing<br />
optimum protection of the<br />
product with a uni<strong>for</strong>m<br />
temperature distribution.<br />
Temperature <strong>and</strong> humidity<br />
are measured online.<br />
Wet granulation.<br />
Many areas require dust-<br />
free yet mechanically stable<br />
products. Granulates from<br />
our wet mixers are character-<br />
ised by their free flowing<br />
structures, since the prod-<br />
uct is mechanically com-<br />
pacted during the process.<br />
After equalization in the wet<br />
sieve, the product is then<br />
sucked directly into the flu-<br />
idised bed <strong>for</strong> drying.<br />
Principles of drying Dried <strong>granules</strong><br />
Wet granulation in the vertical granulator<br />
Vertical Granulator VG 100
Fluidised bed<br />
granulation.<br />
Fine powders can cause<br />
major problems in process-<br />
ing, not only because of the<br />
dust emitted, but also by<br />
their poor flowability <strong>and</strong><br />
low solubility. Top spray<br />
agglomeration with solvents<br />
or binder liquids creates a<br />
porous granule structure<br />
Porous fluidised bed<br />
granule<br />
which dramatically improves<br />
flow behaviour, suitability<br />
<strong>for</strong> further processing <strong>and</strong><br />
the dispersion qualities of<br />
the products.<br />
Principles of granulating <strong>and</strong> top spray coating<br />
Fluidised bed granulation <strong>and</strong> top spray coating in the GPCG 500/800<br />
Top Spray Coating.<br />
The coating of sensitive<br />
products can considerably<br />
improve shelf life <strong>and</strong> open<br />
up new areas of applica-<br />
tion. It can also prevent<br />
individual substances react-<br />
ing with each other <strong>and</strong><br />
stop oxidation reactions. In<br />
addition, the dispersion<br />
characteristics of the prod-<br />
ucts can also be modified.<br />
Coated granule<br />
Suitable film materials are<br />
finely atomised via noz-<br />
zles to <strong>for</strong>m a film on the<br />
surface of the product that<br />
completely encloses it. The<br />
process is particularly<br />
suitable <strong>for</strong> coating with<br />
waxes <strong>and</strong> hot melts.<br />
3
Bottom Spray Coating.<br />
For high-quality films <strong>for</strong><br />
the controlled release<br />
of ingredients, the film<br />
solution is sprayed onto<br />
the product via a nozzle in<br />
the bottom of the contain-<br />
er. The product continually<br />
passes through a Wurster<br />
column positioned around<br />
the nozzle, guarantee-<br />
ing even encapsulation of<br />
every particle. The fine<br />
atomisation of the coating<br />
solution <strong>and</strong> the particular<br />
layout of the nozzle means<br />
that even the finest parti-<br />
cles of around 50 µm can be<br />
enclosed, in contrast to Top<br />
Spray Coating.<br />
4<br />
Principles of bottom spray coating<br />
Bottom spray coater product<br />
container<br />
Bottom spray coating in the GVW 32"<br />
Pellet with various coatings
Pelletisation.<br />
Compact particles are<br />
created by wet granulation,<br />
extrusion <strong>and</strong> subsequent<br />
spheronisation. Subsequent<br />
drying <strong>and</strong> possible coat-<br />
ing of the <strong>pellets</strong> is carried<br />
out efficiently in the<br />
fluidised bed.<br />
Vertical Granulator<br />
Principles of pellet manufacture<br />
Material container <strong>for</strong><br />
fluidised bed drying<br />
Wet granulation in the vertical granulator VG 800<br />
Extruder<br />
Spheroniser<br />
Emptying of the spheroniser<br />
5
Sieving <strong>and</strong> milling<br />
technology.<br />
Various sieving technologies<br />
are available <strong>for</strong> screening<br />
of the end product as well<br />
as sizing of the granule<br />
structure.<br />
Classifier sieve<br />
6<br />
Mixing.<br />
All kinds of additives<br />
can be blended in the<br />
container mixer with<br />
different batch sizes, up<br />
to 1300 l/batch.<br />
Charging the mill<br />
Dust-free charging of a container<br />
Milling.<br />
The raw materials can be<br />
milled to various grain sizes<br />
using impact pulverizers.
<strong>IPC</strong>.<br />
Staying ahead<br />
through service.<br />
Process development.<br />
<strong>IPC</strong> offers you tailor-made<br />
processes <strong>for</strong> tailor-made<br />
products – <strong>and</strong> not only on<br />
a production scale. You can<br />
also test the processes<br />
using laboratory/pilot equip-<br />
ment of different sizes. A<br />
GMP facility at <strong>Glatt</strong>, in<br />
Binzen, is available <strong>for</strong><br />
pharmaceutical <strong>and</strong> food<br />
products whereas manufacturing<br />
processes <strong>for</strong><br />
chemical products are<br />
developed in a separate<br />
laboratory. The processes<br />
can then be transferred<br />
easily to production after<br />
scale-up.<br />
Laboratory tests<br />
Process optimisation.<br />
Trials in our own technical<br />
facilities allow processes to<br />
be optimised <strong>and</strong> guarantee<br />
the best possible start to<br />
production.<br />
Inprocess control.<br />
Our own laboratories carry<br />
out quality monitoring including<br />
continuous in-process<br />
control in accordance with<br />
the agreements reached.<br />
Preliminary tests in our<br />
laboratories <strong>and</strong> analyses<br />
round off the perfect quality<br />
assurance system.<br />
Retained sample<br />
Process<br />
documentation.<br />
A detailed process documentation<br />
of all batches<br />
including storage of retained<br />
samples guarantees traceability<br />
<strong>and</strong> means that the<br />
agreed quality parameters<br />
can be monitored.<br />
Charging the Bag-in-Box<br />
Making up.<br />
The end product can be<br />
made up in various containers:<br />
Big-Bags, sacks,<br />
barrels, cartons, cans or<br />
bottles. Naturally, <strong>IPC</strong> can<br />
also carry out labeling if<br />
required.<br />
Finished goods store<br />
Storage.<br />
The buffer store <strong>for</strong> raw<br />
<strong>and</strong> finished products means<br />
we can react flexibly to<br />
your logistics. A separate<br />
coldroom is available <strong>for</strong><br />
sensitive products.<br />
Logistics.<br />
If required, <strong>IPC</strong> can also<br />
take over complete purchase<br />
of raw materials, dispatch<br />
<strong>and</strong> environmentally<br />
correct disposal of waste.<br />
7
8<br />
<strong>IPC</strong> plants<br />
Plant type Batch size Suitable <strong>for</strong> Processing of solvents<br />
Fluidised bed granulator/ up to 400 kg Food/Pharma Yes<br />
Top spray coater<br />
up to 700 kg Food/Feed No<br />
up to 1200 kg Food/Feed No<br />
up to 700 kg Fine Chemicals Yes<br />
Bottom spray coater up to 300 kg Food/Pharma Yes<br />
up to 600 kg Food/Feed/Fine Chemicals No<br />
Wet granulator 600 l Food/Feed No<br />
600 l Fine Chemicals Yes<br />
Extruder dep. on product Food/Feed No<br />
Spheroniser up to 400 kg/h Food/Feed No<br />
Classifier sieves dep. on product Food/Feed/Pharma/Fine Chemicals No<br />
Sizing sieves - dep. on product Food/Feed/Pharma/Fine Chemicals No<br />
<strong>for</strong> dried <strong>and</strong> moist products<br />
Universal mill dep. on product Food/Feed No<br />
dep. on product Fine Chemicals No<br />
Container mixer 1300l/Charge Food/Feed/Pharma/Fine Chemicals No<br />
Filling in bottles, cans, sacks, Food/Feed/Pharma/Fine Chemicals –<br />
Big-bags, barrels